Revista Cubana de Farmacia - Farmacogenética: medicina personalizada. Farmacodivulgación Centro de Investigaciones Biomédicas Instituto de Ciencias Básicas y Preclínicas.
"Victoria de Girón". ISCM-H. Medicina (Buenos Aires) - Farmacogenética/farmacogenómica en la práctica clínica. HapMap Homepage. Genomics > Table of Pharmacogenomic Biomarkers in Drug Labels. Pharmacogenomics can play an important role in identifying responders and non-responders to medications, avoiding adverse events, and optimizing drug dose.
Drug labeling may contain information on genomic biomarkers and can describe: Drug exposure and clinical response variabilityRisk for adverse eventsGenotype-specific dosingMechanisms of drug actionPolymorphic drug target and disposition genes The table below lists FDA-approved drugs with pharmacogenomic information in their labeling. The labeling for some, but not all, of the products includes specific actions to be taken based on the biomarker information. Biomarkers in the table include are not limited to germline or somatic gene variants, functional deficiencies, expression changes, and chromosomal abnormalities.