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Synthetic Biology and metabolic engineering

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This Swimming Stingray Robot Is Powered by Real, Living Rat Cells. Microsoft's "Biological Computing" Lab Aims To Fight Diseases By Reprogramming Cells. Microsoft's researchers don't talk about "curing" cancer.

Microsoft's "Biological Computing" Lab Aims To Fight Diseases By Reprogramming Cells

Instead, they are aiming to "solve" it. The technology behemoth is best known for its operating systems and business software, and since 2014, under CEO Satya Nadella, it's focused much of its energy on plotting a future for mainstay products such as Windows and Office. But the company has also quietly built up a presence in medical research. In Cambridge, U.K., it has 150 scientists and software developers working on a wide variety of projects at its little-known "biological computation" unit, which includes a newly installed wet lab.

CRISPR/Cas9 and DNA editing

This Genetically-Engineered Bacteria Can Inhale CO2 and Produce Energy. Newest Discovery Moves Us One Step Closer To Making Synthetic Organisms With Reverse Biochemistry. Southpaw DNA and Righty Amino Acids.

Newest Discovery Moves Us One Step Closer To Making Synthetic Organisms With Reverse Biochemistry

This Device Lets You Brew Your Own Drugs At Home. Prototype A machine prototype called Farma can let you manufacture your daily prescription of drugs right in your own home.

This Device Lets You Brew Your Own Drugs At Home

Designed by MIT Media Lab graduate Will Patrick, the concept tech features a green cylinder and uses blue-green algae that’s genetically engineered to produce pharmaceutical drugs. After the drugs are produced, the device then measures, filters, and dries it into a powder. Once in powder form, it can then be molded into pill form. Image credit: Farma.


'Squid teeth' plastic self-heals with water. Scientists derived the genetic code of squid ring teeth to develop a polymer that self-heals with a single drop of water.

'Squid teeth' plastic self-heals with water

The material potentially could extend the life of medical implants, fiber-optic cables, and other hard-to-repair objects, researchers say. “There are other materials that are self-healing, but not with water.” “What’s unique about this plastic is the ability to stick itself back together with a drop of water,” says Melik Demirel, professor of engineering science and mechanics at Penn State. “There are other materials that are self-healing, but not with water.” Demirel and colleagues looked at the ring teeth of squid collected around the world—in the Mediterranean, Atlantic, near Hawaii, Argentina, and the Sea of Japan—and found that proteins with self-healing properties are ubiquitous.

Another Milestone in Hybrid Artificial Photosynthesis. Laser technique for low-cost self-assembly of nanostructures. The Pentagon Is Putting Big Money Into Synthetic Biology - BuzzFeed News. New DNA construct can set off a “mutagenic chain reaction” Nanocrafter: Playing a Game of Synthetic Biology - Citizen Science Salon : Citizen Science Salon. Image Credit: Nanocrafter On its surface, it looks like just another science puzzle game.

Nanocrafter: Playing a Game of Synthetic Biology - Citizen Science Salon : Citizen Science Salon

In reality, the game is part of a broader goal to enable non-scientists to contribute to synthetic biology research. ‘It’ is Nanocrafter, a project created by researchers and game developers at the Center for Game Science at the University of Washington. They are the same team behind the citizen science project FoldIt. “Most citizen science games are designed to gather data for a specific research question. Nicholas Negroponte on Biotechnology and Future Learning. By Big Think Editors When Nicholas Negroponte spoke at the inaugural TED event in 1984, he made five predictions (though he calls them extrapolations) that more or less came true.

Nicholas Negroponte on Biotechnology and Future Learning

Negroponte was working off 15 years of research and forecasted what he could reasonably expect to happen in the field of digital technology. Artificial Enzymes from Artificial DNA Challenge Life As We Know It. Artificial Enzymes from Artificial DNA Challenge Life As We Know It In the decade or so since the Human Genome Project was completed, synthetic biology has grown rapidly.

Artificial Enzymes from Artificial DNA Challenge Life As We Know It

Y Combinator, Move Over For IndieBio: A Second Biotech Accelerator. Bernadette Tansey10/9/14 Y Combinator, which set off a whirlwind of skeptical commentary when it opened its highly ranked tech accelerator program to biotechnology startups last spring, now has some company.

Y Combinator, Move Over For IndieBio: A Second Biotech Accelerator

SOS Ventures, the international VC firm that already holds accelerator programs for software and hardware company founders, is launching a separate accelerator called IndieBio in San Francisco and the city of Cork, Ireland, for entrepreneurial teams in fields that include synthetic biology. Hagfish Slime: Biomaterial Of The Future? I don’t like to admit that there are many things that are as badass in the marine world as sharks, but hagfish definitely give them a run for their money.

Hagfish Slime: Biomaterial Of The Future?

Hagfish are primitive, eel-like creatures that spend most of their lives slithering along the ocean floor, scavenging dead and dying fish. They’re spineless, virtually blind, have no jaws and have barely changed over the last 300 million years. They’re not sounding very tough right now, so what makes them so special? Well, hagfish have a sticky trick up their sleeves. When attacked or threatened, they exude a gelatinous slime into the water that can quickly smother the gills and mouth of a predator, thwarting the attack. Seven fabrics inspired by nature: from the lotus leaf to butterflies and sharks. With technology poised to change the way we dress in the future, here are seven examples of innovative fabrics that take their cue from the natural world.

Seven fabrics inspired by nature: from the lotus leaf to butterflies and sharks

Hooked on Velcro. Movie: Julian Melchiorri on the first synthetic biological leaf. The "first man-made biological leaf" could enable humans to colonise space Dezeen and MINI Frontiers: RCA graduate Julian Melchiorri says the synthetic biological leaf he developed, which absorbs water and carbon dioxide to produce oxygen just like a plant, could enable long-distance space travel.

"Plants don't grow in zero gravity," explains Melchiorri. "NASA is researching different ways to produce oxygen for long-distance space journeys to let us live in space. This material could allow us t0 explore space much further than we can now. " Two New Letters for the DNA Alphabet. Scientists keep getting better at rewriting the book of life. Adding, deleting, and splicing genes has become routine, and some researchers are now even designing DNA for creatures. While many are hard at work rearranging letters on the page, a new experiment is redefining the concept of synthetic biology by writing new letters. As they reported today in the journal Nature, a team of biologists led by Floyd Romesberg at the Scripps Research Institute have expanded the genetic alphabet of DNA—the As, Cs, Gs, and Ts that write the book of life—to include two new letters.

The scientists showed that their letters could be integrated into the DNA of a living creature (an E. coli bacterium) and increase exponentially the amount of information the genetic code can store. Biodegradable Plastic Option From Shrimp Shells. From the depths of the oceans to stomachs of whales waste plastics are out of control. Scientists Engineer First Bone Marrow-On-A-Chip. Scientists from Harvard’s Wyss Institute for Biologically Inspired Engineering have described a method for producing a device which closely mimics the composition and architecture of actual bone marrow. If synthetic biologists think like scientists, they may miss their eureka moment. Bioengineers Build Circuit Board Modeled On The Human Brain.

Bio-inspired transparent synthetic materials could protect cars and people. This Could Be the First Animal to Live Entirely Inside a Computer. DNA nanobots deliver drugs in living cockroaches - health - 08 April 2014. Self-healing engineered muscle grown in ‘bionic mouse’ Engineered muscle fiber stained to observe growth after implantation into a mouse (credit: Duke University) Erasing A Genetic Mutation. CAMBRIDGE, MA -- Using a new gene-editing system based on bacterial proteins, MIT researchers have cured mice of a rare liver disorder caused by a single genetic mutation. The findings, described in the March 30 issue of Nature Biotechnology, offer the first evidence that this gene-editing technique, known as CRISPR, can reverse disease symptoms in living animals.

CRISPR, which offers an easy way to snip out mutated DNA and replace it with the correct sequence, holds potential for treating many genetic disorders, according to the research team. Engineered bacteria produce biofuel alternative for high-energy rocket fuel. Engineers design 'living materials': Hybrid materials combine bacterial cells with nonliving elements that emit light. Inspired by natural materials such as bone -- a matrix of minerals and other substances, including living cells -- MIT engineers have coaxed bacterial cells to produce biofilms that can incorporate nonliving materials, such as gold nanoparticles and quantum dots. These "living materials" combine the advantages of live cells, which respond to their environment, produce complex biological molecules, and span multiple length scales, with the benefits of nonliving materials, which add functions such as conducting electricity or emitting light.

Reprogrammed Bacteria Build Self-Healing 'Living Materials' Monsanto Owns Us: The Monopoly of Seeds and Intellectual Property Rights. 'Iron Man' plants are supercharged by nanotech power - life - 16 March 2014. Trends in Biotechnology - Biotechnological potential of the fungal CTG clade species in the synthetic biology era. How Food Poisoning (E.Coli) Could be the Future Bio-fuel. Scientists discover double meaning in genetic code. Proto-Organelles for Synthetic Cells. SynBio Consulting. Gut Microbes and Autism. New method of DNA editing allows synthetic biologists to unlock secrets of a bacterial genome.

Human stem cells converted to functional lung cells. Advancements in High-Speed DNA Synthesis to Drive Growth in the Global Synthetic Biology Market, According to New Report by Global Industry Analysts, Inc. Engineering Life. Glowing plants and DIY bio succeed on Kickstarter. Glowing Plant. Organs on Demand. Converting fat cells from liposection to liver cells in nine days — a regenerative medicine breakthrough.