In Africa, Scientists Are Preparing to Use Gene Drives to End Malaria - MIT Technology Review. In Burkina Faso, Mali, and Uganda, the groundwork is being laid for a powerful kind of experiment.
A project now under way aims to release mosquitoes that have been genetically programmed to drive themselves and their malaria-causing brethren toward extinction. As we wrote last year, the program, called Target Malaria, is meant to use a gene drive to drastically reduce the number of mosquitoes that transmit the disease in sub-Saharan Africa, where it kills hundreds of thousands of people a year. Not long ago this was merely theoretical, but modified mosquitoes with gene drives on board are already being bred and tested in labs. The idea is that a so-called selfish gene with effects that would ultimately doom the population is introduced and then replicates itself at a far higher rate than normal, spreading rapidly.
Target Malaria, which is funded by the Bill and Melinda Gates Foundation, is exploring several ways to use this technology. It's time to confront Africa’s invisible killer. Africa Telemedicine Outlook and Opportunities Report 2017: e-health Scenario and Future Government Plans for Development of e-Health Space - Research and Markets. DUBLIN, Mar 02, 2017 /PRNewswire/ -- Research and Markets has announced the addition of the "Africa Telemedicine Outlook and Opportunities" report to their offering.
The report titled "Africa Telemedicine Outlook and Opportunities" provides a comprehensive analysis of e-Health scenario in Africa covering market challenges and success case studies by countries and at multinational levels. The report discusses about the current health scenario of different countries such as South Africa, Kenya, Ghana, Nigeria, Uganda, Botswana, Cameroon and Ethiopia. The report also provides current e-health scenario and future government plans for development of e-Health space in all countries. The report also includes trends & developments, growth drivers and major restraints, and challenges within the industry to understand current market dynamics in the industry. Key Topics Covered: 1. New program aims to build genetics research capacity in Africa. February 24, 2017—A new collaboration between researchers at Harvard T.H.
Chan School of Public Health, the Stanley Center for Psychiatric Research at the Broad Institute of MIT and Harvard, and six African universities and institutes aims to boost genetics research capacity in Africa, and ultimately to help close gaps in knowledge about mental health in a population historically excluded from genetics research.
The GINGER (Global Initiative for Neuropsychiatric Genetics Education in Research) program has recruited 17 young African scientists who, over the course of two years starting this July, will attend workshops in Boston and London on topics including epidemiology, bioinformatics, genetics, and grant writing. In between, they will return to their home universities, where they’ll receive virtual mentoring and onsite research skills training. The trainees will ultimately become trainers themselves, and share what they’ve learned with their colleagues. —Amy Roeder. Africa Telemedicine Outlook and Opportunities Report 2017: e-health Scenario and Future Government Plans for Development of e-Health Space - Research and Markets.
Pan-African public health body launched to avert crises. The Africa Centers for Disease Control and Prevention (Africa CDC) was officially launched last week at a summit of the African Union, whose membership includes every nation on the continent.
African leaders formally endorsed the idea of an African CDC last year. With the memory of the 2014-16 Ebola crisis – which quickly proliferated and left more than 11,000 people dead – still fresh, they urged for its establishment to be fast tracked. Backed by a portion of the AU’s budget contributed by its members, the Africa CDC will work to prevent another crisis like Ebola, for which African nations and the world were sorely underprepared. It will support AU member states in preventing, detecting and responding to public health threats by improving areas such as monitoring, early warning systems and response capacity. After making substantial gains on immunisation, in recent years the continent’s progress has stalled and it is falling behind on meeting global immunisation targets. First drug-resistant malaria parasite detected in Africa. MIAMI – For the first time in Africa, a malaria parasite has been found to be partially resistant to the top anti-malaria drug, artemisinin, researchers said Wednesday, raising concern about efforts to fight a disease that sickens hundreds of millions of people each year.
The discovery means that Africa now joins Southeast Asia in hosting such drug-resistant forms of the mosquito-borne disease. Malaria infected more than 200 million people and killed some 438,000 people worldwide in 2015, most of them children in Africa. “The spread of artemisinin resistance in Africa would be a major setback in the fight against malaria, as ACT (artemisinin-based combination therapy) is the only effective and widely used antimalarial treatment at the moment,” said lead author Arnab Pain, professor at the King Abdullah University of Science and Technology. “Therefore, it is very important to regularly monitor artemisinin resistance worldwide.” The study was published in the New England Journal of Medicine. Diagnosing Africa’s medical brain drain. Dressed in full medical gear and clutching a folder, Folu Songonuga, a physiotherapist, walked briskly across the lobby in the offices of Activa Rehabilitation Services in Orange, New Jersey, United States.
An elderly man, evidently in pain, had just been wheeled into an inner room, and Dr. Songonuga was on his way to tend to the patient. “I see up to 20 patients a day,” Dr. Songonuga, a Nigerian by birth but now a naturalized American, told Africa Renewal. Together with his compatriot Olufemi Dosumu he owns the rehabilitation business, established in 1996, and they plan to expand to other states. New Genetic Chip A Step Toward Diversity In African Genome Sequencing. DNA sequence.
Image: Shutterstock/futureoflife.org Africa is uncharted territory when it comes to sequencing genomes and studying genetic causes for diseases that affect Africans disproportionately, but a new genetic chip is a step forward for medicine on the continent, Quartz reported. The genetic chip project has been an Africa-led effort from the start, said Nicola Mulder, a bio-informatician at the University of Cape Town in South Africa who led the work. However, parts of the project have been conducted in the U.S. and Europe because African countries don’t yet have the equipment to sequence entire human genomes fast, Quartz reported.
Hope for Africans as the Medicines Patent Pool Announces First Licence for Tuberculosis Treatment. The Medicines Patent Pool has announced signing a licence with Johns Hopkins University to facilitate the clinical development of tuberculosis (TB) drug candidate sutezolid.
Long considered a promising investigational treatment, its further development in combination with other drugs, could offer hope to millions of African suffering from TB particularly those that are both drug-sensitive and or with drug-resistant TB. “We are proud to work with Johns Hopkins University to encourage the further development of sutezolid, a potentially important component of new TB regimens,” said Greg Perry, MPP’s Executive Director.
“Faster acting, better therapies to treat TB are a particularly urgent global public health priority. With the exception of two new drugs that have come to market recently, the dearth of new alternatives to decades-old TB drugs contributes to our limited response to the epidemic.” The MPP was founded and remains fully funded by UNITAID. African leaders hailed as countries make gains against malaria. January 30, 2017 Eight countries recognised for efforts to reduce malaria incidence and deaths ADDIS ABABA, ETHIOPIA (30 January 2017) – At a time of historic progress toward a malaria-free Africa, the African Leaders Malaria Alliance (ALMA) honoured eight African countries that have shown commitment and innovation in the fight against the disease.
Today at the 28th African Union Summit, the 2017 ALMA Awards for Excellence were awarded to: • Botswana, Cabo Verde, Comoros, Democratic Republic of Congo (DRC), Ethiopia, Swaziland and Uganda, for their impact on malaria incidence and mortality; and. Study shows anemia may protect children against malaria in Africa. CHAPEL HILL, N.C., Jan. 5 (UPI) -- Researchers at the University of North Carolina have found that anemia may protect against malaria in a new study of African children.
A study by UNC Chapel Hill in collaboration with the Medical Research Unit in The Gambia and the London School of Hygiene & Tropical Medicine, found that iron supplements used to treat anemia may have detrimental effects on children with little access to healthcare in malaria-endemic countries such as those in Africa. Iron deficiency anemia is the most common form of nutritional deficiency in the world and can cause long-term adverse health problems in children. The UNC study shows that iron deficiency anemia may actually protect children against the blood-stage of Plasmodium falciparum malaria and treating anemia with iron supplements removes this protection.
African trees kill both malaria mosquitos and the parasite. Malaria is one of the world's most serious infectious diseases and affects more than 200 million people each year. Scientists at the University of Oslo have examined the bark from two African trees and found substances that can kill both the mosquitoes that transmit malaria, and the parasite itself. Traditional healers in West Africa have for many years used extracts from the bark of two trees in the citrus family (Rutaceae) to treat malaria, which is a widespread disease in the region and kills hundreds of thousands of people worldwide every year.
Researchers at the School of Pharmacy at the University of Oslo in Norway have now shown that bark from the trees contains substances that not only kill the malaria parasite, but also the mosquitoes that transmit the disease. "This project started in 2011, when we were approached by the entomologist Bertin Mikolo fra Marien Ngouabi University(link is external) in the Republic of Congo's capital Brazzaville. Afrique : 113 millions de médicaments contrefaits saisis. 900 millions de saisies en 4 ans. Mortality rates due to Hypertension and Diabetes on the rise in Africa. Africa has highest rate of high blood pressure, WHO says.
Image copyright EPA Africa has the highest rate of high blood pressure in the world, affecting about 46% of adults, a World Health Organization (WHO) study has found. It blamed increasing urbanisation and unhealthy lifestyles for the rise in cases. The global average for the number of people suffering from the condition was about 40%, the WHO said. High blood pressure was often detected too late and was a silent killer, it added. If lifestyles do not change, more people in Africa could die from chronic illnesses, including diabetes and cancer, than infectious disease by 2030, the WHO said. Africa: Zika Virus Incidences Reach 15.6 Per Cent. By Maureen Odunga National Institute for Medical Research (NIMR)'s just released study findings show that 15.6 per cent of the 533 people whose blood samples were tested have Zika virus. Presenting the institute's achievements over the year, NIMR Director General, Dr Mwele Malecela, said in Dar es Salaam the study also discovered that out of 80 toddlers born with physical disabilities, 43.8 per cent were traced with the virus.
NIMR conducted the study in partnership with Bugando Catholic University of Health and Allied Sciences, she said. Africa: More Women in Africa Using Family Planning. By Evelyn Lirri The number of women and girls using modern contraception methods has grown by 5.3 million or 22 per cent in East and Southern Africa since the Family Planning 2020 (FP2020) initiative was launched in 2012. According to a mid-term review report, Family Planning 2020 (FP2020), Ethiopia, Kenya, Mozambique, Uganda and Zambia registered some of the highest numbers of women and girls who are using modern family planning methods. In Kenya, an additional 1.15 million new users have been added since 2012 while Uganda has registered an additional 844,000 new users. Ethiopia registered an additional 1.5 million new users while in Zambia that figure grew by 524,000 women and girls. In countries covered by the FP2020 initiative, up to 30.2 million more women and girls have been accessing modern family planning methods in the past four years, according to the report.
HIV 'game-changer' now on NHS. Image copyright SPL A drug that dramatically reduces the risk of being infected with HIV will now be given to patients by the NHS in England. The Comoros on the verge of completely eradicating malaria. The Comoros is on the verge of eradicating the malaria epidemic across the entire archipelago. Thanks to two successive campaigns launched in 2005 and 2010 on the three islands, the number of malaria cases has dropped from 54,078 in 2004 to 1,052 in 2015, a fall that is well over 98%. And since 2014, the hospital mortality rate due to malaria is dropped to nearly 0%.
Dr Afane, coordinator of the malaria control program in Comoros said: “Our goal is to break the chain of transmission. Now we have been able to break it in Anjouan, there haven’t been any cases since 2014, same as Moheli. African Targets to End AIDS, TB and Malaria by 2030. Johannesburg, November 2016- Strengthening and strategic refocusing of Africa’s partnerships to respond effectively to continental priorities for sustainable development is a critical priority for the African Union. Ensuring that Africa has the right strategies to finance its own development and reducing aid dependency are centerpieces in driving structural transformation. Monthly cost of providing key drugs could be $1-2 per person, experts say - Health.
Health & WASH in sub-Saharan east Africa; Key challenges & health threats - Communicable diseases. Titled. 17 November 2016 – Having secured the funds for the initial phase of the deployment of the world’s first malaria vaccine, the World Health Organization (WHO) announced today it will be rolled out in sub-Saharan Africa and immunization campaigns will begin in 2018.
“The pilot deployment of this first-generation vaccine marks a milestone in the fight against malaria,” stated Dr. 18.2m Africans will be diabetic by 2030 - WHO. By Sola Ogundipe &Gabriel Olawale. Africa: Agreement for Pharmaceutical Development in Africa Inked. Constantine — An agreement for the pharmaceutical development between Algeria and several Maghreb and African countries was signed Saturday in Constantine (431 km east of Algiers), on the last day of the 1st International pharmacy, parapharmacy, health and well-being show (SAIDALYA). This cooperation agreement signed between the pharmaceutical operators of Algeria, Tunisia, Ivory Coast, Burkina Faso and Senegal aims mainly at "developing throughout Africa all the activities relating to the pharmaceutical field at the training, information and commercial levels," said the event's organizer Yacine Fersado. This "cooperation" network, expected to "significantly" expand, will allow the African countries to "boost" their pharmaceutical industries considered today as "a financial windfall of a major importance," according to Fersado, insisting on the urgent need to "coordinate" all the actions to achieve the development objectives outlined for this purpose.
Why Africa’s health goals matter. Global Fund pledges $12.9bn to fight Malaria, AIDS & TB. Private Spending on Healthcare [2013 Data] by Country. Donors set aside $24b for African health. Africa’s real crisis is heart disease. In 2015, the United States spent $7.5 billion, more than three-quarters of its global health budget, to fight Aids, tuberculosis and malaria. These, after all, are the “big three” infectious diseases, and they’ve ravaged developing-world populations. Supercomputing Genetic Medicine in Africa. The National Center for Supercomputing Applications at the University of Illinois at Urbana-Champaign is helping change the way genetic medicine is researched and practiced in Africa. Computers vs Ebola: Scientists use big data to predict future disease hotspots. Machine learning reveals undiscovered Ebola-carrying bats. Instant HIV, hepatitis diagnostic machine boost testing in Africa. Improved healthcare delivery models across Africa transform industry, says Frost and Sullivan - Cape Business News.
The Growth of Cosmetic Surgery in Africa - Face2face Africa. In the lab: Six innovations scientists hope will end malaria. 'Virtual doctors' helping patients in Zambia. Africa will be Short Six Million Healthcare Workers by 2030, But it Can Still Achieve its Commitment of Universal Health Care if it Takes Action Now. Six pays africains pourraient éradiquer le paludisme d'ici 2020. Africa: Fast Food, Flashy Cars and Shopping Malls - Africa Hurtles Into Obesity Crisis. Africa: Novartis Expands Partnership with Medicines for Malaria Venture to Develop Next-Generation Antimalarial Treatment.
Santé : cliniques privées et hôpitaux publics s'allient en Afrique. Australian scientists say a breath test could diagnose malaria. Cancer is on the rise in Africa just as some of the few radiotherapy centers fall apart — Quartz. Africa: More Africans Are Accessing Health Care - but States Still Have Work to Do. Africa: New Partnership in Cancer Fight Launched. Rising Life Expectancy in Africa: What Does It Mean? - Face2face Africa. 14% of Africans pay bribe for health care - Survey. Africa: Digital Healthcare Revolution beckons. Forbes Welcome. Africa: Diabetes - Changing Lifestyles Affect Health in Africa. Africa’s real crisis is heart disease.
Africa: Plea for Treaty On Drug Research. Africa: Why a New Vaginal Ring Could Be a Game-Changer in HIV Prevention. #MCIA 16: How a vaccine is improving the African child's health. Study Detects Gut Microbiome Differences in African Agriculturist, Hunter-Gatherer Populations. Africa: Watch Out for Child Obesity - Africa's Children Aren't Just Hungry. New Malaria Test, illumigene® Malaria, Sets a New Gold Standard for Diagnosis Nasdaq:VIVO.
Africa: Stillbirths Down By Quarter Since 2000. Africa: Ebola, Malaria Vaccines - HIV Treatments Expected in 2016. Pour mieux vous soigner en Afrique, allez prioritairement en Egypte et en Afrique du Sud. All in Africa: The World’s 13 Highest-Mortality Countries. Experts strive to jointly regulate medicines in Africa. Africa faces up to obesity epidemic. Africa: HIV Drugs for Babies Slashes Breastfeeding Risk. Africa: Innovative pro-poor healthcare delivery models making strides in Africa : The case of the Healthy Heart Africa Programme. Tanzania: African Scientists Develop Methods to Avert Outbreaks. East Africa: Researchers Burn the Midnight Oil to Develop HIV Vaccine. Africa: Cancer Soars in Global South. Ethiopia has cracked the problem of rural health, but its workers feel stuck. Genes that protect African children from developing malaria identified. HIV/AIDS infections dropping in Africa.
'AIDS is now the biggest killer of African teens' - The Network of Forward Moving People. Africa: Breakthrough Brings Cost of HIV Treatment to Under $100 Per Patient Per Year. Fastcoexist. Africans need to make their mark in the pharmaceutical industry boom. Africa: Deadly Meningitis Strain Virtually Eliminated in Much of Africa - Study - allAfrica.com. Africa: How Drones Can Improve Healthcare Delivery in Developing Countries - allAfrica.com. Trends shaping pharma industry in Africa. Africa highlighted as a market with high potential for pharma industry … 10 Impressive, World-Class African Hospitals. Malaria cases in Africa are soaring. Here’s the surprising reason why. Socking it to malaria just the start for Africa's new science alliance. Top 10 healthcare apps for Africa. Mosquito-hunting spiders could help fight deadly malaria - SciDev.Net Sub-Saharan Africa. High-dose vitamin D could help fight HIV/AIDS - SciDev.Net Sub-Saharan Africa. L’anneau vaginal capable de protéger du HIV, c’est pour bientôt.
A Milestone in Africa: No Polio Cases in a Year. Africa agency to offer insurance against Ebola. Schizophrénie : un nouveau traitement venu d'Afrique. Healing plants inspire new compounds for psychiatric drugs. Creating a contact lens that suits the African eye. Africa is within reach of being declared a polio free region. Roche's Expansion In Africa Is a Good Long Term Move, Though The Immediate Opportunity is Small. Bart Knols: Waging war on mosquitoes. Investing in health, investing in Africa. Africa awaits first malaria vaccine candidate approval - SciDev.Net Sub-Saharan Africa.
Viagra may prove a valuable weapon against malaria.