Performance Tip for HTTP Downloads « Zoompf – Next Generation Web Performance HTTPWatch has an interesting article today on their blog entitled “Four Tips for Setting up HTTP File Downloads.” They offer some great advice to make sure your downloadable files work across all browsers and are saved using the appropriate name. However they didn’t include a very important feature that all websites offering large file downloads should have: support for resumable downloads! As we will see this is an essential performance feature that improves user experience while reducing bandwidth costs. Partial Downloads and the Range Header HTTP/1.1 added many exciting features over HTTP/1.0. This seemingly odd and esoteric feature is actually quite powerful because it allows for browsers to resume HTTP downloads! Here we see the browser is trying to download a large PDF file named “report.pdf” which is approximately 9 megabytes. A few key points about resumable downloads and range requests: Conclusions Want to see what performance problems your website has?
Solitude and Leadership: an article by William Deresiewicz | The American Scholar Essays - Spring 2010 Print If you want others to follow, learn to be alone with your thoughts By William Deresiewicz The lecture below was delivered to the plebe class at the United States Military Academy at West Point in October 2009. My title must seem like a contradiction. Leadership is what you are here to learn—the qualities of character and mind that will make you fit to command a platoon, and beyond that, perhaps, a company, a battalion, or, if you leave the military, a corporation, a foundation, a department of government. We need to begin by talking about what leadership really means. So I began to wonder, as I taught at Yale, what leadership really consists of. See, things have changed since I went to college in the ’80s. So what I saw around me were great kids who had been trained to be world-class hoop jumpers. That is exactly what places like Yale mean when they talk about training leaders. But I think there’s something desperately wrong, and even dangerous, about that idea.
Website Performance | Générateur de Sprites CSS Roche to provide EU regulatory update on Avastin in metastatic breast cancer Basel, 24 September 2010 Roche to provide EU regulatory update on Avastin in metastatic breast cancer Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today that on behalf of the European Medicines Agency (EMA), the Committee for Medicinal Products for Human Use (CHMP) has started a review of Avastin® in combination with paclitaxel or docetaxel for the first-line treatment of metastatic breast cancer in view of data from the RIBBON-1 study. Roches believes that based on a positive benefit/risk profile, the RIBBON-1 data support a label expansion of Avastin with Xeloda for the treatment of metastatic breast cancer in addition to the currently approved indication with paclitaxel or docetaxel. The current use of Avastin in its licensed indications including for the treatment of patients with metastatic breast cancer is not affected by this review. About Avastin: Over 5 Years of Transforming Cancer Care About Avastin: Mode of Action About an EU review procedure (referral) About Roche
Pharma Blogging Panel at ACS Boston August 24th, 2010 • 11:08 Welcome to the live coverage of the Chemical & Pharma Blogging panel. Yes, this pharma blog is live blogging the pharma blogging session. It’s very meta. 12:08 A slight delay as the crowds descend upon the boxed lunches. 12:16 Derek Lowe is up first. 12:20: Derek started blogging in January or February of 2002. 12:22 Derek gets about 15-20k pageviews per day. 12:24 Nabakov extensively quoted. 12:25: A way to tell people where drugs really come from. 12:26 Ed Silverman from Pharmalot is up next. 12:28 Ed comes at blogging from a different perspective: “I’m a journalist of all thing.” 12:30 Blogging has been an interesting experience–writing a blog has been one of the best career decisions he made. 12:31 Ed also sees the crowd go quiet when he writes about patent stuff. 12:33 Now up, David Kroll of Terra Sigillata 12:35 A pharmacologist by training, but he does play well with chemists. 12:42 Derek Lowe was an inspiration for David’s blog. 12:52 David’s top posts?
Using rivalry to spur innovation - McKinsey Quarterly - Strategy - Innovation Many companies overlook the ability of productive rivalry to stimulate innovation. That could be a loss: Not only has it been a powerful contributor to innovation in the past, but according to Mark Little, the director of General Electric’s Global Research Group, rivalry also has made a difference in his company’s efforts to develop better aircraft engines, composite materials, and power generation equipment. Taken together, the two articles that follow suggest that innovation-minded executives whose R&D groups don’t employ rivalry should be looking for more opportunities to form teams, appreciate differences in their respective approaches, and conduct market tests. Embedding rivalry in a culture where what’s celebrated most is the outcome—a better product or service—can be a powerful positive force. The art of innovation Business leaders tend to raise their eyebrows when they read about parallels between history and modern management—and for good reason. Promoting “collision”
Stuff that occurs to me LeadershipChat Transcript Nov 30, 2010 « fredmcclimans.com Along the way, we hit some key topics, such as the definition of “passion” and how is it nurtured or developed, how vision and passion relate, the dual/symbiotic roles of passion and enthusiasm in leadership, the ways that passion in leaders can drive passion in others (as well as attract people who share the same passion) and how good leaders often know when to step aside and let others utilize their own passion, building both team spirit/focus and a common sense of purpose and ownership. I hope you enjoy the transcript as much as I enjoyed participating in the chat, and I encourage you to follow both this chat and the people below – they are some of the brightest people I know. Feel free to continue this conversation in the comments section below, and if you like this transcript and feel others might as well or would benefit from our discussion, please RT liberally – it’s all about the conversation. And please, remember to read from the bottom up! @wadnikhil @anthonyonesto No worries.
The latest twists in angiogenesis research Medulloblastoma cells (green) are growing around this cerebellar blood vessel and inducing growth of new vessels nearby (red). Courtesy Matija Snuderl & Rakesh Jain. An update last week on angiogenesis research revealed surprising twists in the story of fighting cancer by cutting off the tumor’s blood supply. The latest findings, reported by top researchers at an international pediatric oncology meeting in Boston, show that the story is much more nuanced. Anti-angiogenic drugs can kill some tumors by cutting off their blood supply. A smaller tumor with less blood supply and more hypoxia can be more metastatic than a better-oxygenated larger tumor, confirmed Raghu Kalluri, PhD, in a later talk. However, Jain noted that the doses used in the published animal studies are much higher than those that would ever be prescribed to patients. Rehabilitating vessels Jain’s group is working on how to exploit and expand another paradoxical feature of anti-angiogenic drugs. An option for children
Participatory Epidemiology: Use of Mobile Phones for Community-Based Health Reporting Figures Citation: Freifeld CC, Chunara R, Mekaru SR, Chan EH, Kass-Hout T, et al. (2010) Participatory Epidemiology: Use of Mobile Phones for Community-Based Health Reporting. PLoS Med 7(12): e1000376. doi:10.1371/journal.pmed.1000376 Published: December 7, 2010 This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. Funding: The work is funded thanks to a grant from Google.org. Competing interests: The authors have declared that no competing interests exist. Abbreviations: CDC, US Centers for Disease Control and Prevention; ILI, influenza-like illness; SMS, short message service Summary Points Traditional health systems serve a key role in protecting populations, but are typically hierarchical, and information often travels slowly. Table 1. Table 2.
Unlocking the door - FEATURE Open access is the subject of much discussion among academics and publishers and plays an important role in the communication of peer-reviewed information to scientists, clinicians and educated patients. However, there is substantial disagreement about the open access concept, along with much discussion about the economics of funding an open access communications system for clinical publications. Reactions range from moving with enthusiasm to a new open access publishing model, to experiments in providing as much free or open access as possible, to active lobbying against open access proposals. The idea of open access was born out of research scientists' need to retrieve information quickly and cost-effectively that would enable them to accelerate their own research and, in turn, communicate with their peers quickly and more effectively. It follows the trend towards increasing use of online resources to access published research, in some cases negating the need for paper journals.
Royal Society of Medicine presents “Using the internet to practice medicine” « 3G Doctor Blog On Tuesday 21 September 2010, the Telemedicine and eHealth Section of the Royal Society of Medicine will be hosting an event that will be looking at how to use the internet to practice medicine to increase the efficiency, widen access and improve the quality of care. This is a rare opportunity to learn from Professor Bachman, Professor of Primary Care Medicine at the Mayo Clinic, a renowned world expert in the use of the internet in consultations with patients. Check out his video lecture on the Mayo Clinic Experience by clicking here. The event will be comprised of talks and a workshop covering practical ways to enhance the efficiency of care with important lessons on the reality of achieving this within your busy medical practice, and will appeal to Healthcare Professionals interested in maximizing the use of healthcare resources and learning how to leverage patient access to the internet to improve the quality of care. Like this: Like Loading...
Introduction to Social Influence, Persuasion, Compliance & Propaganda This portion of the Working Psychology website offers a brief introduction to a big topic: social influence, the modern, scientific study of persuasion, compliance, propaganda, "brainwashing," and the ethics that surround these issues. Although these topics aren't always simple (it is, after all, science), I've done my best to make this introduction interesting. Since Aristotle recorded his principles of persuasion in Rhetoric, humans have attempted to define and refine the principles of successful influence. Persuasion has been studied as an art for most of human history. The comparatively young science of social influence, however, can trace its roots to the second world war, when a social psychologist named Carl Hovland was contracted by the U.S. Social scientists attempt to support any assertion with facts. Want a few examples of how social influence works in the real world before you continue? Copyright © 2002 by Kelton Rhoads, Ph.D.