Trying to Fool Cancer. Photo CLEVELAND — WHEN it airs on Monday, the Ken Burns-produced documentary “Cancer: The Emperor of All Maladies” will emphasize how much more we now know about the genetic basis for .
This year, according to President Obama, cancer research and funding will focus on so-called precision, personalized or targeted medicine — using cancer’s molecular underpinnings to develop drugs that attack the genes or gene products that make up cancer’s factory while sparing normal cells. What a beautiful concept. The problem is, cancer is rarely that simple, or that easily fooled. Three recent studies, all published or presented late last year, highlight the challenges of building a national cancer therapy policy around precision medicine. The first, from me and my colleagues at the Cleveland Clinic in collaboration with Japanese researchers, performed genetic analyses on more than 600 patients with one of two related bone marrow cancers: myelodysplastic syndromes or acute myeloid leukemia.
From Gene to Protein. DNAHistoneModelFinal. 4_Royal Family. Protein shakes, diet killed Perth mum: Meegan Hefford's family calling for tighter restrictions. A FIT and healthy Mandurah mother’s use of protein supplements has been blamed for contributing to her sudden death at the age of just 25.
Meegan Hefford was taking protein shakes and eating protein-rich foods, such as lean meat and egg whites, to get in shape for a bodybuilding competition. Unknown to the mother-of-two, she had a rare genetic disorder that stopped her body from properly breaking down the protein. Urea cycle disorder, which affects one in 8000 people, caused a build-up of ammonia in her blood and accumulation of fluid in her brain. Her family is calling for tighter restrictions on the dietary supplements industry and for warnings about high- protein diets. Ms Hefford, who leaves behind a seven-year-old daughter and five-year-old son, was found unconscious in her Mandurah apartment on June 19. She was rushed to Fiona Stanley Hospital, where doctors scrambled to work out why a young and very fit woman was rapidly losing brain activity. Case Study: Why Are There No Male Calico Cats?
This presentation case study asks two important questions regarding cat coloration: Why are there no male calico cats?
Why is it that clones of calico cats do not look like the original? The case is presented as a slide presentation where students consider evidence and data related to cat coloration and chromosomes. Working in small groups, they discuss the case and eventually answer the two main questions. I usually collect their answers at the end of class to keep students on task. The activity explores concepts that might not be directly included in typical chapters on meiosis, such as Barr bodies and cloning, though I find students really enjoy talking about cats and looking at cat pictures.
New Nice. Genetic_Testing_Lesson6_NWABR. Concord Consortium. Research Overview Geniverse research is being led by our research partner, BSCS, with assistance from our evaluator partner, TERC.
Our research study is examining how the Geniverse materials affect students’ genetics content knowledge and abilities to engage in scientific argumentation. In addition to pre- and post-tests for content knowledge, we will measure both student motivation and the degree of fidelity of implementation of Geniverse. Student demographic variables (race/ethnicity and gender) are being collected to examine if the Geniverse materials provide equitable opportunities for students to learn.
We are also examining the affects of a range of teacher characteristics (years using Geniverse, familiarity with instructional technologies, genetics background and experience with scientific argumentation pedagogies) on student outcomes. The research study began in the fall of 2012 with 48 teachers. Student Outcome Measures.
Origin of a Gene Mutation Causing Early-Onset Alzheimer’s Disease. Geniverse. The Blood Typing Game - about blood groups, blood typing and blood transfusions. What happens if you get a blood transfusion with the wrong blood type?
Even though a patient's own blood type is the first choice for blood transfusions, it's not always available at the blood bank. Try to save some patients' lives and learn about human blood types! Play the Blood Typing Game About this game Embed the Blood Typing Game onto your own web site or blog Swedish version of the game 2012 Winner of the Best Game Category by Swedish Learning Awards. Family Secrets - Lessons - Resources - Life Sciences Learning Center - University of Rochester Medical Center. Hemophilia. BioLogica, Web Labs. Web Lab Directory. Bioinformatics Activity Bank.
The Blood Typing Game. Drag-and-Drop Pedigree: Overview. Bf10231.pdf. How to Grow (and kill) Our Germs: Preschool Science Experiment. Dragon Delivery. Lesson Snapshot.
Double Blasted. In early August of 1945, Tsutomu Yamaguchi had a run of the worst luck imaginable.
A double blast of radiation left his future, and the future of his descendants, in doubt. In this short: an utterly amazing survival story that spans ... well, 4 billion years when you get down to it. Blood Types Tutorial. Bikini Bottom Genetics - Incomplete Dominance. Dragon genetics lab. 23 - Artificial Blood Typing. Gen spbobincdom. Gen spbobdihybird. Blackett Family Pedigree. Create a Blackett Family Pedigree Blackett Family Members The Blackett Family DNA Activity is largely a genetic study of the inheritance of alleles in an extended family.
Bob Blackett has tested DNA samples from himself and 13 other relatives. The first task of a human geneticist is the creation of a family tree, or pedigree to help with the interpretation of genotypes. From the following relationships, construct a pedigree for the Bob and his relatives. Would you like to check your answer? We have prepared a sample pedigree chart of the Blackett family that you can use to check your answer, or to skip this activity if time is limiting. View the Pedigree in a new web page Download the pdf version. Genetic Variation. NIH Curriculum Supplement Series for High School - Human Genetic Variation. BIO_Lone Parent_web.indb - BIO_Lone Parent.pdf.
BIO_Amazing Sperm Race.pdf. CER MitosisMeiosis Final Draft.
Sickle Cell DNA. Cell, Socks, and Sex. Cell, Socks, and Sex Description: This is a fun, easy way to teach the process of mitosis and meiosis.
This will strengthen vocabulary concepts like homologus pairs, diploid, haploid, tetrad and many others. Children Resemble Their Parents. Since the beginning of human history, people have wondered how traits are inherited from one generation to the next.
Although children often look more like one parent than the other, most offspring seem to be a blend of the characteristics of both parents. Centuries of breeding of domestic plants and animals had shown that useful traits — speed in horses, strength in oxen, and larger fruits in crops — can be accentuated by controlled mating. However, there was no scientific way to predict the outcome of a cross between two particular parents. It wasn't until 1865 that an Augustinian Monk named Gregor Mendel found that individual traits are determined by discrete "factors," later known as genes, which are inherited from the parents. Genetics, Biotech, and Decision-Making. Biology Molecular Genetics. HS-LS1-1 Students who demonstrate understanding can: Construct an explanation based on evidence for how the structure of DNA determines the structure of proteins, which carry out the essential functions of life through systems of specialized cells.
HS-LS3-1 Students who demonstrate understanding can: Ask questions to clarify relationships about the role of DNA and chromosomes in coding the instructions for characteristic traits passed from parents to offspring. HS-LS4-1 Students who demonstrate understanding can: Analyze and evaluate how evidence such as similarities in DNA sequences, anatomical structures, and order of appearance of structures during embryological development contribute to the scientific explanation of biological diversity. Molecules called DNA are the instructions that all living organisms use to create all of the characteristics and traits it possesses.
Introduction to the OKSci Framework Return to Biology Introduction. Biology Heredity. HS-LS3-2 Students who demonstrate understanding can: Make and defend a claim based on evidence that inheritable genetic variations may result from: (1) new genetic combinations through meiosis, (2) viable errors occurring during replication, and/or (3) mutations caused by environmental factors. HS-LS3-3 Students who demonstrate understanding can: Apply concepts of statistics and probability to explain the variation and distribution of expressed traits in a population. Characteristics of living things are often passed down from parents to offspring, but there are variations from offspring to parent leading to multiple sources of variation within populations. Variation in individuals can result from different combinations of the genetic material of parents. This is why most siblings do not look identical to each other or to their parents.
An 11-Year-Old Got Most Of Her Genes From Her Dad, And Almost None From Her Mom. How Does Magnification Work? (Mr. Wizard) She thought she was Irish — until a DNA test opened a 100-year-old mystery - Washington Post. Royal family. Cancer Pedigree p53. Joes Pedigree. Nih genetics. Meiosis Case: SRY not SRY. Are your students fascinated by the idea of hermaphrodites? Every year when I talk about worms and other organisms that have both sperm and eggs, I get tons of questions about whether it is possible for humans to have that condition.
Sex and gender determination are complicated topics, and I usually just answer with something brief so that my class doesn’t get too far off topic. However, if you wanted to really get into detail about how sex is determined in humans and why it can be complicated, try this lecture case study: “Meiosis: SRY not SRY” In this case, students are given a scenario based on a true story about a female athlete who was stripped of her medal when it was discovered that her cells contain a Y chromosome. As the case progresses, students learn the basics of how meiosis creates haploid cells that contain a unique set of genes. Download Worksheet (Questions about the Slides, Discussion, and Essay) Link to Google Slides (download to own drive if you want to make changes) Tst1605 26. Products Bioinformatics and the Human Genome Project 1 updated.
Nature. News from Science - Journal. Those Old Kentucky Blues. Teaching Notes Case teaching notes are password-protected and access to them is limited to paid subscribed instructors. To become a paid subscriber, begin the process by registering here. Teaching notes are intended to help teachers select and adopt a case. They typically include a summary of the case, teaching objectives, information about the intended audience, details about how the case may be taught, and a list of references and resources.
Download Teaching Notes Answer Key Answer keys for the cases in our collection are password-protected and access to them is limited to paid subscribed instructors. Get Answer Key. 1170L Artificial Selection. Actualizar el navegador para usar Google Drive - Ayuda de Drive. 1_ProteinEngageFull - Google Slides. Untitled document. Helping you discover more about DNA, genes and genomes, and the implications for our health and society. Genetic Science Learning Center. Launch Tool The Genetic Science Learning Center is a great place to visit to explore and learn about cells, heredity, DNA, genes, natural selection, etc.
The Learn.Genetics part of the site is geared to students, teachers, and the general public. It delivers educational materials on genetics, bioscience, and health topics. The homepage is divided into three main sections: Basics, New & Popular, and a section that highlights a variety of topics, from genetic technology to the new science of addiction. The site uses videos, animations, and interactives to help you explore the different topics. Going Further. Sleep & Gene Expression. Photo Credit: Clipart.com. A Mendel Seminar. Photo Credit: Clipart.com. PEDIGREEQUIZ. ProteinSynthesisSummary. Origami inst. Reading 20DNA. Comments. Dogs Decoded Unit - Mr. Rott's Science Room. Untitled. NIH finally makes good with Henrietta Lacks' family. Over the past six decades, huge medical advances have sprung from the cells of Henrietta Lacks, a poor, African-American mother of five who died in 1951 of cervical cancer.
But Lacks never agreed that the cells from a biopsy before her death taken could be used for research. For years, her own family had no idea that her cells were still alive in petri dishes in scientists' labs. DNA Learning Center. Learn Genetics. Air Pollution Causes Epigenetic Changes That May Trigger Asthma. Once Nadeau understood the role of the methyl groups in gene expression, all the dots began to connect. She believed that air pollution triggered asthma in her Fresno patients by tagging Foxp3 in immature T cells with methyl groups, switching off its expression.
Study of Holocaust survivors finds trauma passed on to children's genes. Genetic changes stemming from the trauma suffered by Holocaust survivors are capable of being passed on to their children, the clearest sign yet that one person’s life experience can affect subsequent generations. They also analysed the genes of their children, who are known to have increased likelihood of stress disorders, and compared the results with Jewish families who were living outside of Europe during the war. “The gene changes in the children could only be attributed to Holocaust exposure in the parents,” said Yehuda. Todd Kenyon TST 2016. Ghost in Your Genes. Geniverse. Genetics Genetic Mutations.
Biology 5E Folder – Google Drive. Explore - Pipe Cleaner Protein Modeling. Biology 5E Protein Folding Teacher Guide. Modified Lesson Plans – Google Drive. DNAHistoneModelFinal. DNA from the Beginning - An animated primer of 75 experiments that made modern genetics. What makes me tick...tock? Circadian rhythms, genetics, and health. Following the introduction of basic principles and key terminology of circadian rhythmicity in Lesson 1, this lesson begins with students discussing model organisms and how scientists use them; Drosophila melanogaster is used as a model for the study of circadian rhythms. Students use several NetLogo simulations to examine how light, temperature, and genetic mutations can affect a fly’s behavior.
Students make connections between these simulations and their own circadian rhythms, developing models throughout the lesson of how three different factors (light, temperature, and genetic mutations) can affect both the flies’ activity levels and their own throughout the day. Great Discoveries in Science: The Double Helix. Hardy Weinberg. Mendelian-genetics-of-corn. Epigenetics II: DNA Methylation in Arabidopsis. Jermel Watking, Bruce Nash, and David Micklos DNA Learning Center, Cold Spring Harbor Laboratory.