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The End of Theory: The Data Deluge Makes the Scientific Method Obsolete

The End of Theory: The Data Deluge Makes the Scientific Method Obsolete
But faced with massive data, this approach to science — hypothesize, model, test — is becoming obsolete. Consider physics: Newtonian models were crude approximations of the truth (wrong at the atomic level, but still useful). A hundred years ago, statistically based quantum mechanics offered a better picture — but quantum mechanics is yet another model, and as such it, too, is flawed, no doubt a caricature of a more complex underlying reality. The reason physics has drifted into theoretical speculation about n-dimensional grand unified models over the past few decades (the "beautiful story" phase of a discipline starved of data) is that we don't know how to run the experiments that would falsify the hypotheses — the energies are too high, the accelerators too expensive, and so on. Now biology is heading in the same direction. In short, the more we learn about biology, the further we find ourselves from a model that can explain it. There is now a better way.

https://www.wired.com/2008/06/pb-theory/

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