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Meat, Fat and the Gut Microbiome

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Why Fish is Great for the Gut Microbiome. Is High Fat Healthy for the Gut Microbiota? RHR: Are High-Fat Diets Bad for the Microbiome? Those in the Paleo and ancestral health communities have a tendency to follow high-fat, low-carb diets. After all, when you cut out grains, you naturally cut out a lot of carbs. But are there downsides? What happens to our microbiome on a high-fat diet?

If you’ve been following my work for a while, you won’t be surprised when I say, “It depends.” In this episode we discuss: Questions to ask about these findingsHigh fiber and its impact on high-fat dietsLow-carb, low-fiber diets can be detrimentalEach person responds to high-fat diets differently Chris Kresser: Hey, everybody, Chris Kresser here.

Carrie: Hi, Chris. Chris: Thanks so much for sending your question in, Carrie. Questions to ask about these findings The first question is whether these studies are in mice or in humans. High fiber and its impact on high-fat diets Here’s another one. Here’s another one. Don’t worry if you didn’t get all that. Low-carb, low-fiber diets can be detrimental Following a high-fat diet? I hate spam too. How Fats Influence the Microbiome. “This paper, which had nicely controlled conditions, demonstrated that type of fat is really important for shaping microbial communities and their functional dynamics, which in turn impact our health,” said Vanessa Leone, a postdoc studying host-microbe interactions at the University of Chicago who was not involved in the study.

“It had been previously shown that switching to a high-fat diet markedly and rapidly alters the gut microbiota, but this study goes farther to show that feeding different types of fat result in very different composition of gut microbiota,” Sean Davies, a professor of pharmacology at Vanderbilt University in Nashville, Tennessee, wrote in an email to The Scientist. Davies, too, was not involved in the research. A team led by investigators at the University of Gothenburg in Sweden fed mice diets with the same total number of calories, but some mice received nearly all their fat intake from fish oil, while others received large amounts of lard.

R. Lactobacillus vs. Oscillibacter! Does (Saturated) Fat Tip The Scale Towards Leaky Gut, Obesity & Visceral Inflammation? - SuppVersity: Nutrition and Exercise Science for Everyone. Having tons of subcutaneous fat is certainly unaesthetic, but as science would have it, probably more healthy than a mediocre amount of superfluous visceral fat.

But why is that? I mean, what makes the difference? It cannot be the location, can it? Well, a recently published study on metabolic dysfunction in diet induced diabetic mice suggests that it could be as simple as that (Lam. 2012). You cannot spot reduce fat, but can you "spot inflame" it? In order to assess the effects of normal vs. high fat (60%) diets on gut Permeability and microbiota the Yan Y Lam and his (or her?) What are amyloid A3 and adiponectin? While these are results we have seen in countless of studies before, the interesting part of the study began with the collection of stool samples in the last three days and the "termination" of the animals at the end of the 12-week study period.

Causal, corollary, chicken or egg? So happy to be a "Kraut" ;-) Different types of dietary fat affect obesity through changes to the microbiome — The American Microbiome Institute. Dietary fat comes in many in many different forms, such as saturated fats that come from foods like lard, and polyunsaturated fats that come from foods like fish oil. It is generally believed that saturated fats lead to inflammation and obesity, but that polyunsaturated fats are healthier, and can counteract inflammation and promote healthy metabolism. The role of the microbiome in mediating these effects is still unknown, but is beginning to be elucidated. A team of researchers from Sweden, Belgium and Denmark showed that the lipids themselves alter the microbiome, which induces the characteristic inflammation associated with ingesting saturated fats. Their results were published in the journal Cell Metabolism. The scientists fed groups of mice identical diets that only differed in the type of fat that was consumed: lard composed of saturated fats, and fish oil composed of polyunsaturated fat.

Saturated Fat Kills Gut Bacteria & Modifies Genes in the Distal Small Intestine - Another Reason Why We Get Fat? Plus: Bacteria, Fiber, SCFA, GLP-1 & PYY Revisited - SuppVersity: Nutrition and Exercise Science for Everyone. I guess some of you have already noticed that I was (and probably am now, again) somewhat behind, as far as answering your questions, comments an wise remarks are concerned.

Actually it is still more of a coincidence that today's SuppVersity news, which, as you see is not an Adelfo Cerame post (don't forget to keep the fingers crossed for him! This is his weekend!) , could actually be interpreted as my somewhat lengthy response to a comment from Vincente on the effects of GLP-1 on chocolate preference in rats and an interesting hypothesis of his, on how this could all relate to my previous post on the fat burning effects of GLP-1 ("Eat More, Burn More and Lose Fat Like on Crack with GLP-1!?

"). What, that was Vincente's reasoning, what, if those obese individuals had just messed up their gut bacteria an would lack those beneficial bacteria, which convert the fiber and resistant starch that makes it through your small intestine, right down into your long one to short chain fatty acids? Short-Term Overfeeding with Dairy Cream Does Not Modify Gut Permeability, the Fecal Microbiota, or Glucose Metabolism in Young Healthy Men | The Journal of Nutrition. Skip to Main Content Sign In Register Close Advanced Search Online ISSN 1541-6100 Print ISSN 0022-3166 Copyright © 2018 American Society for Nutrition Connect Resources Explore Oxford University Press is a department of the University of Oxford. Close. Omega-3 intake linked to greater gut microbiome diversity.

The study, published in Nature’s Scientific Reports​, examined the gut microbiome of a large cohort of middle-aged and elderly women by comparing the diversity and abundance of ‘good’ bacteria against their intake of omega-3 fatty acids and their blood serum levels of omega-3 fatty acids. Led by Dr Ana Valdes from the University of Nottingham, the team found that women who had a higher intake of omega-3 and a higher omega-3 index had more diverse gut microbiome – which is associated with a number of health benefits, including lower risk of diabetes, obesity and inflammatory gut diseases like colitis or Crohn’s. “Our study is the largest to date to examine the relationship between omega-3 fatty acids and the composition of the gut microbiome,”​ said Valdes. The team used data from a cohort of 876 volunteer women that previously been used to investigate the human genetic contribution to the gut microbiome in relation to weight gain and disease.

Microbiome data​ Resistant Starch and Red Meat | The Potato Hack Chronicle. The Paleo Community is once again backed into a corner, defending “meat.” The World Health Organization recently released a report that says: Overall, the Working Group classified consumption of processed meat as “carcinogenic to humans” (Group 1) on the basis of sufficient evidence for colorectal cancer. Additionally, a positive association with the consumption of processed meat was found for stomach cancer. The Working Group classified consumption of red meat as “probably carcinogenic to humans” (Group 2A).

In making this evaluation, the Working Group took into consideration all the relevant data, including the substantial epidemiological data showing a positive association between consumption of red meat and colorectal cancer and the strong mechanistic evidence. Consumption of red meat was also positively associated with pancreatic and with prostate cancer. According to the World Health Organization: Processed meats cause cancer; Cooked red meat probably causes cancer. Or: Conclusion Tim. Chowing Down On Meat, Dairy Alters Gut Bacteria A Lot, And Quickly.

To figure out how diet influences the microbiome, scientists put volunteers on two extreme diets: one that included only meat, egg and cheese and one that contained only grains, vegetables and legumes. Morgan Walker/NPR hide caption toggle caption Morgan Walker/NPR To figure out how diet influences the microbiome, scientists put volunteers on two extreme diets: one that included only meat, egg and cheese and one that contained only grains, vegetables and legumes.

Looks like Harvard University scientists have given us another reason to walk past the cheese platter at holiday parties and reach for the carrot sticks instead: Your gut bacteria will thank you. Switching to a diet packed with meat and cheese — and very few carbohydrates — alters the trillions of microbes living in the gut, scientists report Wednesday in the journal Nature. The change happens quickly. "I mean, I love meat," says microbiologist Lawrence David, who contributed to the study and is now at Duke University. Red meat, atherosclerosis, and the microbiome — The American Microbiome Institute. Red meat is rich in a molecule called L-carnitine. The researchers fed this molecule to germ free mice, mice on antibiotics, and control mice and discovered that those with a healthy microbiome produced high levels of TMAO. They proved a new pathway for this conversion, via an intermediate molecule called γ-Butyrobetaine, by detecting genes for its production.

They then proved that γ-Butyrobetaine alone could be converted to trymethyl-amine (TMA) by the microbiome. (TMA is the precursor to TMAO before being acted on by the liver.) Next, they discovered that a diet consisting of L-carnitine or γ-Butyrobetaine shifted the microbiome to be enriched in bacteria that could efficiently break them down to convert them to TMAO. Finally, they gave two groups of mice a diet high in γ-Butyrobetaine to demonstrate the microbiome’s importance in atherosclerosis. This paper provides a definitive link between the actions of the microbiome and atherosclerosis. Rarity of colon cancer in Africans is associated with low animal product consumption, not fiber. Microbiome and Meat: Let the Silly Season Begin | Mr. Heisenbug. I’ve been meaning to get this one out of the way.

As the microbiome and the importance of our gut microflora composition begins to get more attention, it will become, as all things do, subject to preconceived notions and biases about health. And perhaps nothing is as preconceived and biased in the world of diet and health as the idea that intake of meat and its associated saturated fat are inherently unhealthy. Case in point. A writer for The Guardian reports on having his gut bacteria sequenced and drops a couple of misconceptions that really need to be cleared up: At the broadest level, the phylum level, my microbiota, in common with everyone else’s, was dominated by two types: firmicutes and bacteroidetes. And: Again these were positive results. But by then he had managed to make a blind prediction of my diet that was uncannily accurate. Where to even start? Tell me how, exactly, one would see “evidence” of high or low meat consumption in this scenario.

Theoretically. — Heisenbug. Different diets can affect C. diff infection and survival — The American Microbiome Institute. We’ve covered the topic of Clostridium difficile infection extensively on this blog. We know that infection of this bacteria (CDI) can be nasty, sometimes even leading to death. A lot of research has been done to find ways to treat the effects of C. diff infection or to find out how the infection is acquired, but few papers have investigated dietary interventions to help treat CDI.

A new study published by PLoS One examined this, studying how different diets, and specifically how protein content of those diets, affected the severity of CDI. 7-8 week old male mice were weighed and separated into five groups, each given a different diet. Mice on the 20% protein diet showed delayed onset disease with a 25% survival rate over 2 weeks. In another part of the study done by the researchers, they chose to examine the presence of four gut microbiota groups ( Firmicutes, Bacteroides, Enterobacteriaceae, and total bacteria), after antibiotics or no antibiotics.