100 Diagrams That Changed the World. Since the dawn of recorded history, we’ve been using visual depictions to map the Earth, order the heavens, make sense of time, dissect the human body, organize the natural world, perform music, and even concretize abstract concepts like consciousness and love. 100 Diagrams That Changed the World (public library) by investigative journalist and documentarian Scott Christianson chronicles the history of our evolving understanding of the world through humanity’s most groundbreaking sketches, illustrations, and drawings, ranging from cave paintings to The Rosetta Stone to Moses Harris’s color wheel to Tim Berners-Lee’s flowchart for a “mesh” information management system, the original blueprint for the world wide web.
It appears that no great diagram is solely authored by its creator. Most of those described here were the culmination of centuries of accumulated knowledge. Most arose from collaboration (and oftentimes in competition) with others. Christianson offers a definition: Learning Mind - Expand your mind with lifelong learning. RGS14. Regulator of G-protein signaling 14 (RGS14) is a protein that in humans is encoded by the RGS14 gene.[1] Function[edit] RGS14 is a member of the regulator of G protein signalling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco motif. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits.
Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. Increasing the expression of the RGS14 protein in the V2 secondary visual cortex of mice promotes the conversion of short-term to long-term object-recognition memory.[2] Conversely RGS14 is enriched in CA2 pyramidal neurons and suppresses synaptic plasticity of these synapses and hippocampal-based learning and memory.[3] Interactions[edit] RGS14 has been shown to interact with: References[edit] Further reading[edit] Wellcome: Axon Game. What Your Facebook Account Says About Your Brain. Multitasking:This is your Brain on Media. The Limits of Intelligence.
Santiago Ramón y Cajal, the Spanish Nobel-winning biologist who mapped the neural anatomy of insects in the decades before World War I, likened the minute circuitry of their vision-processing neurons to an exquisite pocket watch. He likened that of mammals, by comparison, to a hollow-chested grandfather clock. Indeed, it is humbling to think that a honeybee, with its milligram-size brain, can perform tasks such as navigating mazes and landscapes on a par with mammals. A honeybee may be limited by having comparatively few neurons, but it surely seems to squeeze everything it can out of them. At the other extreme, an elephant, with its five-million-fold larger brain, suffers the inefficiencies of a sprawling Mesopotamian empire. Signals take more than 100 times longer to travel between opposite sides of its brain—and also from its brain to its foot, forcing the beast to rely less on reflexes, to move more slowly, and to squander precious brain resources on planning each step.
Brain-based learning, ideas, and materials. The Whole Brain Atlas. Focus on Brain Disorders. How to increase serotonin in the human brain without drugs.