Collège de France

Paris's top 10 hidden shopping passages At the end of the 18th century, town planners in Paris created a labyrinth of hidden passages across Paris. Over the years many fell into disrepair or were demolished, but if you know where to look you can still push back a doorway and walk into a fabulous belle époque arcade, a glittering art nouveau galerie or an ancient courtyard. Here are 10 worth tracking down. Passage du Grand Cerf The Grand Cerf was restored to its former glory a few years ago and could be the most beautiful Parisian passage. The Digital Public Library of America: adding gravitas to your Internet search One year ago, a group of professors, librarians, and futurists gathered in San Francisco to discuss how they would go about building a Digital Public Library of America. There were still many questions about the project, which had millions of dollars in charitable funding but hadn’t yet meted out a complete vision of its incarnation. The directors cited Europeana and Wikipedia as examples, but they weren’t sure how a digital library would tackle the problems unique to using published content in America. Despite the hurdles ahead, the founders of the DPLA promised at that conference that a live website would launch in April 2013, come hell or high water. The founders of the DPLA made good on their promise this week.

101! Clock Face Font Download Home » Decorative » 101! Clock Face » 101! Clock Face Your download will start in 20 seconds... If not, try the following links Information Voltage-dependent calcium channel signaling mediates GABAA receptor-induced migratory activation of dendritic cells infected by Toxoplasma gondii Abstract The obligate intracellular parasite Toxoplasma gondii exploits cells of the immune system to disseminate. Upon T. gondii-infection, γ–aminobutyric acid (GABA)/GABAA receptor signaling triggers a hypermigratory phenotype in dendritic cells (DCs) by unknown signal transduction pathways. Here, we demonstrate that calcium (Ca2+) signaling in DCs is indispensable for T. gondii-induced DC hypermotility and transmigration in vitro. We report that activation of GABAA receptors by GABA induces transient Ca2+ entry in DCs.

Eight sounds that tell you you're in Paris There are a few sounds that everyone associates with Paris: impatient drivers beeping their horns at traffic lights, sirens on speeding police cars and the sound of scooters cruising past cafés. Then there's the bell ringing cyclists, the din from the packed bars and terraces and the sounds of tour guides on buses or boats. But it's rare for people to take the time to appreciate the hidden aural gems just waiting to be discovered, the city's resident sound expert and author of the Soundlandscapes' blog, Des Coulam, told The Local. "We live in a very visual world," Coulam said. "But Paris is a very sound rich city if you take time to explore it in this way."

160 Free Textbooks: A Meta Collection Free textbooks (aka open textbooks) written by knowledgable scholars are a relatively new phenomenon. Below, find a meta list of 200 Free Textbooks, and check back often for new additions. Also see our online collection, 1,700 Free Online Courses from Top Universities. Electronic Brick : BUS Most of the sensor and switch are a single line for signal. There is some other module need more than one signal line, so we need the bus connection. The 1602LCD module have 16 pins, there are 5 power pins and 11 signal pins. To control the 1602LCD module at least 10 pins, so we need a bus to connect it to Arduino. Connect the 1602LCD Brick with the 10pins cable to the BUS2 connector of Chassis.

The structure of the COPI coat determined within the cell We collected a dataset of 29 cryo-electron tomograms, each containing a clearly-visible Golgi stack. Most Golgi stacks in our dataset consisted of nine cisternae that exhibited reproducible morphology (Figure 1A–B, Video 1). Luminal density progressively darkened through the cis and medial Golgi, while the cisterna centers narrowed and edges swelled. The final trans cisterna and the adjacent ballooning compartments of the trans-Golgi-network (TGN) both contained a translucent lumen (Figure 1A). All three archetypal protein coats could be visually identified in the tomograms without any ambiguity: clathrin-coated vesicles were found in the vicinity of the TGN and were distinguished by their characteristic triskelion-based cage (Figure 1C,C’), while ER exit sites with COPII buds and vesicles were distinguished by their two-layered coat (Figure 1D,D’).