background preloader

Autism brain imaging PS1030

Facebook Twitter

Journal of Neurology, Neurosurgery & Psychiatry. S Baron-Cohen Correspondence to: S Baron-Cohen Autism Research Centre, Departments of Experimental Psychology and Psychiatry, University of Cambridge, Douglas House, Cambridge CB2 2AH, UK; sb205@cam.ac.uk.

Journal of Neurology, Neurosurgery & Psychiatry

Cognitive skills in children with autism vary and improve, study finds - UCL Institute of Education, University College London. 15 September 2010 People with autism spectrum disorders (ASD) are thought to have a specific profile of cognitive strengths and weaknesses—difficulties appreciating others' thoughts and feelings, problems regulating and controlling their behavior, and an enhanced ability to perceive details— but few studies have tracked children's cognitive skills over time.

Cognitive skills in children with autism vary and improve, study finds - UCL Institute of Education, University College London

Now new longitudinal research provides clues that can inform our understanding of ASD. Cognition and behavior: Language defect identified in autism — Language comprehension: Low-functioning children with autism differ from those with intellectual disability alone in that they understand less than their verbal ability suggests.

Cognition and behavior: Language defect identified in autism —

Children who have both autism and intellectual disability may understand fewer words than their speaking skills suggest, which is not the case for typically developing children or those with intellectual disability alone. The results were published 21 February in the Journal of Autism and Developmental Disorders1. Language impairment is a core symptom of autism, and may be closely tied with social deficits, another key feature of the disorder.

For example, children whose attention is not focused on their parents and caregivers might not pick up on the cues required for language learning. Cognition in autism: one deficit or many? Ss15205.pdf. DSM-IV-Defined Asperger Syndrome: Cognitive, Behavioral and Early History Differentiation from High-Functioning Autism. Developmental Trajectories in Siblings of Children with Autism: Cognition and Language from 4 Months to 7 Years. Autism: beyond “theory of mind” Other minds in the brain: a functional imaging study of “theory of mind” in story comprehension. A Wellcome Department of Cognitive Neurology, Institute of Neurology, 12 Queen Square, London WC1N 3BG, UKb MRC Cognitive Development Unit, 4 Taviton Street, London WC1H 0BT, UKc Royal Free Hospital Medical School, Roland Hill St, London NW3, UKd Department of Psychology, University College London, Gower St, London WC1E 6BT, UK Received 16 August 1995, Revised 20 October 1995, Available online 5 April 2000 Choose an option to locate/access this article: Check if you have access through your login credentials or your institution Check access.

Other minds in the brain: a functional imaging study of “theory of mind” in story comprehension

Does the autistic child have a “theory of mind” ? Sciencedirect. To view the full text, please login as a subscribed user or purchase a subscription.

sciencedirect

Click here to view the full text on ScienceDirect. Figure 1 Estimated linear trends (on the basis of the mixed regression analysis) across time in the dichotomized scores of the affective speech comprehension as a function of condition (Oxytocin vs. Sciencedirect. To view the full text, please login as a subscribed user or purchase a subscription.

sciencedirect

Click here to view the full text on ScienceDirect. Fig. 1 Region of maximum activity in the region of the anterior paracingulate cortex elicited when subjects adopted an ‘intentional stance’. This image displays group data mapped onto a template brain. Fig. 2 The points of maximum activity in the anterior cingulate cortex found to be associated with autonomic arousal, cognitive demand and response conflict displayed with the same data from theory-of-mind studies in the anterior paracingulate cortex. Fig. The sabotage and deception task. Abstract. Intentional attunement: A neurophysiological perspective on social cognition and its disruption in autism. Volume 1079, Issue 1, 24 March 2006, Pages 15–24 Multiple Perspectives on the Psychological and Neural Bases of Understanding Other People's Behavior Edited By Jennifer Beer, Jason Mitchell and Kevin Ochsner Research Report Vittorio Gallese Dipartimento di Neuroscienze, Università di Parma, Via Volturno 39, 43100 Parma, Italy Accepted 11 January 2006, Available online 28 February 2006 Choose an option to locate/access this article:

Intentional attunement: A neurophysiological perspective on social cognition and its disruption in autism

PsycNET - Display Record. Sciencedirect. To view the full text, please login as a subscribed user or purchase a subscription.

sciencedirect

Click here to view the full text on ScienceDirect. Objective. Empathy and Cognition in High-Functioning Children with Autism - Yirmiya - 2008 - Child Development. Brain imaging research is often wrong. This researcher wants to change that. When neuroscientists stuck a dead salmon in an fMRI machine and watched its brain light up, they knew they had a problem.

Brain imaging research is often wrong. This researcher wants to change that.

It wasn't that there was a dead fish in their expensive imaging machine; they'd put it there on purpose, after all. It was that the medical device seemed to be giving these researchers impossible results. Dead fish should not have active brains. The lit of brain of a dead salmon — a cautionary neuroscience tale. (University of California Santa Barbara research poster) The researchers shared their findings in 2009 as a cautionary tale: If you don't run the proper statistical tests on your neuroscience data, you can come up with any number of implausible conclusions — even emotional reactions from a dead fish. In the 1990s, neuroscientists started using the massive, round fMRI (or functional magnetic resonance imaging) machines to peer into their subjects' brains. When other scientists try to reproduce the results of original studies, they too often fail.

Neuroimaging. Para-sagittal MRI of the head in a patient with benign familial macrocephaly.

Neuroimaging

Neuroimaging includes the use of various techniques to either directly or indirectly image the structure, function/pharmacology of the nervous system. It is a relatively new discipline within medicine and neuroscience/psychology.[1] Physicians who specialize in the performance and interpretation of neuroimaging in the clinical setting are neuroradiologists. Functional imaging. Functional imaging is the study of human brain function based on analysis of data acquired using brain imaging modalities such as Electroencephalography (EEG), Magnetoencephalography (MEG), functional Magnetic Resonance Imaging (fMRI), Positron Emission Tomography (PET) or Optical Imaging. The aim is to understand how the brain works, in terms of its physiology, functional architecture and dynamics. The framework for the conduct of these studies includes classical techniques of neuroanatomy, neurophysiology, and experimental psychology and the cognitive neurosciences, as well as more theoretical approaches, based on perspectives from computational neuroscience and statistics.

Modern functional imaging has two main advantages over the multi/single-unit recordings used to study the electrophysiology of neurons. The first is that it is generally non-invasive, and is therefore applicable routinely in humans. MRI? fMRI? PET scans? MRI is a technology for imaging sections of the body that uses an interesting physical property of matter in response to powerful magnetic fields. The magnetic field is manipulated and the tissues of the body actually give off radio waves in response. The rest of the process is basically a very complicated radio directional finder that figures out exactly how much radio signal is coming from which spot in the body.

The computer then draws a series of black and white pictures that look like what would be seen if the human body was sliced like a loaf of bread. SPECT vs MRI, fMRI & PET. Download?rep=rep1&type=pdf&doi=10.1.1.9. Cognitive Neuroimaging Laboratory - Neuroimaging. When analyzing the averaged, stimulus-locked EEG signal, a number of waveforms (‘peaks’) can be identified, and characterized by their polarity, order of occurrence, and origin. Components are labeled by their polarity (Positive or Negative) and relative order/time (1 or 100) such that the first positive deflection of an ERP curve is commonly labeled P1, or P100, and they are divided into exogenous or endogenous categories.

The exogenous, or early, components of the ERP curve are more a reflection of the initial neural processing of the physical characteristics of a stimulus. These responses are automatic responses to the stimulus and, hence, the magnitudes of these exogenous components are not very dependent on the cognitive processing of the stimulus. CBF changes during brain activation: fMRI vs. PET. EEG vs MRI, fMRI and PET -Epilepsy Awareness Program - Middle East Medical Information Center and Directory. Electroencephalography (EEG) is a non-invasive test for epilepsy during which several electrodes are placed on a patient's scalp to record electrical impulses from the brain (brain waves).

It is sometimes called a brain wave test, used for testing patients with epilepsy, a brain tumor, a brain abscess, brain trauma, subdural hematoma, meningitis, encephalitis, stroke or congenital defects of the brain. It is performed by using a device that measures the fluctuations and patterns in electrical processes within the brain. More information on EEG MRI is a magnetic resonance imaging: the use of nuclear magnetic resonance of protons to produce proton density images. PET Scans and fMRI Compared. The positron emission tomography (PET) scan measures blood flow in the brain.

This is accomplished by injecting a person or animal with a radioactive isotope (i.e. an unstable atom, usually a variation of oxygen that has a short-half life); this isotope will quickly decay. Founded on the assumption that blood flow will increase in areas of the brain that are in heavy use (such as when a person is viewing an object or reading words or some other cognitive-intensive function), a fair portion of the injected isotopes will end up in the active part of the brain. As the isotopes decay, a positron (a small particle with the exact opposite charge as an electron) is released.

This positron will collide with an electron and they will annihilate each other, sending two gamma ray particles in exactly opposite directions. Neuroimaging of autism. Neuroimaging and Autism. Home DNA Learning Center Preparing students and families to thrive in the gene age Website Search. What Neuroimaging has Taught us about the Brain in Autism Spectrum Disorder: a Selected Review — NDCN. 10. Npy.12. Quinton Deeley Neuroimaging in disorders of social cognition. Review of neuroimaging in autism spectrum disorders: what have we learned and where we go from here. Untitled.

Over the past decade, human neuroimaging studies have provided invaluable insights into the neural substrates that underlie autism spectrum disorder (ASD). Although observations from multiple neuroimaging approaches converge in suggesting that changes in brain structure, functioning and connectivity are associated with ASD, the neurobiology of this disorder is complex, and considerable aetiological and phenotypic heterogeneity exists among individuals on the autism spectrum. Characterization of the neurobiological alterations that underlie ASD and development of novel pharmacotherapies for ASD, therefore, requires multidisciplinary collaboration.

Consequently, pressure is growing to combine neuroimaging data with information provided by other disciplines to translate research findings into clinically useful biomarkers. Autistic-spectrum disorders: lessons from neuroimaging. Brain Scans Show Differences in Adults With Autism. By Maureen Salamon. Autism – Say NO to MRI and PET Scans for Diagnosis. Majid Ali, M.D. Brain Scans Show Differences in Adults With Autism. Please note: This article was published more than one year ago. The facts and conclusions presented may have since changed and may no longer be accurate. And "More information" links may no longer work. Questions about personal health should always be referred to a physician or other health care professional. By Maureen SalamonHealthDay Reporter. Brain Trauma, PET Scans and Forensic Complexity - PsychSource. Controlling attention to gaze and arrows in childhood: an fMRI study of typical development and Autism Spectrum Disorders - PsychSource.

Functional brain imaging of childhood clinical disorders with PET and SPECT - PsychSource. Young children with autism show atypical brain responses to fearful versus neutral facial expressions of emotion - PsychSource. Brain imaging: Applications in psychiatry - PsychSource. What kind of a person volunteers for a free brain scan? Problems with brain imaging papers. Brain imaging and individual talents.

PET

fMRI. Sciencedirect. Appi.ajp.157.12. Autism can be diagnosed with brain scan – study.