Drugs
Mouse Party
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1999 BBC News Health: Alcohol benefits debunked Moderate alcohol consumption has no positive effect on health 2005 CDC Study Skeptical on Moderate Drinking's Heart Benefit Moderate alcohol consumption should not be recommended 2005 Alcohol's health benefits doubted Gains are likely outweighed by the harm
Alcohol
Psychedelics
The 5 Greatest Things Ever Accomplished While High
Cracked.com's new book is now on sale . What follows is one of the classic articles that appear in the book, along with 18 new articles that you can't read anywhere else. Any dreadlocked white guys finding this article after Googling "Drugs Rule" should know that we've given this list about drugs a rule.
The mammalian 5-HT 2A receptor is a subtype of the 5-HT 2 receptor that belongs to the serotonin receptor family and is a G protein-coupled receptor (GPCR). [ 1 ] This is the main excitatory receptor subtype among the GPCRs for serotonin (5-HT), although 5-HT 2A may also have an inhibitory effect [ 2 ] on certain areas such as the visual cortex and the orbitofrontal cortex . This receptor was first given importance as the target of serotonergic psychedelic drugs such as LSD . Later it came back to prominence because it was also found to be mediating, at least partly, the action of many antipsychotic drugs, especially the atypical ones. 5-HT 2A may be a necessary receptor for the spread of the human polyoma virus called JC virus . [ 3 ] Downregulation of post-synaptic 5-HT 2A receptor is an adaptive process provoked by chronic administration of SSRIs and classical antipsychotics. Deceased suicidal and otherwise depressed patients have had more 5-HT 2A receptors than normal patients.
5-HT2A Receptor
The War on Drugs is a War on You
Posted by Michael Boldin by Michael Boldin The drug war is based on a repugnant assertion: that you do not have ownership over your own body; that you don’t have the right to decide what you’ll do with your body, with your property and with your life. The position of the drug warriors is that you should be in jail if you decide to do something with your body that they don’t approve of. This is an abomination of everything that America is supposed to stand for. As long as this country continues the drug war, you are not free.
Cannabis
What Caffeine Actually Does to Your Brain
For all of its wild popularity, caffeine is one seriously misunderstood substance. It's not a simple upper, and it works differently on different people with different tolerances—even in different menstrual cycles. But you can make it work better for you. Photo by rbrwr .5 Amazing New Experimental Drugs
I'm the resident Alternative Lifestyle Specialist around here (which is what I keep asking my boss to call me instead of "drug-addled wreck of a human being"), so when new pharmaceutical trends sweep through the United States like Daniel Larusso's leg, it's up to me to cover them. I'm talking about a new class of drugs called "nootropics" - though "new" is a subjective term. They've been around for decades now, but they're only just recently taking off with a drastic rise in casual use. The truly great thing about nootropics is that, by and large, they're utterly harmless; they're meant to boost mental function with little to no side effects--regardless of dosage. Because of this, most of them are available freely on the market as "supplements." So I'll be testing out and reviewing the five most popular ones.
It's a not-so-dirty little secret that most of today's leading meditation teachers were interested in drugs. By "drugs," of course, I don't mean alcohol or Oxycontin, but rather that subset of chemicals which our society has deemed unfit for human consumption, including cannabis, psilocybin, MDMA, and others. Many of today's leading Buddhist teachers, for example, credit their first taste of altered mind states not to samadhi but to LSD or mushrooms, and almost every spiritual teacher I know (and I know a bunch) smoked pot.
