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Research and science behind COVID-19

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Could an $800 air filter be a cheap fix for the threat of airborne COVID in hotel quarantine? How do you stop COVID-19 spreading through the air in hotel quarantine?

Could an $800 air filter be a cheap fix for the threat of airborne COVID in hotel quarantine?

Key points: Concerns continue to be raised over the role of ventilation in the spread of COVID-19 in hotel quarantine An assessment of each of the hotels in Victoria's quarantine program is now underway following the latest cluster in MelbourneOne mechanical engineer proposes air purifiers could be a cost-effective way of reducing the risk of airborne viruses That's the big question state health authorities are grappling with after multiple cases of the virus jumping from infected hotel quarantine guests to workers in cities across Australia — sometimes without a clear chain of transmission being identified.

The latest hotel quarantine cluster in Melbourne has Victorian health authorities vowing to get to the bottom of the role that ventilation played in spreading the virus. How air is escaping from rooms His experiments are simple — he fills a room with smoke and then watches for where it escapes, and how quickly. COVID-19, Hendra and SARS: How scientists trace viruses through animals to their source. The first mission to Wuhan in search of the source of SARS-CoV-2 — the virus that causes COVID-19 — wrapped up this week.

COVID-19, Hendra and SARS: How scientists trace viruses through animals to their source

More than a dozen experts from around the world, including epidemiologists, veterinarians, medical doctors and virologists, spent the past fortnight looking for clues to the virus's origins. Last night, at a press conference, World Health Organization food safety and animal diseases expert Peter Ben Embarek said the coronavirus is unlikely to have leaked from a Chinese lab, and most probably jumped to humans via an intermediary species. And that fact-finding mission will be the first of quite a few, if previous outbreaks are anything to go by. COVID-19 is the latest in a long line of zoonotic diseases — infections that started in animals, but spilled into the human population. Sometimes scientists can search for years and still not find a definitive primary reservoir, as has been the case with Ebola (so far). WHO team arrives in Wuhan to investigate pandemic origins. WUHAN, China (AP) — A global team of researchers arrived Thursday in the Chinese city where the coronavirus pandemic was first detected to conduct a politically sensitive investigation into its origins amid uncertainty about whether Beijing might try to prevent embarrassing discoveries.

WHO team arrives in Wuhan to investigate pandemic origins

The 10-member team sent to Wuhan by the World Health Organization was approved by President Xi Jinping’s government after months of diplomatic wrangling that prompted an unusual public complaint by the head of the WHO. Scientists suspect the virus that has killed 1.9 million people since late 2019 jumped to humans from bats or other animals, most likely in China’s southwest. The ruling Communist Party, stung by complaints it allowed the disease to spread, says the virus came from abroad, possibly on imported seafood, but scientists reject that.

Fauci: US taking hard look at variant of coronavirus. WASHINGTON (AP) — U.S. health officials believe the coronavirus mutation that set off alarms in parts of Britain is no more apt to cause serious illness or be resistant to vaccines than the strain afflicting people in the United States but it still must be taken “very seriously,” the government’s top infectious disease expert said Sunday.

Fauci: US taking hard look at variant of coronavirus

Dr. Anthony Fauci endorsed the decision of U.S. officials to require negative COVID-19 tests before letting people from Britain enter the U.S. He declined to weigh in on whether that step should have been taken sooner. The COVID Science Wars. When Max von Pettenkofer shot himself to death in 1901, he left behind a storied career as a hygienist and bitter opponent of Robert Koch, the German physician and microbiologist who discovered the cholera bacillus, Vibrio cholerae.

The COVID Science Wars

Von Pettenkofer, the founder of the Institute of Hygiene in Munich, disputed Koch’s germ theory of disease, which held that a germ is both necessary and sufficient to cause illness. Von Pettenkofer asserted that germs could only cause disease in the presence of a “local” or environmental factor. The battle between the two men exploded into a bitter divide over the question of the infectivity of cholera.

Koch and his fellow contagionists maintained that the bacterium was spread through the water. Von Pettenkofer and his localists believed that cholera was inhaled as a miasma, which arose from earth contaminated by sewage. Advocates on both sides have dug in, hurling dismissive and vitriolic attacks at individuals in the other camp. Virus that causes COVID-19 survives up to 28 days on surfaces, Australian scientists find - ABC News. The coronavirus that causes COVID-19 can live for up to 28 days on surfaces such as mobile phone screens and ATMs — much longer than previously thought — new Australian research has found.

Virus that causes COVID-19 survives up to 28 days on surfaces, Australian scientists find - ABC News

Key points: The virus survives on most surfaces for about six to seven days before starting to lose potencyOn some surfaces, such as glass and paper banknotes, the virus lasts for longer than a monthPeople can be infected if they touch a contaminated surface then touch their face, nose or mouth CSIRO scientists tested the SARS-CoV-2 virus to see how long it survived on surfaces such as cotton, paper, stainless steel, glass and vinyl. Trevor Drew, director of the Australian Centre for Disease Preparedness, said the research team used the same amount of virus that would be found in someone who was infected. "It's important to know how long this virus can last so we know how often we need to disinfect things and what sort of risk common surfaces pose," Professor Drew said.

Murdoch Children's Research Institute studies family with coronavirus to find out why their children were immune - ABC News. Victorian couple Leila Sawenko and Tony Maguire were shocked when they contracted COVID-19 after travelling interstate for their friends' wedding in March this year.

Murdoch Children's Research Institute studies family with coronavirus to find out why their children were immune - ABC News

Key points: Doctors and scientists at Melbourne's Royal Children's Hospital and the Murdoch Children's Research Institute studied why three children did not get seriously ill with COVID-19The study's findings were published in medical journal Nature Medicine They showed routine testing with nasal and throat swabs may not identify all children who have been exposed to coronavirus Initially they both felt fine before developing mild symptoms. "It wasn't until a week later after we had returned from Sydney that we did start to feel [like we had a] hangover meets jetlag — very foggy headed and a little bit more lethargic than normal," Ms Sawenko said. Back home, they felt sure they would pass on the virus to their three young children, aged six, seven and nine. What is COVID-19 rapid testing, and should we be using it in Australia? - ABC News. They're portable, scalable, and easy to use — and most importantly, can deliver a result in just 15 minutes.

What is COVID-19 rapid testing, and should we be using it in Australia? - ABC News

COVID-19 rapid tests, though considered less accurate than the widely used PCR tests, offer the possibility of testing more people with fewer resources in less time. Just this week, one-hour rapid COVID-19 tests were introduced at Heathrow airport in London as a way to screen passengers as healthy before they travel. So, could they be used as a screening tool in Australia to potentially reopen workplaces, community events and even borders? Should I get tested? What if I don't have symptoms? Will it hurt? Your COVID-19 testing questions answered - ABC News. It's no secret that COVID-19 testing is crucial to get control back over the virus situation in Australia. From the number of people getting tested, to the way that data is reported, to exactly how it physically feels, there's no shortage of questions about COVID-19 tests.

If you're still not sure about getting tested and how it works, we've answered some frequently asked questions right here. How do they test for coronavirus, how long does it take and where do you go to get tested? - ABC News. Not everyone who wants a COVID-19 test will get one.

How do they test for coronavirus, how long does it take and where do you go to get tested? - ABC News

Australia doesn't have enough to go around, so doctors are being asked to limit tests to those most likely to test positive. These include people who: Have recently been overseasHave been in contact with a known caseHave been hospitalised with pneumoniaAre frontline health workersAnd, as of Friday, aged care workers If you're worried you might have COVID-19, Queensland Health has created a quiz you can take (regardless of which state you're in) to find out what you should do.

But don't be surprised if the advice changes regularly. I started a coronavirus testing lab in India. This is what it's like - ABC News. Virologist Prasad Deshpande works in one of India's COVID-19 testing labs.

I started a coronavirus testing lab in India. This is what it's like - ABC News

Every day, he supervises the processing of thousands of COVID-19 swabs, as the country starts coming down from its peak of nearly 100,000 new cases a day. He shared his story with the ABC. When looking at impact of coronavirus, we can't forget the long-term health effects - ABC News. It can be tempting to think of COVID-19 patients as falling into one of two categories. Category 1: young, otherwise healthy individuals who experience mild symptoms and recover at home. Category 2: older people and people with pre-existing health conditions who become seriously ill and go to hospital.

While it's true that there is a spectrum of risk when it comes to severity of disease, it's become increasingly clear that not everyone fits neatly into one of these categories. For many people, the labels of "mild" or "severe", "sick" or "recovered" are blurred by their experience of ongoing, sometimes debilitating symptoms weeks or months after they first were infected. Both anecdotal reports and a growing body of research suggest persistent fatigue, breathlessness, "brain fog" and muscle aches, among other symptoms, are plaguing people some time after their infection has cleared.

So what do we know about the lingering health effects of coronavirus, and how concerned should we be? COVID-19 effects can be persistent and serious say doctors suffering 'long COVID' - ABC News. Nathalie MacDermott is no stranger to deadly diseases. She's worked on the front line of the Ebola epidemic in Liberia, Cholera in Haiti, and this year, treating children critically ill with COVID-19 in London. But now she's fighting on a more personal front line. Severe acute respiratory syndrome coronavirus - Patent US-2006257852-A1. ACP Journals. Key Summary Points Respiratory transmission is the dominant mode of transmission. Vertical transmission occurs rarely; transplacental transmission has been documented. Cats and ferrets can be infected and transmit to each other, but there are no reported cases to date of transmission to humans; minks transmit to each other and to humans.

Victoria could have eliminated Covid in six weeks by entering stage-four lockdown in July, analysis shows. Elimination of Covid-19 has been found to have been achievable in Victoria within six weeks had the state gone into stage-four lockdown with mandatory wearing of masks – but without curfews or 5km travel restrictions – immediately from 9 July, when there were 860 active cases of the virus in the state. The modelling analysis published in the Medical Journal of Australia (MJA) on Monday also says it was a missed opportunity that “an expert advisory group on elimination was not convened, limiting the capacity for an optimal evidence-informed policy response”. From 9 July, metropolitan Melbourne and the Mitchell shire re-entered stage-three lockdown. Victorians were told the measures would last six weeks. However, a more stringent stage-four lockdown was introduced to metropolitan Melbourne on 2 August, when department and hardware stores were closed, and curfew, travel limits and outdoor exercise limits were introduced.

What have one million deaths taught us about COVID-19 and how to treat it? - ABC News. In the beginning, we knew almost nothing about the disease sweeping the world. COVID-19 Resource Centre. Face shields ineffective at trapping aerosols, says Japanese supercomputer. Plastic face shields are almost totally ineffective at trapping respiratory aerosols, according to modelling in Japan, casting doubt on their effectiveness in preventing the spread of coronavirus. A simulation using Fugaku, the world’s fastest supercomputer, found that almost 100% of airborne droplets of less than 5 micrometres in size escaped through plastic visors of the kind often used by people working in service industries.

Experts warn coronavirus may cause 'wave' of neurological conditions including Parkinson's disease - ABC News. Experts warn coronavirus may cause 'wave' of neurological conditions including Parkinson's disease - ABC News. Long-term health impacts of coronavirus to be addressed in new study. Southampton is part of a new £8.4 million study to investigate the long-term health impacts of COVID-19 on hospitalised patients. Coronavirus: 60,000 may have 'long Covid' for more than three months – UK study. Up to 60,000 people in the UK may have been suffering from “long Covid” for more than three months, unable to get the care they need to recover from prolonged and debilitating symptoms.

Tim Spector, a professor of genetic epidemiology at King’s College London who runs the app-based Covid symptom study, said around 300,000 people had reported symptoms lasting for more than a month. A minority have been suffering for longer; up to 60,000 people have reported having symptoms for more than three months. Some cases are mild, but others are seriously debilitating, with breathlessness and fatigue. Some people have had to use wheelchairs. Vaccine by Nov. 3? Halted study explains just how unlikely. WASHINGTON (AP) — The suspension of a huge COVID-19 vaccine study over an illness in a single participant shows there will be “no compromises” on safety in the race to develop the shot, the chief of the National Institutes of Health told Congress on Wednesday. AstraZeneca has put on hold studies of its vaccine candidate in the U.S. and other countries while it investigates whether a British volunteer’s illness is a side effect or a coincidence.

“This ought to be reassuring,” NIH Director Dr. A Supercomputer's Covid-19 Analysis Yields a New Way to Understand the Virus. The coronavirus is mutating, just like most viruses, but the effect isn't as pronounced as some headlines suggest - ABC News. Special Issue : SARS-CoV2 and COVID-19 Outbreak: Lessons, Burning Points and Perspectives. Could we cure coronavirus? Coronavirus covid 19 are cloth face masks likely to provide protection against covid 19 0. COVID-19: Considerations for Wearing Cloth Face Coverings. CDC recommends that people wear cloth face coverings in public settings and when around people who don’t live in your household, especially when other social distancing measures are difficult to maintain.Cloth face coverings may help prevent people who have COVID-19 from spreading the virus to others.Cloth face coverings are most likely to reduce the spread of COVID-19 when they are widely used by people in public settings.Cloth face coverings should NOT be worn by children under the age of 2 or anyone who has trouble breathing, is unconscious, incapacitated, or otherwise unable to remove the mask without assistance.

Evidence for Effectiveness of Cloth Face Coverings Cloth face coverings are recommended as a simple barrier to help prevent respiratory droplets from traveling into the air and onto other people when the person wearing the cloth face covering coughs, sneezes, talks, or raises their voice. This is called source control. Who Should Wear A Cloth Face Covering? Is the airborne route a major source of coronavirus transmission?

'No bare bottoms!': Norman Swan weighs in on corona-farts - Coronacast - ABC Radio. Norman Swan: Hello, this is Coronacast, a podcast all about the novel coronavirus. I'm physician and journalist Dr Norman Swan. Air Conditioning suspected to play major role in coronavirus spread. It is Time to Address Airborne Transmission of COVID-19. Victorians, and anyone else at risk, should now be wearing face masks. Here's how to make one. Follow the Coronavirus Outbreak. Fait désormais partie de Verizon Media. Coronavirus: Scientists warn COVID-19 is spread through airborne transmission. Coronavirus world: New version of COVID-19 spreads faster.

A new swine flu strain discovered in China has 'pandemic potential' Prof Dolores Cahill — Explosive Debunking of the Corona Narrative – Real Corona News. Covid-19: Lancet retracts paper that halted hydroxychloroquine trials. : The mystery of asymptomatic 'silent spreaders' RACGP - Are reports of coronavirus ‘reinfection’ a cause for concern? Will Covid-19 mutate into a more dangerous virus? Experts Finally Declare Imperial College Coronavirus Model That Predicted 2.2M Dead In U.S. ‘Totally Unreliable’

Hydroxychloroquine: Trump's Covid-19 'cure' increases deaths, global study finds. Search of: COVID-19 - List Results. Critique of hydroxychloroquine studies to date – ASCOT: The Australasian COVID-19 Trial. Features, Evaluation and Treatment Coronavirus (COVID-19) - StatPearls - NCBI Bookshelf. COVID-19 pathophysiology: A review. Mirabai twice thought she was clear of COVID-19. But she has just returned a third positive test - ABC News. COVID-19 is like three different diseases, says New York doctor, from flu-like illness to severe reactions and rare children's syndrome - ABC News. Thousands of Covid-19 cases missed due to late warning on smell loss, say experts.

Erinbromage. Scientists concerned that coronavirus is adapting to humans. COVID-19 leaking from Wuhan laboratory is the ‘only plausible explanation’ Temporal dynamics in viral shedding and transmissibility of COVID-19. UK scientists hit back at attempts to discredit scientific basis for lockdown. Researchers Map Structure of Coronavirus "Spike" Protein. Coronaviruses - Medical Microbiology - NCBI Bookshelf. Coronavirus explainer animation video showing its Mechanism of Action. Here Are the First Images of How Coronavirus Replicates in Cells.

COVID-19: The immune system can fight back. Coronavirus symptoms start about five days after exposure, Johns Hopkins study finds. Professor Peter Piot, Director of the London School of Hygiene and Tropical Medicine. Online Panel Discussion. Coronavirus: the first three months as it happened. Fighting the invisible enemy: What these images reveal about the coronavirus. Centre for Tropical Medicine and Global Health @Oxford: Epidemic Diseases Research Group. Coronavirus: medical experts denounce Trump's theory of 'disinfectant injection' Coronavirus detected on particles of air pollution. An interactive web-based dashboard to track COVID-19 in real time - The Lancet Infectious Diseases. Early dynamics of transmission and control of COVID-19: a mathematical modelling study.

Fundamental principles of epidemic spread highlight the immediate need for large-scale serological surveys to assess the stage of the SARS-CoV-2 epidemic. Feasibility of controlling COVID-19 outbreaks by isolation of cases and contacts. Using a delay-adjusted case fatality ratio to estimate under-reporting  The effect of control strategies to reduce social mixing on outcomes of the COVID-19 epidemic in Wuhan, China: a modelling study. COVID-19 and Italy: what next? - The Lancet. Faculty of Medicine. PLOS Collections: Article collections published by the Public Library of Science. Early Transmissibility Assessment of a Novel Coronavirus in Wuhan, China by Maimuna S. Majumder, Kenneth D. Mandl. COVID-19 vaccine tracker. First in Human: Covid-19 Vaccines & Tales of Phase 1 Clinical Trials Past.

The outbreak of SARS-CoV-2 pneumonia calls for viral vaccines. COVID-19 Registered Trials - and analysis - CEBM. Therapeutic Options for COVID-19 Patients. A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19. Use of anti-viral drugs to reduce COVID-19 transmission. Welcome — RECOVERY Trial. WHO: Clinical management of severe acute respiratory infection when COVID-19 is suspected. Some Blood Types May Be Slightly More Susceptible to COVID-19, Paper Suggests. Relationship between the ABO Blood Group and the COVID-19 Susceptibility. Evidence of SARS-CoV-2 Infection in Returning Travelers from Wuhan, China. Transmission of 2019-nCoV Infection from an Asymptomatic Contact in Germany. Temporal dynamics in viral shedding and transmissibility of COVID-19. Diamond Princess Cruise ship – new estimates highlight the successes and failures of the COVID-19 quarantine.

SARS-CoV-2 Infection in Children. Incubation period of 2019 novel coronavirus (2019-nCoV) infections among travellers from Wuhan, China, 20-28 January 2020. - PubMed - NCBI. Homemade hand sanitiser recipes that could help protect against coronavirus.