The EMA covid-19 data leak, and what it tells us about mRNA instability. Leaked documents show that some early commercial batches of Pfizer-BioNTech’s covid-19 vaccine had lower than expected levels of intact mRNA, prompting wider questions about how to assess this novel vaccine platform, writes Serena Tinari As it conducted its analysis of the Pfizer-BioNTech covid-19 vaccine in December, the European Medicines Agency (EMA) was the victim of a cyberattack.1 More than 40 megabytes of classified information from the agency’s review were published on the dark web, and several journalists—including from The BMJ—and academics worldwide were sent copies of the leaks.
They came from anonymous email accounts and most efforts to interact with the senders were unsuccessful. None of the senders revealed their identity, and the EMA says it is pursuing a criminal investigation. T-Cell Screening Test Launched to Detect Prior Covid Infections. Rare blood auto immune disorder appearing in very small amount of COVID vaccine recipients.
“If we recognize it early, it's treatable.
It shouldn't hold us from encouraging them to get the vaccine.” NEW ORLEANS — The CDC, the FDA, and the makers of the Pfizer and Moderna COVID-19 vaccines, are looking into reports of a rare blood disorder in a small number of people who got the vaccine. After more than 31 million people in the U.S. have gotten a COVID vaccine, three dozen cases of a rare blood auto immune disorder, causing one death, have been reported.
The History of the Pharma Cartel. 1911, May 15 The Supreme Court of the U.S. finds John Rockefeller and his Trust guilty of corruption, illegal business practices and racketeering.
As a result of this decision, the entire Rockefeller Standard Oil-Trust, the world’s largest corporation of its time, was sentenced to be dismantled. But Rockefeller was already above the Supreme Court and did not care about this decision. In order to disperse public and political pressure on him and other robber-barons, Rockefeller uses a trick called “philanthropy”, whereby the illegal gains from his robber-practices in the oil business are used to launch the Rockefeller Foundation. This tax haven was used to strategically take over the health care sector in the U.S.. The Rockefeller Foundation was the front organization for a new global business venture of Rockefeller and his accomplices. This was also the time when the first vitamins were discovered.
New Study By Dr. Steven Quay Concludes that SARS-CoV-2 Came from a Laboratory. SEATTLE, Jan. 29, 2021 /PRNewswire/ -- A paper was published today by Dr.
Steven Quay, M.D., PhD., CEO of Atossa Therapeutics, Inc. (NASDAQ: ATOS), entitled, “A Bayesian analysis concludes beyond a reasonable doubt that SARS-CoV-2 is not a natural zoonosis but instead is laboratory derived.” Asymptomatic transmission of covid-19. What we know, and what we don’t The UK’s £100bn “Operation Moonshot” to roll out mass testing for covid-19 to cities and universities around the country raises two key questions.
How infectious are people who test positive but have no symptoms? And, what is their contribution to transmission of live virus? Information Notice for IVD Users 2020/05. Product type: Nucleic acid testing (NAT) technologies that use polymerase chain reaction (PCR) for detection of SARS-CoV-2 Date: 13 January 2021 WHO-identifier: 2020/5, version 2 Target audience: laboratory professionals and users of IVDs.
Masks don’t stop Covid but they do spread fear. FOR ages I’d been walking into supermarkets without wearing a mask.
Staff had never asked me to wear one and allowed me to go about my business. That all changed the other week on my birthday, despite there having been no Covid outbreaks at any of the shops I have visited that I am aware of, and no evidence that I was a threat to the welfare of their employees. I had driven with my girlfriend to a supermarket to buy some items she needed – literally the most exciting thing many of us can do right now, so a birthday treat! But the guards outside the store wrecked that by telling us that we could not go in together. I controlled my temper and waited outside for my girlfriend while she shopped. In the evening, we went to another supermarket closer to home to buy some drinks to celebrate my birthday, and this experience was worse.
To Spread or Not to Spread SARS-CoV-2—Is That the Question? The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has upended society in many ways.
The tragic and rising number of deaths we continue to see throughout the world, the overloaded hospitals, the devastated economies1—all of these appropriately garner daily front-page headlines. Are Face Masks Effective? The Evidence. – Swiss Policy Research. Updated: January 2021; Published: July 2020Share on: Twitter / Facebook Fourni par Traduction An overview of the current evidence regarding the effectiveness of face masks.
All About Masks. All About Masks. Informed consent disclosure to vaccine trial subjects of risk of COVID-19 vaccines worsening clinical disease. Aims of the study: Patient comprehension is a critical part of meeting medical ethics standards of informed consent in study designs.
The aim of the study was to determine if sufficient literature exists to require clinicians to disclose the specific risk that COVID-19 vaccines could worsen disease upon exposure to challenge or circulating virus. Methods used to conduct the study: Published literature was reviewed to identify preclinical and clinical evidence that COVID-19 vaccines could worsen disease upon exposure to challenge or circulating virus. Lipid Nanoparticles: A Novel Approach for Brain Targeting. Background: Brain is a delicate organ, separated from general circulation and is characterized by the presence of relatively impermeable Blood Brain Barrier (BBB). The BBB maintains homeostasis in the brain thus restricting the entrance of foreign bodies and several molecules from reaching the brain.
As a result several promising molecules do not reach the target site and fail to produce in vivo response. Nevertheless, lipid nanoparticles are taken up readily by the brain because of their lipophilic nature. The bioacceptable and biodegradable nature of lipid nanoparticles makes them less toxic and suited for brain targeting. The relative infectivity of the new UK variant of SARS-CoV-2 – Nicholas Lewis. A pdf copy of this article is available here Key points A new variant, B.1.1.7, of the SARS-CoV-2 virus has recently spread rapidly in EnglandThe public health agency’s best estimate of B.1.1.7’s weekly growth rate advantage is 1.51xThey mis-convert this in a reproduction number ratio of 1.47; converting appropriately gives 1.25Confident claims by the UK government scientific advisers that the higher growth of B.1.1.7 is due to increased transmissibility are misplaced; it could be partly of wholly due to other factors1.1.7 has not shown a greater growth rate advantage than two previous variants did, both of which are now thought to have no greater transmissibility than previously existing variantsThere is little evidence that B.1.1.7 is more virulent, or likely to be resistant to existing vaccines Introduction The apparent rapid growth in England of a new variant of the SARS-CoV-2 virus that causes COVID-19 has led to dire warnings by those advising the UK government.
Figure 1. Figure 2. Antibody Status and Incidence of SARS-CoV-2 Infection in Health Care Workers. Has the HPV vaccine approval ushered in an era of over-prevention? SAGE conflicts of interest – Zoë Harcombe. Executive summary * As late as March 11th, 2020, the UK government and medical officers issued practical and minimally disruptive advice to combat the spread of the novel coronavirus. * On March 16th, the now infamous Neil Ferguson/Imperial College paper was published predicting over 500,000 deaths in the UK and 2.2 million in the US if suppression measures were not introduced. * Stricter measures were announced on the day that paper was published, and the first UK lockdown was announced a week later, on March 23rd.
US states variously followed suit. * The committee that has been advising the government throughout this period is called the Scientific Advisory Group for Emergencies (SAGE) . * This week’s note examines the key influencers on SAGE and their conflicts of interest: – Organisations invested in vaccines make money from vaccines. Acclaimed pharma professor thrown in psychiatric hospital for questioning official COVID narrative.
© Begir/ShutterstockPsychiatric hospital Le Mas Careiron in Uzès where Fourtillan is held against his will. Early on December 10, Jean-Bernard Fourtillan, a French retired university professor known for his strong opposition to COVID-19 vaccines such as those presently being distributed in the U.K., was taken from his temporary home in the south of France by a team of "gendarmes" — French law enforcement officers under military command — and forcibly placed in solitary confinement at the psychiatric hospital of Uzès. His mobile phones were taken from him, and at the time of writing, he had not been allowed to communicate with the outside world. The order for his internment appears to have been issued by the local "préfet," the official representative of the French executive.
Use of surgical face masks to reduce the incidence of the common cold among health care workers in Japan: a randomized controlled trial - PubMed. Background: Health care workers outside surgical suites in Asia use surgical-type face masks commonly. Prevention of upper respiratory infection is one reason given, although evidence of effectiveness is lacking. Methods: Health care workers in a tertiary care hospital in Japan were randomized into 2 groups: 1 that wore face masks and 1 that did not. They provided information about demographics, health habits, and quality of life. Participants recorded symptoms daily for 77 consecutive days, starting in January 2008. Public health journal “seeking further expert advice” on January paper about COVID-19 PCR testing by high-profile virologist. After a petition from nearly two dozen people in Europe, the United States and Asia, a public health journal says it is investigating an article it published last January about a way to detect the virus that causes COVID-19.
Advice on the use of masks in the community, during home care and in healthcare settings in the context of the novel coronavirus (COVID-19) outbreak. Contact Settings and Risk for Transmission in 3410 Close Contacts of Patients With COVID-19 in Guangzhou, China : A Prospective Cohort Study - PubMed. Review report Corman-Drosten et al. Eurosurveillance 2020 – CORMAN-DROSTEN REVIEW REPORT.
November 27, 2020 This extensive review report has been officially submitted to Eurosurveillance editorial board on 27th November 2020 via their submission-portal, enclosed to this review report is a retraction request letter, signed by all the main & co-authors. First and last listed names are the first and second main authors.
All names in between are co-authors. Head of Pfizer Research: Covid Vaccine is Female Sterilization – Health and Money News. Study: COVID-19 Vaccine Can Destroy Your Immune System. Published on November 17, 2020. Annrcse01509 0009. FDA ignores science in expanding remdesivir to treat COVID-19. Remdesivir is reportedly showing promise, but there's no guarantee the initial reports will lead to a commercially available treatment for COVID-19. USA TODAY The U.S. Food and Drug Administration late Friday allowed the drug remdesivir to be used on all patients hospitalized with COVID-19, although no published research supports such widespread use.
The approval allows doctors freedom to prescribe the antiviral earlier. Coronavirus among children: Major coronavirus study in Spanish summer camps shows low transmission among children. New approach to recording COVID deaths. A new study by academics at the Universities of Loughborough and Sheffield, and economic consultants at Economic Insight, seeks to provide a more statistically robust approach to the question: “How many deaths in England and Wales are due to COVID-19?”.
‘Pupils pose little risk of spreading Covid’ Faith in Quick Test Leads to Epidemic That Wasn’t. “It’s a problem; we know it’s a problem,” Dr. Perl said. “My guess is that what happened at Dartmouth is going to become more common.” Many of the new molecular tests are quick but technically demanding, and each laboratory may do them in its own way. These tests, called “home brews,” are not commercially available, and there are no good estimates of their error rates. But their very sensitivity makes false positives likely, and when hundreds or thousands of people are tested, as occurred at Dartmouth, false positives can make it seem like there is an epidemic. “You’re in a little bit of no man’s land,” with the new molecular tests, said Dr. Keeping schools open had no impact on contagion, Swedish study suggests. Oregon COVID 19 Update 07 21 2020 FINAL. Masks Fail to Filter Virus in Coughing COVID-19 Patients - Critical Care - mobile.Hospimedica.com.
Why Face Masks Don’t Work: A Revealing Review - Oral Health Group. Immunity to COVID-19 is probably higher than tests have shown. Melatonin Inhibits COVID-19-induced Cytokine Storm by Reversing Aerobic Glycolysis in Immune Cells: A Mechanistic Analysis. The Amygdala is a Chemosensor that Detects Carbon Dioxide and Acidosis to Elicit Fear Behavior.