Technology Review: Videos. Technology Review: A Musical Score for Disease. When set to music, colon cancer sounds kind of eerie.
That’s the finding of Gil Alterovitz, a research fellow at Harvard Medical School who is developing a computer program that translates protein and gene expression into music. In his acoustic translation, harmony represents good health, and discord indicates disease. At any given time in each of our cells, thousands of genes are churning out their molecular products while thousands more lie senescent.
The profile of which genes are on versus off is constantly changing–with specific diseases such as cancer, for example. Searching for a more simplified way to represent the complex library of information inherent in gene expression, Alterovitz decided to represent those changes with music. The first step in the gene-to-sound conversion was to pare down multiple measurements to a few fundamental signals, each of which could be represented by a different note.
Gb-2007-8-5-405.pdf (application/pdf-object) ThyAhomosapiens.mid (audio/midi-object) Dnaarticle. In seeking new interpretations of genetics, a number of scientists and musicians have generated musical sequences based on patterns that can be found in DNA.
As the field of genomics expands, so have the methods of arriving at musical representations of DNA multiplied. The present paper offers a new approach that concentrates on the element of rhythm. Most musical interpretations of DNA to date have been concerned with the possible tonal qualities of the four nucleic acids that make up the genetic code, with an emphasis on the proteins that are created from them. As an alternative, one may look to the natural processes during which the DNA strands are dissociated, or broken apart. During replication and transcription, the strands dissociate sequentially and so raise the possibility of a characteristic temporal event.
The basic processes and elements of DNA dissociation are well known. In order to separate the opposing DNA strands, the H-bonds must be broken. 1. Our Sound Universe: the Music of Susan Alexjander, aka: Susan Alexander. Fluid The Measure of All Things by Rebecca Kamen LISTEN (Mac users: Safari or Chrome) MP3 9.3MB Click to listen other browsers: (Safari right click to download into iTunes) (Please listen on good speakers, or with headphones.
Firefox may not be the best choice of browser for .mp3 files.) In-depth article: Fluid, The Soundtrack Creation Fluid was created for a gallery installation of sound and visuals, in collaboration with sculptor Rebecca Kamen: Joan Hisaoka Healing Arts Gallery at Smith Center, Washington, DC April 13th-May 26, 2012. Fluid reflects our visions of how light, shapes and rhythms inform our body as it communicates with itself, the Earth and the overall Matrix of life. The soundtrack for Fluid uses the cranial-sacral model of healing. Totallyhugebook1.pdf (application/pdf-object) A song in praise of peptide palindromes. [Leukemia. 1993] - PubMed result.
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