Synthetic Biology

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WHAK!

http://www.edge.org/3rd_culture/kelly07/kelly07_index.html [KEVIN KELLY:] The main question that I'm asking myself is, what is the meaning of technology in our lives? What place does technology have in the universe? What place does it have in the human condition?
Tim Brown, CEO of IDEO selects Wendell Lim, synthetic biologist Wendell runs a lab at the University of California, San Francisco, focusing on synthetic biology... http://www.syntheticaesthetics.org/

Synthetic Aesthetics

http://arstechnica.com/science/news/2010/08/systems-and-synthetic-biology-neither-models-nor-miracles.ars The 20th century broke open both the atom and the human genome. Physics deftly imposed mathematical order on the upwelling of particles. Now, in the 21 st century, systems biology aims to fit equations to living matter, creating mathematical models that promise new insight into disease and cures. But, after a decade of effort and growth in computing power, models of cells and organs remain crude. Researchers are retreating from complexity towards simpler systems.

Neither models nor miracles: a look at synthetic biology

Very nice approach indeed: "Synthetic biology does away with systems biology's untidiness by focusing on individual parts, creating a tool set for engineering organisms unconstrained by biology as we know it, making the discipline more like software programming." by nicolas Aug 26

News

By John Timmer, Ars Technica Biological systems have caught the attention of computer scientists, who have been turning everything from RNA molecules to entire bacterial colonies into logic gates. So far, however, these systems have been relatively small-scale, with only a handful of gates linked up in a series. Today’s issue of Science leapfrogs past the small-scale demonstrations, and shows that a form of DNA computing can perform a calculation with up to 130 different types of DNA molecules involved. http://www.wired.com/wiredscience/tag/synthetic-biology/

Main Page - ung.igem.org

Register Now! Regular registration has ended, but late registration is now open! The deadline is May 1st. See details and register for your division below. http://ung.igem.org/Main_Page
In our previous article, The 15 Coolest Cases of Biomimicry , we listed such great ideas as Velcro, Gecko Tape and Whalepower Wind Turbines to illustrate some of the most awe-inspiring applications of biomimicry: the developing engineering practice of designing sustainable human technologies inspired by nature. Here are 15 more examples coming out of the biomimetics workshops of academia and industry that illustrate the range of nature-inspired designs that may lead humanity into the future. On the energy front biomimicry is offering several intriguing designs for tapping the movement of waves and tides to produce electricity from mechanical energy. An Australian company BioPower Systems has developed Biowave , a system that mimics the motion of underwater plants to generate power. Buoyant blades are anchored to the seabed and can bend and rotate in the currents to generate electricity. http://brainz.org/15-incredible-applications-biomimicry/

Current Interest - 15 Incredible Applications of Biomimicry

Current Interest - The 15 Coolest Cases of Biomimicry

Those who are inspired by a model other than Nature, a mistress above all masters, are laboring in vain. - Leonardo Da Vinci Biomimicry - The practice of developing sustainable human technologies inspired by nature. Sometimes called Biomimetics or Bionics, it's basically biologically inspired engineering. 1. http://brainz.org/15-coolest-cases-biomimicry/

Congress Considers Synthetic Biology Risks, Benefits - ScienceIn

http://news.sciencemag.org/scienceinsider/2010/05/congress-considers-synthetic-bio.html?etoc A week after J. Craig Venter announced success in synthesizing a genome and using it to control a self-replicating cell, he was at the microphone again, this time testifying in front of the U.S. House Committee on Energy and Commerce. Along with two other synthetic biology experts, a bioethicist, and Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, Venter navigated a generally supportive round of questions concerning the potential benefits and risks of synthetic biology.
The final evaluation report of the BBSRC/EPSRC Synthetic Biology Dialogue has now been published. The report examines the outcomes of the dialogue 6 months after it was completed. It includes interviews with participants and stakeholders as well as mapping of activity on Twitter, citations and links to the report in speeches, at meetings and online. http://www.bbsrc.ac.uk/news/policy/2011/110418-n-synthetic-biology-dialogue-final-report.aspx

18 April 2011 - Final evaluation report of the BBSRC/EPSRC Synthetic Biology Dialogue is published - News - BBSRC

http://www.mirasoldisplays.com/benefits/technology

Current Interest - How mirasol Displays Work: Micro-electro-mechanical Systems (MEMS) Drive IMOD Reflective Technology | mirasol® Displays

Overview of mirasol Display Benefits Qualcomm’s mirasol displays are a technology breakthrough that deliver substantial performance benefits over competing display technologies. Never before has a single display technology supported color and interactive content while also offering crisp visibility inside and outdoors with energy efficiency to provide weeks of battery life. Crisp Content Even in Bright Sunlight

Systems & Synthetic Biology

What physics was to the 20th century, biology will be to the 21st, and Quantitative Biology (Systems Biology and Synthetic Biology) will be a vital part of it. Systems Biology is a merger of Systems and Control Theory with Molecular and Cell Biology . Systems biology aims to explain how higher level properties of complex biological systems arise from the interactions among their parts. This new field requires a fusion of concepts from many disciplines, including biology, computer science, applied mathematics, physics and engineering. Systems Biology is about " quantitative, predictive and dynamical biology ". The ultimate aim of "quantitative, predictive and dynamical biology" is a reliable computational model of the cell, and a " Integrative Systems Physiology " model of the organism.
Analyzing the history of a technology requires a complex look at the social, economic, and political context in which it emerged, and the reciprocal influences that the developing technology exerts on these factors. Predicting what the future of a technology will be like, how it will affect the economy and understanding the potential risks and payoffs is much much harder. Rob Carlson's new book , Biology is Technology: The Promise, Peril, and New Business of Engineering Life takes on this challenge, looking at the recent history and potential future of synthetic biology and biological engineering from the perspective of a biotech entrepreneur, discussing the science, the economics, and the politics of this emerging technology. Through a series of case studies, the book highlights many of the difficult contradictions inherent in the development of biological technologies.

Biology is Technology : Oscillator

Following up on my post of several weeks ago ( iGEM 2011: First Thoughts ), here is a bit more on last year's Jamboree. I remain very, very impressed by what the teams did this year. And I think that watching iGEM from here on out will provide a sneak peak of the future of biological technologies. I think the biggest change from last year is the choice of applications, which I will describe below.

synthesis

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Institute News

DIYbio/FAQ - OpenWetWare

"biopunk" , "sciencemadness", "biohacker", j'adore cette philosophie: la biologie de garage. On est en plein SF ! :) by nicolas Aug 17

Edge Master Class 2009

learn synthetic biology from the best possible teachers ! by dbikard Sep 1

Tools

GeneDesign is a web-based program for the design of synthetic genes. It consists of several modules that automate the tasks associated with the manipulation of synthetic sequences.

There are many ways to use GeneDesign. Probably the most common is to start with the protein sequence of an interesting gene and proceed through reverse translation to building block design. This path is explored in the Design a Gene section of the manual. by dbikard Apr 14

Mobyle portal

A very nive global portal with multiple tools from mFold to multiple alignments etc. by dbikard Apr 14

http://www.evolva.com/