Researchers identify protein that spreads cancer. Tuesday July 14 2015 Researchers found the DNA-PKcs molecules helped spread cancer "Scientists have found a way of preventing the spread of cancer from the site of the original tumour," The Independent reports.
Targeting proteins called DNA-PKcs could prevent cancer cells moving to other parts of the body. This is known as metastatic cancer and is often fatal. The research involved mice as well as tissue samples from more than 200 prostate cancer patients. Patients whose prostate cancer tissue samples showed higher DNA-PKcs levels were more likely to have had cancer progression (metastasis). This research furthers our knowledge about the biology of cancer progression and has identified another possible way to tackle the spread of cancer. Where did the story come from? It was funded by the Prostate Cancer Foundation (PCF), PCF/Movember and Evans Foundation, PA CURE, the US Department of Defense, UCLA, the National Cancer Institute, and the National Institutes of Health. Scientists Confirm That People do Actually Age at Different Rates.
When you turn up at your high school reunion and look around, you might notice something.
Despite all of you being born within one year of each other, some will almost certainly look younger and some older. Indeed, a recent study published in the Proceedings of the National Academy of Sciences has confirmed what many have already observed: People do actually age at a different rate – and some of us much more dramatically than others. While most people in the study had a biological age close to the 38 birthdays they’d racked up, some were significantly younger or older, reflected in the state of their organs, metabolism and mental abilities. Direct link between wound healing, skin cancer seen by researchers. BRISTOL, England, July 1 (UPI) -- Researchers have found that inflammatory cells sent by the immune system to the site of a wound for healing are redirected to pre-cancerous cells they help grow.
While tissue damage and cancer have been linked before, researchers have now seen inflammatory cells called neutrophils be diverted from wounds to pre-cancerous cells in adult zebrafish. "There is a longstanding association between wound healing and cancer, with cancer often described as a 'wound that does not heal,'" said Dr. Nicole Antonio, of the School of Biochemistry at Bristol University, in a press release. Scientists Reverse Aging In Human Cell Line. It’s the Holy Grail for medicine: how to stop or even reverse aging.
With teams of scientists the world over frantically trying to figure out what may cause it, studying everything from nematode worms to naked mole-rats, it seems that a team from Japan might have taken a step forward. Defects in mitochondria, called “the powerhouse of the cell,” as they produce the cells' energy, have long been associated with causing aging-related characteristics such as hair and weight loss, curvature of the spine and osteoporosis. One of the most popular current theories on why we age is called “the mitochondrial theory of aging.” It’s been thought that accumulated mutations in the DNA found in mitochondria are the reason behind this.
Missing link found between brain, immune system. Vessels directly connecting brain, lymphatic system exist despite decades of doctrine that they don’tFinding may have substantial implications for major neurological diseases Game-changing discovery opens new areas of research, transforms existing onesMajor gap in understanding of the human body revealed‘They'll have to change the textbooks’ In a stunning discovery that overturns decades of textbook teaching, researchers at the School of Medicine have determined that the brain is directly connected to the immune system by vessels previously thought not to exist.
That such vessels could have escaped detection when the lymphatic system has been so thoroughly mapped throughout the body is surprising on its own, but the true significance of the discovery lies in the effects it could have on the study and treatment of neurological diseases ranging from autism to Alzheimer’s disease to multiple sclerosis. "Instead of asking, 'How do we study the immune response of the brain?' New Method Could Reveal Your Entire Viral Infection History With A Single Drop Of Blood. By analyzing just a single drop of blood, scientists could reveal every virus you’ve ever been infected with.
This new method, developed by researchers from Howard Hughes Medical Institute (HHMI), is called ‘Virscan’ and it could revolutionize existing diagnostics. Traditional blood tests, known as ELISA assays, are only able detect one pathogen at a time and scientists have yet to develop ELISA assays against all viruses. Is Your Nervous System Being Hacked by Bacteria in Your Gut? The More Hours You Work, the More You Drink, Study Says. David Wolpe is the Max Webb Senior Rabbi of Sinai Temple in Los Angeles.
Religion is America is fading. According to a new Pew Research Center report, almost 23% of all U.S. adults in 2014 said they were religiously unaffiliated, up from about 16% in 2007. While most of the unaffiliated describe themselves as “nothing in particular,” a growing share say they are atheist or agnostic. Why is religion in trouble, and should we be fighting to save it? Some religious groups are holding fairly steady, including the evangelical and historically black Protestant traditions. The first adversary religion faces is self-sufficiency. The second adversary religion faces is a scientific hegemony over the life of the mind. Study Of More Than 3,500 Human Brains Reveals The Cause Of Alzheimer's Disease.
After examining more than 3,500 donated brains, scientists have gathered evidence to suggest that a rogue protein, tau, which has long been suspected to play a role in the development of Alzheimer’s, is the major driver of cognitive decline in this disease.
These new findings downplay the role of amyloid, another dysfunctional protein that builds up as the condition progresses and has been the focus of much Alzheimer’s research. Although this discovery does not mean that the debate over which protein is the biggest contributor to disease progression is over, it does have implications for future research, and the scientists suggest that therapeutics should now focus on tackling tau, rather than amyloid. The study has been published in Brain.
Untitled. Should We All Be In 'Monogamish' Relationships? There’s an argument brewing that says monogamy is not best for a successful relationship.
But is there any science behind it? (Photo: Getty Images) Chris Messina invented the hashtag. He also believes it is time to re-invent contemporary sexuality, which is why he practices something he refers to as “non-monogamy.” Autism and Air Pollution: New Study Bolsters Suspected Link. Pregnant women may nearly double their risk of giving birth to a child with autism by inhaling smog spewed by vehicles or smoke stacks, according to a new Harvard study that could help unlock the deepest autism mysteries.
The research, released Thursday, fortifies previous scientific findings that linked air pollution to autism. And it offers fresh insights by showing women in their third trimesters seem most vulnerable if they breathe in elevated levels of tiny airborne particles emitted by power plants, fires and automobiles. "We found an association that was specific to pregnancy and especially to the third trimester, identifying a window, which might shed a light on processes that are happening that can lead to autism," said Marc Weisskopf, the report's senior author and associate professor of environmental and occupational epidemiology at the Harvard School of Public Health. The higher the exposure rate, the greater the risk, he found. The association between discontinuing hormonal contraceptives and wives’ marital satisfaction depends on husbands’ facial attractiveness. Author Affiliations Edited by Steven J.
C. Gaulin, University of California, Santa Barbara, CA, and accepted by the Editorial Board October 16, 2014 (received for review August 1, 2014) Researchers make blood vessels grow by shining a light on skin. Any fan of Star Trek knows that simply shining light on an injury will heal many wounds in the future. Now scientists have brought that future a bit closer. In a new study, researchers have found a way to stimulate the growth of blood vessels—an important part of healing—by hitting the skin with ultraviolet light.
In the past decade, scientists have used light to manipulate the chemistry of cells in a dish—but they’ve struggled to do the same in living organisms. “There are hundreds of different types of cells; you have a lot more other biological molecules present,” says bioengineer Andrés García of the Georgia Institute of Technology in Atlanta. So García and colleagues turned to a water-based gel, or hydrogel, impregnated with a molecule called RGD peptide. The scientists then moved to animal experiments. Marijuana And Cancer: Scientists Find Cannabis Compound Stops Metastasis In Aggressive Cancers. A pair of scientists at California Pacific Medical Center in San Francisco has found that a compound derived from marijuana could stop metastasis in many kinds of aggressive cancer, potentially altering the fatality of the disease forever.
"It took us about 20 years of research to figure this out, but we are very excited," said Pierre Desprez, one of the scientists behind the discovery, to The Huffington Post. "We want to get started with trials as soon as possible. " The Daily Beast first reported on the finding, which has already undergone both laboratory and animal testing, and is awaiting permission for clinical trials in humans. Desprez, a molecular biologist, spent decades studying ID-1, the gene that causes cancer to spread. Meanwhile, fellow researcher Sean McAllister was studying the effects of Cannabidiol, or CBD, a non-toxic, non-psychoactive chemical compound found in the cannabis plant.
Paul Ryan’s budget flimflam. By Editorial Board October 1, 2012 PAUL RYAN wants to tell you about the wonders of the 20 percent cut in tax rates that he and running mate Mitt Romney propose. Money in the House elections, in 8 charts. This post was prepared in collaboration with Alexander Furnas and Alex Engler. With just over a month before the election, the general consensus is that Democrats will have a tough time picking up the 25 seats they need to win back the house, despite some protestations. But when it comes to the money, Republicans appear to be in solid shape. Jon Stewart Rails Against Fox News' Hypocritical Coverage Of School Lunch Changes.
63,000-Year-Old Modern Human Skull Found in Laos. Greek police send crime victims to neo-Nazi 'protectors' Greece's far-right Golden Dawn party is increasingly assuming the role of law enforcement officers on the streets of the bankrupt country, with mounting evidence that Athenians are being openly directed by police to seek help from the neo-Nazi group, analysts, activists and lawyers say. Is Sitting Killing Me? Autism-Pesticide Link Found in Calif. Study.
A California study out Monday found that pregnant women who live near farms where pesticides are applied had a two-thirds higher risk of having children with autism. The findings in the journal Environmental Health Perspectives examine the association between living near commercial pesticide applications and having offspring with autism, but do not show cause-and-effect. Spinal cord research offers unexpected hope to people with paralysis. Being gay may be in the DNA, researchers say. Are Happy Gut Bacteria Key to Weight Loss? A cluster of Enterobacter cloacae bacteria Eye of Science / Science Source. Middle-Aged Men, Too, Can Blame Estrogen for That Waistline. Bacterial toxins cause deadly heart disease: Superantigens produced by staph bacteria are required for deadly effects of infective endocarditis and sepsis. PTSD may be prevented, researchers find. New source for regenerative stem cells? Your fat, study suggests.
Eggs, Too, May Provoke Bacteria to Raise Heart Risk. Scientists Find Achilles’ Heel of Cancer Cells. Scientists create road map to metabolic reprogramming for aging (Nov. 29. Age-related dementia may begin with neurons' inability to rid themselves of unwanted proteins. Being Overweight Is Linked to Lower Risk of Mortality. Fructose Linked To Overeating, Obesity In New Brain Imaging Study. How Dark Chocolate May Guard Against Brain Injury From Stroke - 05/05/2010. Scientists create 'endless supply' of myelin-forming cells.
Canadian scientists discover cause of high cholesterol. Researchers Reveal the Key element related to the activation of Brown Adipocytes. Breakthrough made in developing antibodies against HIV. Cannabis eases multiple sclerosis (MS) stiffness per study published in neurology journal. Scientists make old muscles young again in attempt to combat aging. Part Man, All Woman: Scientists Find Male DNA in Women's Brains. Skin cancer detection breakthrough. Scientists Find Enzyme That Kills Alzheimer's Protein. Scientists discover how an out-of-tune protein leads to heart muscle failure. Chronic Pain May Depend on Emotional Reaction to Injury. MIT discovers the location of memories: Individual neurons. Scientists Turn Skin Cells Into Cardiac Cells to Help Failing Hearts.
Breastfeeding linked to healthy infant gut: Bacterial colonization leads to changes in the infant’s expression of genes. Researchers Find an Epigenetic Culprit of Memory Decline - HDAC2 enzyme. Researchers find new evidence on how cholesterol gets moved from HDLs to LDLs. Alzheimer's brain plaques 'rapidly cleared' in mice. How Your Cat Is Making You Crazy - Magazine. Scientists in Scotland use skin samples to create human brain cells. Scientists reveal how females store sperm for decades. ‘Foldit’ Gamers Solve AIDS Puzzle that Baffled Scientists for Decade. Common Cause of ALS Discovered. New drug could cure nearly any viral infection. Scientists find cure for rotting food. Using super microscope scientists find body’s immunity “switch” Healthy sex life makes men live longer. Smoking Damages DNA Within Minutes, Research Shows.
Autism researchers find scores of gene mutations.