Magnesium and Malic Acid. Co-enzyme Q10. NADH. PQQ. L-Carnitine. Living with ME/CFS: Sourcing cheap supplements – Shoutout about ME. For a number of perfectly legitimate reasons—restricted mobility, limited finances and a lack of mainstream treatment options—many me/cfs patients are forced to consider alternatives for symptom relief.
For some, the growing availability, accessibility and affordability of vitamin and herbal supplements on the internet is an attractive option, with the rider that the efficacy and safety of most supplements will vary from patient to patient. ME/CFS Roadmap, an extensive resource on diagnosing and treating me/cfs has some useful tips for patients wishing to go down this road.
Suppliers like iHerb, Prohealth, Vitacost, or HealthMonthly are well-known for their very low prices. eBay also usually has excellent supplement prices. In Australia, delivery from overseas suppliers can often be faster than from local suppliers and certainly cheaper – even when currency disparities are factored in. Consider buying in bulk Some bulk powder supplement suppliers include: Further Reading. WELCOME. Vitamin D status in chronic fatigue syndrome/myalgic encephalomyelitis: a cohort study from the UK. BMJ Open. 2017 Nov 8;7(11):e015296. doi: 10.1136/bmjopen-2016-015296.Vitamin D status in chronic fatigue syndrome/myalgic encephalomyelitis: a cohort study from the North-West of England.Earl KE1, Sakellariou GK1,2, Sinclair M1, Fenech M1,3, Croden F4, Owens DJ5, Tang J6, Miller A3, Lawton C4, Dye L4, Close GL5, Fraser WD6, McArdle A1, Beadsworth MBJ1,3.Author informationAbstractOBJECTIVE: Severe vitamin D deficiency is a recognised cause of skeletal muscle fatigue and myopathy.
The aim of this study was to examine whether chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is associated with altered circulating vitamin D metabolites. DESIGN: Cohort study. SETTING: UK university hospital, recruiting from April 2014 to April 2015. Master Enzyme Switch Deactivated In Chronic Fatigue Syndrome and Fibromyalgia. Discovering the Immune Benefits of Arabinogalactan. Larch arabinogalactan: clinical relevance of a novel immune-enhancing polysaccharide. Curcumin Boosts AMPK Activation, Prevents Fatty Liver. Product Spotlight: S-Acetyl Glutathione Synergy — Dr Courtney Craig. Low tissue glutathione has been observed in a number of chronic conditions including CFS and fibromyalgia.
Studies have shown improvement in symptoms with restoration of normal glutathione stores. Supplemental glutathione comes in many forms: inhaled, topical creams, intramuscular injection, or intravenous. Oral supplementation is seen as inefficient and has thus far been ineffective at raising tissue stores. A new form of glutathione, the acetylated form, provides optimum absorption and bioavailability with the convenience of oral administration. Choline Helps POTS, Chronic Fatigue Syndrome, and Autoimmune Disorders. Product Spotlight: Kre-Alkalyn — Dr Courtney Craig. Kre-Alkalyn is a patented, next-generation alkaline form of creatine.
Its key features differ from traditional creatine powders due to the fact that it is more alkaline, which enables enhanced support for lactic acid and metabolic acid buffering. Kre-Alkalyn also enables a high concentration of cellular creatine to be absorbed at a lower effective dose without the need for a “loading phase” of high doses. Also, Kre-Alkalyn does not cause water retention and is safe to take daily. Kre-Alkalyn may lessen muscle soreness in fibromyalgia due to lactic acid build-up. A 16-week double-blind, randomized control study in fibromyalgia patients showed creatine supplementation increased intramuscular phosphocreatine content by 80% (more ATP available) and improved lower and upper body muscle function, with some additional effects on general symptoms (3).
The Role of Glutamine in Tissue Rejuvenation. Effects of long-term treatment with quercetin on cognition and mitochondrial function in a mouse mod. Managing Brain and Nerve Health, Oxidative Stress, and Mitochondria in CFS, FM, and Lyme Disease. Brain Atrophy Found in Chronic Fatigue Syndrome. Lithium's Role in Chronic Fatigue Syndrome — Dr Courtney Craig. The trace metal lithum is oft overlooked in terms of nutritional support.
Although not abundant compared to other metals like iron and zinc, lithium plays a key role in several biochemical mechanisms pertinent to chronic illnesses such as fibromyalgia and chronic fatigue syndrome. Lithium is highly concentrated in the diet in eggs, dairy products, beets, and thyme. It has been suggested that as much as 83% of the population is deficient in this metal (1). Neurocognitive Support Most are familiar with prescribable lithium utilized for the treatment of psychological and major depressive disorders. Possible mechanisms surrounding lithium’s cognitive support include its ability to maintain BDNF levels—the crucial neurotropic product recently found severely depleted in CFS. Influence of melatonin on fatigue severity in patients with chronic fatigue syndrome and late melatonin secretion. - PubMed - NCBI.
Living With ME/CFS: Imunovir Update and Inosine. I have been struggling a bit lately because of a shortage of Imunovir, an immune-modulating medication that helps me quite a bit, so I thought I'd give a brief update here and also find out if any of you have any experience with inosine, a generic compound similar to Imunovir.
I looked back at my last post on Imunovir, where I described my experiences with it and how much it has helped me - I was surprised to see that I wrote that over two years ago! So, I am overdue for an update anyway. The quick version is that I am still doing well on Imunovir - in all the ways and for all the reasons I explained in that earlier post. A preliminary study of dehydroepiandrosterone response to low-dose ACTH in chronic fatigue syndrome and in healthy subjects. - PubMed - NCBI. ButyrEn 100 Tabs. Choline Helps POTS, Chronic Fatigue Syndrome, and Autoimmune Disorders. D-Ribose Improves QOL For People with Chronic Fatigue. The use of D-ribose in chronic fatigue syndrome and fibromyalgia: a. Vitamin D and CFS Research Papers. See also: English - advanced Search in your language with Chrome browser add-on powered by Custom Search www.vitamindwiki.com.
Vitamin D May Help Chronic Fatigue. Mending the Mitochondria: Lipid Replacement Therapy for Chronic Fatigue Syndrome — Dr Courtney Craig. Several studies in CFS and fibromyalgia show evidence of increased markers of free radical damage; including DNA oxidation and lipid oxidation (1).
These markers are measured through blood or as urine organic acid metabolites. Excessive nitric oxide is also observed indicating changes in cytokines as the cycle of free radical damage ensues (1). Microbial byproducts generated from dysbiosis may also damage the mitochondria. Excessive hydrogen sulfide produced from microbe overgrowth in the small intestine (SIBO) can damage mitochondrial complexes in a dose-dependent manner similar to the action of cyanide (2). Supplementation with mitochondrial supports are widely utilized by CFS and FM patients. Repair Damaged Mitochondria and Reduce Fatigue Up to 45% Clinical trials have shown that NT Factor® can actually support the repair of damaged cell membranes – in effect reducing the cells’ biological age and restoring mitochondrial ability to generate energy.
This is true whether the reduced energy/fatigue is from an illness like ME/CFS, fibromyalgia, Lyme disease a side effect of chemotherapy, or simply a result of aging. Studies done with severely fatigued patients in each of these populations demonstrated that NT Factor can support reduction of fatigue levels by as much as 45 percent.(1-3) The Story Behind NT Factor. Mitochondria Ignite™ with NT Factor® - 675 mg , 90 medium tablets by ProHealth. Product Spotlight: ProGreens with NT Factor — Dr Courtney Craig.
ProGreens Energy also has the original ingredients found in ProGreens – organic grasses, probiotics, vegetable superfoods, sea vegetables, bee products, and fibers.
These ingredients are excellent binders of unwanted molecules in the gut (e.g. mycotoxins), and provide fibrous substrate to promote healthy gut flora. Sea vegetables also offer an excellent source of iodine for patients with low thyroid function. What makes this product especially useful for ME/CFS and Fibro patients is the addition of the mitochondrial blend NT Factor. Developed by prominent researcher Dr. Garth Nicholson, NT Factor is a patented mitochondrial membrane phospholipid, combining antioxidants and lipid transporters to repair damaged mitochondria (4). NT Factor has been studied in some clinical trials to improve fatigue and energy levels. Read more about these studies in a previous blog post. ProGreens NT is gluten free and hypoallergenic. Click here for a FAQ sheet.