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PLoS ONE: Tuberculosis Treatment in HIV Infected Ugandans with C
Background Both HIV and TB cause a state of heightened immune activation. Immune activation in HIV is associated with progression to AIDS. Prior studies, focusing on persons with advanced HIV, have shown no decline in markers of cellular activation in response to TB therapy alone. Methodology This prospective cohort study, composed of participants within a larger phase 3 open-label randomized controlled clinical trial, measured the impact of TB treatment on immune activation in persons with non-advanced HIV infection (CD4>350 cells/mm3) and pulmonary TB.Boing Boing
By Xeni Jardin at 10:19 am Sunday, Apr 8 • 3 Comments • Share This is how it's done. A ring-tailed coati mauls and slurps Easter eggs in Zagreb Zoo April 8, 2012. (REUTERS/Antonio Bronic)
We are fortune here at Science20 to have come across an early work by Gaston Leroux. This manuscript was dated to 1899, suggesting it was an early, discarded draft of the work that later came to be known as "The Phantom of the Opera". Current speculation is Gaston changed the setting at the beheast of his editor. Here, then, is the unabridged transcript of that early draft. It is set in the historic 1899 Paris Academie des Sciences, and begins with the arrival of two new managers to this prosperous yet troubled place. [Secretary] "Welcome, new Branch Heads, to our Paris Laboratory!
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Photo: Joe Pugliese There is one version of Craig Venter’s life story where he would’ve been a dutiful scientist at the National Institutes of Health, a respected yet anonymous researcher in genetics, perhaps. Thankfully, Venter saw that story line developing—and set about making sure it never happened. Instead, in 1992 Venter left the NIH to head the nonprofit Institute for Genomic Research. Six years later he founded Celera Genomics, a brash rival to the NIH project that aimed to sequence the full code of the human genome. Venter had come up with a better technique—known as shotgun sequencing—to get the job done, and it changed the way we translate genetics from proteins into code.
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A man lets off fireworks during a festival in Guangzhou. Chinese alchemists created explosive mixtures in their quest for an elixir of life. Photograph: China Photos/Getty
MSNBC reports that the lack of temperature rise in the last 12 years has convinced environmentalist James Lovelock ( The Gaia Hypothesis) that the climate alarmism wasn’t warranted. From his Wikipedia entry: Writing in the British newspaper The Independent in January 2006, Lovelock argues that, as a result of global warming , “billions of us will die and the few breeding pairs of people that survive will be in the Arctic where the climate remains tolerable” by the end of the 21st century. He has been quoted in The Guardian that 80% of humans will perish by 2100 AD, and this climate change will last 100,000 years.
