Synthetic Biology index partsregistry.org A synthetic biology approach to shed light onto the black box of the brain | Poster | BioBricks Foundation SB6.0: The Sixth International Meeting on Synthetic Biology Yagiz Alp Aksoy, Suja Mohammed, Paul Pilowsky Australian School of Advanced Medicine, Macquarie University, Sydney, Australia, Australia Neurons play a crucial role in the regulation of cardiovascular and cardiorespiratory systems yet functional roles of different neuronal phenotypes remain unclear. In order to elucidate mechanisms underlying many neurological and cardiovascular disorders, a better understanding of the functional and the physiological role of specific neurons is crucial. Here we describe an entirely novel synthetic biology approach for selectively investigating the identification, function and regulation of different types of neurons by expressing genes encoding fluorescent proteins, ribosome inactivating proteins and light-activated ion channels under the control of synthetically engineered neuron-specific promoters.
Synthetic biology Synthetic biology is the design and construction of biological devices and systems for useful purposes. It is an area of biological research and technology that combines biology and engineering, thus often overlapping with bioengineering and biomedical engineering. It encompasses a variety of different approaches, methodologies, and disciplines with a focus on engineering biology and biotechnology. The advance of synthetic biology relies on several key enabling technologies provided at ever increasing speed and lower cost. DNA sequencing, fabrication of genes, modeling how synthetic genes behave, and precisely measuring gene behavior are essential tools in synthetic biology. Geneticists have found a number of gene sequences which correspond to differing traits in organisms; these individual gene sequences have been developed and incorporated into DNA similar to genetic "lego" blocks. History Let me now comment on the question "what next". Perspectives Biology
Biologie synthétique Un article de Wikipédia, l'encyclopédie libre. La biologie synthétique est un domaine scientifique combinant biologie et principes d'ingénierie dans le but de concevoir et construire (« synthétiser ») de nouveaux systèmes et fonctions biologiques. Objectifs[modifier | modifier le code] Les objectifs de la biologie synthétique sont de deux types : Tester et améliorer notre compréhension des principes gouvernant la biologie (apprendre en construisant).Construire de façon fiable des organismes accomplissant des fonctions biologiques complexes répondant à diverses applications (énergie, santé par exemple). Concepts[modifier | modifier le code] Modifier le vivant pose aussi des questions philosophiques et éthiques nouvelles et complexes, en relançant la question de la brevetabilité du vivant ou de ses produits et plus généralement de la propriété intellectuelle. Histoire[modifier | modifier le code] Première génération : les années 1900[modifier | modifier le code]
BioBricks Foundation Edge Master Class 2009 THE CURRENT CATALOG OF LIFE By Ed Regis In their futuristic workshops, the masters of the Synthetic Genomics, Craig Venter and George Church, play out their visions of bacteria reprogrammed to turn coal into methane gas and other microbes programmed to create jet fuel 14. Synthetic genomics, the subject of the conference, is the process of replacing all or part of an organism's natural DNA with synthetic DNA designed by humans. The specter of "biohackers" creating new infectious agents made its obligatory appearance, but synthetic genomic researchers are, almost of necessity, optimists. Church and his Harvard lab team have already programmed bacteria to perform each of these functions separately, but they have not yet connected them all together into a complete and organized system. But tumor-killing microbes were only a small portion of the myriad wonders described by Church. Church is also founder and head of the Personal Genome Project, or PGP. [ Permalink ]
Getting Ready for Synthetic Biology Since the completion of the Human Genome Project in 2003, scientists have expanded their knowledge of how living cells work with new approaches including genomics, proteomics, and systems biology. Yet it is another development--the ability not only to understand but also to synthesize genes at a speed and cost unthinkable just a few years ago--that has spurred, arguably, the greatest paradigm shift in recent biology: Today, many scientists are not content merely to analyze and understand life. They want to create it. Synthetic biology, the synthesis of biological components and devices and the redesign or creation of new life forms, has enormous potential. John Glass, a senior microbiologist in the synthetic biology group at the J. Today, synthetic biology is still in its infancy. A Multidisciplinary Approach to Life Brooke Dill, JCVI John Glass At least as important as the field you come from is a willingness to meet other disciplines halfway. A Field in Synthesis Courtesy, Andrés Moya
Synthetic biology could be big boost to interplanetary space travel Genetically engineered microbes could help make manned missions to Mars, the moon and other planets more practical, according to a new analysis by UC Berkeley and NASA scientists. In the cover story of today’s issue of the Journal of the Royal Society Interface, four bioengineers describe how synthetic biology – what some have termed “genetic engineering on steroids” – could allow space travelers to use microbes to produce their own fuel, food, medicines and building materials from raw feedstocks readily available on Mars or the moon, instead of carrying all supplies aboard the spacecraft or making them at the destination with conventional non-biological methods. “Our analysis indicates that (synthetic biology) has a good chance of being a disruptive space technology by providing substantial savings over current techniques,” said first author Amor Menezes, a postdoctoral scholar in UC Berkeley’s California Institute for Quantitative Biosciences (QB3). Supplies for a 916-day mission