GPUGRID. Poem@HOME. POEM@HOME. POEM@Home. Logo of POEM@Home POEM@Home is a distributed computing project hosted by the Karlsruhe Institute of Technology and running on the Berkeley Open Infrastructure for Network Computing (BOINC) software platform. It models protein folding using Anfinsen's dogma. POEM@Home was started in 2007.[1] The POEM@home applications are proprietary. Scientific objectives[edit] The project intends to study how protein structure determines protein function, predict a protein's structure from its amino acid sequence, investigate how proteins interact with each other, and understand how malfunctioning proteins can cause functional disorders. See also[edit] List of distributed computing projects References[edit] External links[edit]
Similarity Matrix of Proteins (SIMAP) SIMAP. SIMAP - Similarity Matrix of Proteins. Rosetta@home. Fluorescent proteins designed from scratch Congrats to all Rosetta@home volunteers who contributed to a recent report in Nature describing the design of a completely artificial fluorescent beta-barrel protein. As described by one of the main authors, Anastassia, in this forum post: The paper presents many “firsts” in computational protein design. It is the first de novo design of the beta-barrel fold (one of the most described folds in the past 35 years, yet mysterious until now). It is also the first de novo design of a protein tailored to bind a small-molecule, which requires very high accuracy in the placement of side chains on protein backbones assembled from scratch.
Thanks to all the Rosetta@home volunteers who contributed to the validation of our designed proteins and binding sites. Here is the link to the IPD webpage that contains a copy of the paper. Rosetta Android version 4.10 released ... more. Welcome to Foldit!!