Coronavirus Hub: Cell Press

Take Sambucol-Coronovirus Self-Assistance – Part 1 | PSI, Inc. Published on March 21, 2020 Written by Geraint Hughes As a good starting point, I would suggest Sambucol. Many studies have been conducted on it and found it to be beneficial against many different types of flu viruses, none have been conducted on Coronavirus of course, but seeing as Coronavirus is a flu type virus, it seems perfectly reasonable that a cheap, easily available product which assists against one type may also be of benefit against another type. What is Sambucol? If the link is to believed, and I have no valid reason to doubt it, it helps against the flu. Let’s look at some specific research as well. “Elderberry compounds could help minimize flu symptoms, study suggests” This is what they concluded. “What our study has shown is that the common elderberry has a potent direct antiviral effect against the flu virus,” said Dr Golnoosh Torabian.

Structure - Structural Basis of the PNRC2-Mediated Link between mRNA Surveillance and Decapping To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. Figure 1 Comparison of Dcp1aEVH1 with EVH1 Domains from ScDcp1, Mena, Homer, and N-Wasp (A) Schematic diagrams of domain organization of PNRC2 and hDcp1a. (B) Structure of Dcp1aEVH1 (pale green) in complex with PNRC2 (pink) with secondary elements labeled and the N-terminal helix colored in blue. (C) Structure of ScDcp1 (pale green) with the N-terminal region and the insertion helices shown in blue and orange, respectively. (D) Structure of Mena EVH1 domain (lemon) in complex with the FPPPP peptide from ActA (magenta). (E) Structure of the Homer EVH1 domain (lemon) in complex with TPPSPF peptide from mGluR (magenta). (F) NMR structure of N-Wasp EVH1 (lemon) in complex with WIP peptide (magenta). Figure 2 Surface Views of the Interfaces between the EVH1 Domains and Their PRS Ligands Residues involved in the interfaces are labeled and shown as stick models.

An Experiment to Teach Sparrows New Songs Proved a Wild Success You can’t teach an adult bird a new tune. Or can you? New research proves that wild Savannah Sparrows can learn to sing different melodies at two ages, shedding light on critical learning periods for songbirds. Previously only seen in laboratory settings, this is the first experimental study to show the behavior in wild subjects. Savannah Sparrows, which are found in grasslands and coastal habitats across North America, sing slightly varied tunes depending on their location. Mennill’s team took songs recorded on the West Coast and broadcast them to Kent Island birds on the East Coast. Three male Savannah Sparrows singing the typical Kent Island song: Three male Savannah Sparrows singing West Coast songs: Vocal learning occurs when animals echo fresh sounds or modify existing ones based on what they hear in their environment. Trying a new tune didn't seem to affect these sparrows' chances at romance, however. Using the right sound system proved to be a key element.

Des élus parisiens interpellent le préfet de police sur des tirs de gaz lacrymogènes aux abords de deux écoles Une semaine après les affrontements qui ont opposé, mardi 28 janvier après-midi, CRS et pompiers dans le jardin parisien Debergue-Rendez-vous, dans le 12e arrondissement, la colère des parents d’élèves des écoles maternelle et primaire de la rue Marsoulan qui longent le jardin, n’est toujours pas retombée. Au contraire, elle a pris une autre dimension, plusieurs élus de la Ville de Paris interpellant la préfecture de police à ce sujet. « Nous sollicitons votre attention et votre réaction face au traumatisme vécu par les enfants et familles » des deux écoles, « ces faits nécessitent des explications de votre part » écrivent ainsi Patrick Bloche, adjoint à la maire de Paris chargé de l’éducation, Colombe Brossel, adjointe chargée de la sécurité, et Catherine Baratti-Elbaz, maire du 12e arrondissement dans un courrier envoyé lundi 3 février au préfet de police, Didier Lallement. « Il aurait fallu se soucier de la sécurité des enfants en priorité ! » Charge de CRS contre charge de POMPIERS !

Construire un système nerveux fonctionnel | INSB Malgré une composition cellulaire simple (neurones et cellule gliales), la morphologie et la fonction de ces cellules composant le SNC sont extrêmement complexes et variées. Afin d’établir des interactions fonctionnelles, ces deux types cellulaires coopèrent au cours du développement. Du fait de la complexité du SNC et du manque d’outils biologiques, les mécanismes contrôlant cette coopération sont peu étudiés. Les chercheurs de l’Institut de Génomique Fonctionnelle de Lyon en collaboration avec le laboratoire de Richard Mann à l’université Columbia de New York ont utilisé un modèle biologique puissant, la drosophile, qui permet d’étudier la complexité du SNC grâce à des outils génétiques de pointe comme par exemple la technique MARCM qui permet de visualiser des cellules issues d’un même lignage ou la technique Flybow qui permet de visualiser des cellules uniques. Les bases moléculaires de cette plasticité gliale sont inconnues. En savoir plus

Remaining calm in adversity: What Stoicism can teach us during the coronavirus pandemic People around the world are feeling rudderless and adrift. There’s conflicting information about the pandemic – but it’s not just about health. People losing work, feeling frightened, being isolated at home, worried about their loved ones and wondering about getting basic supplies. We all must make ethical decisions in this pandemic. Should I take that second pack of toilet paper for my family, or leave it for the next? Should essential workers stay home to protect themselves? Responses are varied. The more we read, the more anxious we become. Stoicism is an ancient tool for remaining calm in adversity. Stoicism is a school of Hellenistic philosophy that was founded by Zeno of Citium, in Athens, in the early 3rd century BC. Stoics welcomed hard times – they saw their life as training for moments such as the one we are in now, where character, resilience and courage are tested. Keeping calm In times like this it’s easy to spiral into anxiety. Ethics We are all connected Negative visualisation

A Role for H2B Ubiquitylation in DNA Replication To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. Figure 1 H2Bub1 Is Maintained on Replicating DNA ChIP analysis of H2Bub1 and Flag-Bre1 at selected replication origins in log phase cells. (A) H2Bub1 (left) and Flag-Bre1 (right) levels in G2/M and G1 arrested cells. (B–E) G1 cells arrested with α factor were released into 0.2 M hydroxyurea (HU). Error bars indicate the standard deviation from two to three independent experiments (A, C, D, and E) or three technical replicates (B). Figure 2 htb-K123R Cells Are Sensitive to Hydroxyurea and Show a Delay in S Phase Entry (A) Wild-type (WT) and htb-K123R cells were serially diluted and spotted onto YPD plates containing HU and were photographed after 3 days. (B) Rad53 phosphorylation was analyzed by western blot analysis of TCA extracts with a polyclonal Rad53 antibody. See also Figures S2 and S3 . Figure 3 Figure 4 Figure 5 Figure 6 See also Figures S8 and S9 . Figure 7

Rhesus Monkeys Can Assess The Visual Perspective Of Others When Competing For Food -- ScienceDaily Researchers Jonathan Flombaum and Dr. Laurie Santos, both from Yale University, have found that rhesus monkeys consider whether a competitor can or cannot see them when trying to steal food. Working with semi-free-ranging rhesus monkeys on the island of Cayo Santiago in Puerto Rico, Flombaum and Santos set up a food competition game: Lone monkeys were approached by two human "competitors." Each competitor had a grape affixed to a platform by his feet. In each experiment, one of the competitors could see the monkey in front of them, but the other could not. For example, in Experiment 1, one of the competitors stood with his back to the monkey subject, while the other stood facing the subject. In previous studies, rhesus monkeys (and other primates) were thought to do no more than merely follow the gaze of others. Jonathan I. The other members of the research team include Jonathan I.