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Gamers Unlock Protein Mystery That Baffled AIDS Researchers For Years

September 19, 2011 10:42am EST In just three weeks, gamers deciphered the structure of a key protein in the development of AIDS that has stumped scientists for years. According to a study published Sunday in the journal Nature Structural & Molecular Biology , the findings could present a significant breakthrough for AIDS and HIV research. Using an online game called Foldit, players were able to predict the structure of a protein called retroviral protease, an enzyme that plays a critical role in the way HIV multiplies. Unlocking the build of the protein could theoretically aid scientists in developing drugs that would stop protease from spreading. “Following the failure of a wide range of attempts to solve the crystal structure of M-PMV retroviral protease by molecular replacement, we challenged players of the protein folding game Foldit to produce accurate models of the protein,” the study reads. http://www.pcmag.com/article2/0,2817,2393200,00.asp#fbid=k1UZOQA3VqO
http://perso.numericable.fr/robert.marty/semiotique/flows_of_signs.htm Robert Marty First European Congress on Cognitive Science ECCS'95, Saint Malo 1995, April To think with accuracy about collective cognition it is necessary to define with precision the subject of this cognition. This latter is not a totality of separate individual subjects constituted by the unique common reference to an object or several objects of knowledge. Individuals communicate, knowledge spreads in human communities to the extent that D.Sperber (1987) has been able to advance the metaphor - perhaps a bit risky - of a "epidemiology of representations" . It concerns of course the capture of cognitive functions that are accomplished by collective entities as groups, enterprises, organizations or institutions (P.

Flows of signs on a network

http://www.news.com.au/travel/news/the-future-is-here-driverless-airport-pods-a-reality/story-e6frfq80-1226141546271

The future is here: Driverless airport pods a reality

Your video will begin in 2 seconds Heathrow airport has rolled out its new driverless transport pods / Heathrow Airport Ltd news.com.au 20 September 2011 Share : Look ma, no driver Your video will play following this advertisement THE future of public transport has finally arrived with Heathrow Airport officially unveiling laser-guided travel pods.
Fear and loathing deep in the forest by Peter Calder, New Zealand Herald If you're not paranoid, you haven't been paying attention. It's an old line, coined half in wry humour, half in deadly earnest, but it has a special pungency for Wellington filmmaker Errol Wright. Wright and co-director Abi King-Jones have spent most of the last three years making Operation 8, a restrained, even sober survey of the October 2007 "anti-terror raids" and their aftermath, that patiently paints a disturbing picture of the use of state force to suppress political dissent. Wright is aware that the undertaking will have attracted close official attention.

Operation 8

http://www.cutcutcut.com/Operation8.html
http://www.asia-pacific-solidarity.net/news/jg_activistscallonagotousewi_100911.htm Activists call on AGO to use Wikileaks cables as new evidence Jakarta Globe - September 10, 2011 Jakarta – Activists from various human rights NGOs urged Attorney General Basrief Arief to challenge a Supreme Court ruling that acquitted the alleged mastermind of the murder of rights activist Munir Said Thalib by using US diplomatic cables recently leaked by whistle-blower website WikiLeaks. The cables, which linked the murder to the National Intelligence Agency (BIN), should have been presented as new evidence to prosecute former BIN deputy chairman Muchdi Purwoprandjono, Choirul Anam from the Solidarity Action Committee for Munir (Kasum) told a press conference on Friday.

Indonesia News Updates - Activists call on AGO to use Wikileaks cables as new evidence

Novel gets to truth of Sabra and Shatila

Israel’s invasion of Lebanon and subsequent 22-year-long occupation has been the focus of three acclaimed Israeli films in recent years: Lebanon , Waltz with Bashir and Beaufort tell the story of this era from the perspective of the occupiers. All young men serving in the Israeli army, the films’ protagonists question their roles in Lebanon. However, this narrative perspective leads the viewer to empathize with the occupier and thus do little other than reinforce a simplistic falsification of Israel’s history as a country always conflicted when waging necessary wars of self-defense. http://electronicintifada.net/content/novel-gets-truth-sabra-and-shatila/3597

List of common misconceptions

http://en.wikipedia.org/wiki/List_of_common_misconceptions This incomplete list is not intended to be exhaustive. This list pertains to current, widely held, erroneous ideas and beliefs about notable topics which have been reported by reliable sources. Each has been discussed in published literature, as has its topic area and the facts concerning it. Note that the statements which follow are corrections based on known facts; the misconceptions themselves are referred to rather than stated. History

MIT Creates New Energy Source

http://www.bestoftheblogs.com/Home/26988 This is some pretty exciting news. It seems that researchers at the Massachusetts Institute of Technology (MIT), one of the most prestigious science and engineering schools in the United States, has created a new energy source -- and it's clean and renewable. The odd thing is that the only way you can see this energy source is with a very powerful microscope, because it is created by using nanotechnology.
http://kk.org/cooltools/ I’ve been driving 4×4 trucks for over 30 years. The trade-off for the weight and truckiness being that I could pick up firewood, haul lumber and sacks of concrete, and go anywhere, any time. I spent 12 years 4-wheeling in Baja. Many trips to the American Southwest (always in spring). Three long trips to British Columbia, shooting pics for Builders of the Pacific Coast . 4-wheeling it across the river to my friend Louie’s house in Mendocino county. I’ve been a truck guy forever.

Cool Tools

http://www.aljazeera.com/indepth/features/2010/10/20101019212440609775.html

US-trained cartel terrorises Mexico - Features

It was a brutal massacre even by the gruesome standards of Mexico’s drug war: 72 migrant workers gunned down by the "Zetas" - arguably the country's most violent cartel - and left rotting in a pile outside a ranch in Tamaulipas state near the US border in late August. The Zetas have a fearsome reputation, but the real surprise comes not in their ruthless use of violence, but in the origins of where they learned the tricks of their bloody trade. Some of the cartel's initial members were elite Mexican troops, trained in the early 1990s by America’s 7th Special Forces Group or "snake eaters" at Ft. Bragg, North Carolina, a former US special operations commander has told Al Jazeera.

Cheat Sheets

Check out MakeUseOf cheat sheets that list shortcuts for a number of essential programs that you probably use on a daily basis. Those will definitely make you more productive. All free. Enjoy!

Senegalese Peanut Soup with Chicken Recipe : Emeril Lagasse

Preheat oven to 400 degrees F. Coat the sweet potatoes with 1 tablespoon of the peanut oil and place in an oven-proof pie tin. Place the pie tin in the oven and roast the sweet potatoes for 50 minutes to 1 hour, or until the potatoes are fully roasted and fork tender.

7 Secrets of the Super Organized

A few years ago, my life was a mess. So was my house, my desk, my mind. Then I learned, one by one, a few habits that got me completely organized. Am I perfect?