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Synthetic Biology

Synthetic Biology
Related:  Synthetic & Systems Biologybiohack A synthetic biology approach to shed light onto the black box of the brain | Poster | BioBricks Foundation SB6.0: The Sixth International Meeting on Synthetic Biology Yagiz Alp Aksoy, Suja Mohammed, Paul Pilowsky Australian School of Advanced Medicine, Macquarie University, Sydney, Australia, Australia Neurons play a crucial role in the regulation of cardiovascular and cardiorespiratory systems yet functional roles of different neuronal phenotypes remain unclear. In order to elucidate mechanisms underlying many neurological and cardiovascular disorders, a better understanding of the functional and the physiological role of specific neurons is crucial. Here we describe an entirely novel synthetic biology approach for selectively investigating the identification, function and regulation of different types of neurons by expressing genes encoding fluorescent proteins, ribosome inactivating proteins and light-activated ion channels under the control of synthetically engineered neuron-specific promoters.

Biologie synthétique Un article de Wikipédia, l'encyclopédie libre. La biologie synthétique est un domaine scientifique combinant biologie et principes d'ingénierie dans le but de concevoir et construire (« synthétiser ») de nouveaux systèmes et fonctions biologiques. Objectifs[modifier | modifier le code] Les objectifs de la biologie synthétique sont de deux types : Tester et améliorer notre compréhension des principes gouvernant la biologie (apprendre en construisant).Construire de façon fiable des organismes accomplissant des fonctions biologiques complexes répondant à diverses applications (énergie, santé par exemple). Concepts[modifier | modifier le code] Modifier le vivant pose aussi des questions philosophiques et éthiques nouvelles et complexes, en relançant la question de la brevetabilité du vivant ou de ses produits et plus généralement de la propriété intellectuelle. Histoire[modifier | modifier le code] Première génération : les années 1900[modifier | modifier le code]

Edge Master Class 2009 THE CURRENT CATALOG OF LIFE By Ed Regis In their futuristic workshops, the masters of the Synthetic Genomics, Craig Venter and George Church, play out their visions of bacteria reprogrammed to turn coal into methane gas and other microbes programmed to create jet fuel 14. Synthetic genomics, the subject of the conference, is the process of replacing all or part of an organism's natural DNA with synthetic DNA designed by humans. The specter of "biohackers" creating new infectious agents made its obligatory appearance, but synthetic genomic researchers are, almost of necessity, optimists. Church and his Harvard lab team have already programmed bacteria to perform each of these functions separately, but they have not yet connected them all together into a complete and organized system. But tumor-killing microbes were only a small portion of the myriad wonders described by Church. Church is also founder and head of the Personal Genome Project, or PGP. [ Permalink ]

Getting Ready for Synthetic Biology Since the completion of the Human Genome Project in 2003, scientists have expanded their knowledge of how living cells work with new approaches including genomics, proteomics, and systems biology. Yet it is another development--the ability not only to understand but also to synthesize genes at a speed and cost unthinkable just a few years ago--that has spurred, arguably, the greatest paradigm shift in recent biology: Today, many scientists are not content merely to analyze and understand life. They want to create it. Synthetic biology, the synthesis of biological components and devices and the redesign or creation of new life forms, has enormous potential. John Glass, a senior microbiologist in the synthetic biology group at the J. Today, synthetic biology is still in its infancy. A Multidisciplinary Approach to Life Brooke Dill, JCVI John Glass At least as important as the field you come from is a willingness to meet other disciplines halfway. A Field in Synthesis Courtesy, Andrés Moya

The 15th International Conference on Systems Biology 2014 DIYbio/FAQ From OpenWetWare DIYbio FAQ v1.5: "The biohacker's FAQ" This FAQ for DIYbio is actively maintained by it's editors, and by you! Edit your contributions directly or email updates to the DIYbio email list, Major contributors (in alphabetical order): The contents of this FAQ are copyright under the OpenWetWare Copyright policy (Creative Commons Attribution-ShareAlike 3.0 Unported). This Frequently Asked Questions document is for the DIYBio mailing list. 1.0 - copied on 4/7/2009 from 1.1 - some updates to clarify original version 1.2 - new sections, reorg, + sections about DIY agar DOI:10.1007/BF00152620 1.3 - expand projects sections. DIYbio is an organization that aims to help make biology a worthwhile pursuit for citizen scientists, amateur biologists, and DIY biological engineers who value openness and safety. What is DIYbio's mission? -- Len Sassaman, DIYbio google group Schmidt M, 2008. IRGC 2008. Other Papers:

Teams — Institute of Systems & Synthetic Biology The MEGA team analyses how the topology of regulatory biological networks unfolds in time (dynamical studies) and space; this latter point being totally original. We also study links between transcription regulation and DNA replication and segregation, as well as the control of DNA replication by central carbon metabolism. On the topological level, three original methods have been developed: 1) detection of gene position regularities along chromosomes (Fig. 1); 2) numerical simulation of the folding of a chromosome bound to bi-valent clustering transcription factors (Fig. 2); 3) bioinformatics use of gene position and of gene promoter consensus sequences in order to predict transcriptional interaction maps. The results obtained change our view of nuclear functional organization, as well as of genome evolution and organization. Logical approaches of the dynamics of regulatory biological networks are also used to prune models based on spatial information. Figure 3

Lettre ouverte aux chercheurs en biologie synthétique | Et vous n'avez encore rien vu... Le 8 Juillet 2013, des militants de Luddites200 et Biofuelwatch ont distribué un tract aux participants à la conférence Synbio 6.0, la principale conférence internationale de chercheurs en biologie synthétique [qui se tiens à Londres]. À notre avis, la biologie synthétique est l’une des technologies en cours d’élaboration les plus dangereuses actuellement, qui exprime sous une forme extrême de nombreuses idées technocratiques que les Luddites combattaient. Lors de la révolution industrielle, les machines étaient considérées comme plus efficace que les travailleurs; avec la biologie synthétique, l’objectif est de remodeler génétiquement vie elle-même conformément aux principes d’ingénierie, afin de la rendre «plus efficace» que les résultats issus du bricolage de l’évolution. Voici le texte que nous leur avons distribué. Lettre ouverte aux participants de Synbio 6.0. Si le problème était juste académique, il ne serait pas si grave. Luddites200 et Biofuelwatch Like this: J'aime chargement…