Esophageal pH monitoring - Wikipedia. Esophageal pH monitoring is the current gold standard for diagnosis of gastroesophageal reflux disease (GERD).
It provides direct physiologic measurement of acid in the esophagus and is the most objective method to document reflux disease, assess the severity of the disease and monitor the response of the disease to medical or surgical treatment. It can also be used in diagnosing laryngopharyngeal reflux. Background Gut and Brain connection - HPHPA urine test (Depression, Autism, Anxiety etc....) Interesting read for anyone suffering from mental issues.
Wish you all well Bob. "Abstract A compound identified as 3-(3-hydroxyphenyl)-3-hydroxypropionic acid (HPHPA) was found in higher concentrations in urine samples of children with autism compared to age and sex appropriate controls and in an adult with recurrent diarrhea due to Clostridium difficile infections. The highest value measured in urine samples was 7500 mmol/mol creatinine, a value 300 times the median normal adult value, in a patient with acute schizophrenia during an acute psychotic episode. The psychosis remitted after treatment with oral vancomycin with a concomitant marked decrease in HPHPA. Science says gut health controls human behavior. (NaturalHealth365) We’ve all had those ‘gut feelings’ and sometimes make decisions based on those feelings.
Dr. Emeran Mayer, out of UCLA, states that there may be a reason for this phenomenon because gut microbes affect what goes on in our brain. In fact, Dr. Mayer has found that bacteria in our digestive system may help mold brain structure as we’re growing up and possibly influence our moods and behavior. PANDAS: Strep Throat Can Trigger Obsessive Compulsive Disorder in Children.
Karli Bossman was a happy 5-year-old from Clayton, N.C., who loved going to kindergarten -- until one day in 2008, the easy-going child suddenly became obsessive and defiant.
She ripped off her socks and underwear because they "hurt" and insisted on wearing pajamas. And Karli refused to get in the car because she was afraid it would run out of gas. At first, her parents, Kevin and Kelly Bossman, thought the little girl was being bullied, but after checking with her teachers, that was not the case. What was so frightening was how quickly her behavior changed. "All of a sudden she was crying and didn't want to go to school anymore," said her mother, 32-year-old Kelly Bossman. Anxiety In Your Head Could Come From Your Gut. Dr.
James Greenblatt, a Boston-area psychiatrist, had a puzzling case: a teenager arrived in his office with severe obsessive–compulsive disorder (OCD), as well as attention deficit hyperactivity disorder (ADHD) and an array of digestive problems. "Mary's parents had been running around for many years and she'd had a poor response to medicine," said Greenblatt, founder of Comprehensive Psychiatric Resources Inc. in Waltham, Mass. Clostridia — The Great Plains Laboratory, Inc. The Great Plains Laboratory Organic Acids Test is very sensitive and can differentiate between harmful and beneficial bacteria, which is is unique among tests for Clostridia.
It is also the only organic acids test available that measures HPHPA, one of the primary toxic metabolites of Clostridia. In the sample results below, the patient has a high level of HPHPA, but a low level of 4-Cresol, the main marker for C. difficile. Other tests that only measure 4-Cresol, and not HPHPA, would have missed this harmful bacterial overgrowth. Another benefit to The Great Plains Laboratory Organic Acids Test is that it evaluates Clostridia metabolites that can inhibit metabolism of important neurotransmitters. IMMH Registry. Articles Return to article list Usefulness of HPHPA marker in a wide range of neurological, gastrointestinal, and psychiatric disorders by William Shaw, Ph.D.
The dysbiosis marker 3-(3-hydroxyphenyl)-3-hydroxypropionic acid (HPHPA), the predominant dihydroxyphenylpropionic acid isomer in urine, is also measured in the Organic Acids Test offered by The Great Plains Laboratory. This marker was proven by Dr. William Shaw to be due to a combination of human metabolism and the metabolism by a group of Clostridia species, including but not limited to C. difficile. Age of Autism Science Summary: Anxiety, Sensory Over-Responsivity, and Gastrointestinal Problems in Children with Autism Spectrum Disorders. J Abnorm Child Psychol. 2012 Aug 1.
[Epub ahead of print] Anxiety, Sensory Over-Responsivity, and Gastrointestinal Problems in Children with Autism Spectrum Disorders. Mazurek MO, Vasa RA, Kalb LG, Kanne SM, Rosenberg D, Keefer A, Murray DS, Freedman B, Lowery LA. Age of Autism Science Summary: Anxiety, Sensory Over-Responsivity, and Gastrointestinal Problems in Children with Autism Spectrum Disorders. Legal/Illegal List - Breaking the Vicious Cycle. The Scientific Diet for GI Problems, Autism and Other Conditions.
The River to Recovery. Many people with digestive issues have turned to the SCD and GAPS diets to heal the lining of their intestines.
Studies indicate that starches, complex carbohydrates and sugars that are difficult to digest, feed fungi and bacteria in the gut. The Specific Carbohydrate and GAPS diets eliminate the foods that feed these microorganisms, starving the pathogens so that they leave the body. The removal of these things, while also adding probiotics, corrects dysbiosis and is followed by a decrease in intestinal inflammation so the gastrointestinal tract can heal. While the diets seem strict and limiting compared to the standard american diet (SAD) we’re used to, the cycle of malabsorption, maldigestion, inflammation, and food allergies can be corrected using these dietary approaches.