Protein Data Bank - RCSB PDB. A Structural View of Biology This resource is powered by the Protein Data Bank archive-information about the 3D shapes of proteins, nucleic acids, and complex assemblies that helps students and researchers understand all aspects of biomedicine and agriculture, from protein synthesis to health and disease. As a member of the wwPDB, the RCSB PDB curates and annotates PDB data. The RCSB PDB builds upon the data by creating tools and resources for research and education in molecular biology, structural biology, computational biology, and beyond.
Use this website to access curated and integrated biological macromolecular information in the context of function, biological processes, evolution, pathways, and disease states. A Molecular View of HIV Therapy January Molecule of the Month Nuclear Pore Complex Deposition Preparation Tools Data Extraction Small Molecules Ligand Expo: Search the Chemical Component Dictionary for the IDs of released ligands Data Format Conversion 3D Structure Viewers. National Center for Biotechnology Information. Untitled. КУРС ЛЕКЦИЙ 1999-2000 гг. Основные функции белков. Аминокислотная последовательность определяет пространственную структуру, пространственная структура — функцию. Обратное — неверно. Глобулярные, фибриллярные и мембранные белки. Первичная, вторичная, третичная, четвертичная структура белка. Биосинтез белка; сворачивание белка in vivo и in vitro.
Стереохимия L-аминокислотных остатков. Вторичная структура полипептидов. Фибриллярные белки, их функции и их периодичные первичные и вторичные структуры; a-кератин, b-фиброин шелка, коллаген. Кооперативные переходы. Дных состояний в сворачивании белка. Представление о подходах к предсказанию вторичных и пространственных структур белков по их аминокислотным последовательностям.
Функция белка и его структура. Дного состояния в катализе и ее подтверждение методами белковой инженерии. РЕКОМЕНДОВАННАЯ ЛИТЕРАТУРА (послужившая также источником многих иллюстраций к этим лекциям) Добавлено при редактировании электронного курса лекций: CLC bio: CLC Main Workbench. A comprehensive workbench for advanced DNA, RNA, and protein analyses The functionalities of CLC Main Workbench are used by tens of thousands of researchers all over the world for DNA, RNA, and protein sequence data analysis, such as gene expression analysis, primer design, molecular cloning, phylogenetic analyses, and sequence data management, amongst a wide variety of other features – all wrapped in an intuitive graphical user-interface. CLC Main Workbench is available on Windows, Mac OS X, and Linux platforms. You can make your computer a high performance computing center. You can use CLC Assembly Cell to accelerate reference assembly and de novo assembly of next generation sequencing data.
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