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The Diabetes Blues. Arleen Marcia Tuchman, Professor of History, Vanderbilt University Posted: Tuesday, January 13, 2015, 6:30 AM Lord, I’m sick an’ down Can’t tell my head from my feet Can’t hardly tell my head from my feet Well, I got the sugar diabetes Somebody please. When Delta Blues guitarist and singer Big Joe Williams sang “Sugar Diabetes Blues” on his 1999 album “Going Back to Crawford” (his Mississippi hometown), he was singing about a problem haunting the Delta as well as the nation. Simply put, diabetes means high blood sugar due to a lack of the hormone insulin—either because the pancreas isn’t making it (type 1 diabetes) because the cells in the body aren’t sufficiently responding to it (type 2 diabetes).

The long history of diabetes—its management with insulin since 1922 and a variety of oral drugs since the 1950s, its current prevalence, and the lack of a cure—means there are plenty of movies, novels, guides, websites, and organizations offering insights and information. Down on my knees. VU study shows common diabetes drug can slow chronic kidney disease progression. By Kathy Whitney | Posted on Thursday, Jun. 26, 2014 — 8:54 AM Vanderbilt investigators have demonstrated in two studies that metformin-based treatments delay the onset and progression of chronic kidney disease (CKD) compared with other treatments for diabetes. Metformin is the most commonly used drug to treat diabetes, but there was no evidence demonstrating its effect on kidney disease until now. “This novel finding is highly important because development of chronic kidney disease greatly increases the risk of cardiovascular events and death for patients with diabetes,” said Adriana Hung, M.D., MPH, assistant professor of Medicine.

Hung presented both papers at the American Society of Nephrology annual meeting. The first paper was published in Kidney International and the second in Pharmacoepidemiology and Drug Safety. Patients with CKD have complex metabolic disturbances including insulin resistance and chronic inflammation. Hung is the recipient of the Ronald D. Study reveals risks with early insulin treatment. Prescribing insulin sooner rather than later — an emerging trend in treating people with type 2 diabetes — could do more harm than good, according to a study by Vanderbilt University researchers.

They compared the health of veterans who were either given insulin or an oral medication after their blood sugar levels could no longer be controlled just by metformin — a pill that is the front-line treatment for most diabetics. The veterans who got insulin experienced a 30 percent greater risk for the combined outcome of heart attacks, strokes or death, according to the study published in the Journal of the American Medical Association.

The study compared patients who started insulin after metformin with those who started a group of medicines called sulfonylureas after metformin. Sulfonylureas are a class of drugs sold under generic brands that include glyburide and glipizide. “There’s been controversy regarding diabetes management,” said Dr. Reach Tom Wilemon at Diabetes in the U.S. Source: U.S. Study-reveals-sizable-increase-in-diabetes-among-children. For years doctors have warned of a rising epidemic of diabetes among children. Yet there has been surprisingly little firm data on the extent of this disease among younger Americans. Now a nationally representative study has confirmed that from 2001 to 2009 the incidence of Type 1 and Type 2 diabetes drastically increased among children and adolescents across racial groups.

The prevalence of Type 1 diabetes increased 21 percent among children up to age 19, the study found. The prevalence of Type 2 diabetes among those ages 10 to 19 rose 30 percent during the period. Those are “big numbers,” said Dr. The analysis, published on Saturday in JAMA, the journal of the American Medical Association, includes data from more than three million children younger than 20 in five states — California, Colorado, Ohio, South Carolina and Washington — as well as from selected American Indian reservations. But the new report found the prevalence also has increased among black and Hispanic youths. Study-reveals-sizable-increase-in-diabetes-among-children. Gene mutation may prevent Type 2 diabetes. Best Yogurts to Ward Off Diabetes. Bulletin Today | Personal Health Print It sounds so simple: Eat a couple of low-fat yogurts every week and this could reduce your risk of developing type 2 diabetes by 28 percent, a new British study finds.

And if you also swap out one sugary dessert or fatty snack for an additional container of yogurt, you’ll cut your risk by a whopping 47 percent! Obviously, that’s not all it takes to ward off diabetes. Still, it is intriguing that British researchers looking at diet-disease connections found that people who ate low-fat fermented dairy products, such as yogurt and cottage cheese, several times a week reduced their risk of developing diabetes by nearly a third, compared with those who didn’t eat these foods. >> Sign up for the AARP Health Newsletter The research was part of a larger study looking at diet and risk of cancer among adults ages 40 to 79.

Dietitian G. She also cautions that those at risk for diabetes should choose yogurts with a lower sugar content. Photo: nanisimova/iStock. Ogle Contact Lens To Monitor Diabetes Holds Promise. <br/><a href=" US News</a> | <a href=" Business News</a> Copy Google has come up with another wearable eye device, this time a lens made out of soft contact material that might help diabetes patients keep track of their glucose levels.

The company revealed a functional prototype Jan. 16 that doctors are saying has the potential to replace not only the current continuous glucose monitors implanted under the skin, but perhaps one day even the painful finger-pricking blood tests. The so-called smart lens, a tiny wireless computer chip that contains a glucose sensor and an antenna thinner than a strand of hair, is implanted between soft contact lens material, which is worn on the surface of the eye. The lens is powered by tapping into radio waves in the air and is designed to send data to a smart phone or other device. "Glucose levels change frequently with normal activity like exercising or eating or even sweating. Dr. FDA approves diabetes pill that eliminates excess sugar through urine. Biodegradable scaffold may spur wound healing | Research News @ Vanderbilt. By Bill Snyder | Posted on Thursday, Dec. 19, 2013 — 9:25 AM From left, Scott Guelcher, Ph.D., Jeffrey Davidson, Ph.D., Christopher Nelson and Craig Duvall, Ph.D., showed that an enzyme-blocking molecule released by a biodegradable scaffold can enhance wound healing in a mouse model.

(photo by Susan Urmy) Biomedical and chemical engineers at Vanderbilt University, working with a pathologist, have constructed a sponge-like, biodegradable tissue “scaffold” that releases an enzyme-blocking molecule to indirectly activate endogenous pathways and enhance tissue regeneration and wound healing. If further animal studies confirm the initial findings, the drug-containing scaffold could provide a new approach to healing chronic wounds, which afflict millions of patients with diabetes and other diseases and cost the U.S. health care system more than $25 billion a year, according to one estimate.

The study was supported by National Institutes of Health (NIH) grants EB021750 and AR056138. Massachusetts General Hospital researchers identify identify biomarker to predict diabetes risk. Massachusetts General Hospital researchers identify identify biomarker to predict diabetes risk Study outlines new technique to detect chemical changes in blood 29/Oct/2013 Researchers at the Massachusetts General Hospital Institute for Heart, Vascular and Stroke Care and Vanderbilt Heart and Vascular Institute have found a chemical biomarker in blood that can predict diabetes risk more than a decade before the onset of the disease. Their findings were reported in the October edition of The Journal of Clinical Investigation.

“In the United States, almost 10 percent of the population has diabetes,” says Robert Gerszten, MD, director of clinical and translational research at the MGH Institute for Heart, Vascular and Stroke Care. The study looked at participants in the Framingham Heart Study, which has, for the past 65 years, identified common factors and characteristics in the blood that contribute to cardiovascular disease. Vanderbilt Diabetes in Nashville. Diabetes Self-Management Education Program - Vanderbilt Diabetes in Nashville. Welcome to the Diabetes Self-Management Education Program at Vanderbilt. Our program helps people with diabetes who: • Have not had diabetes for very long• Have had diabetes for a long time but want an update• Need ideas for living a healthier lifestyle• Want to stay healthy and avoid problems that can happen with diabetes To join the program, you'll need a referral from your health care provider.

The American Diabetes Association has recognized our program as meeting national standards for diabetes self-management education and support. The Program You will meet with other diabetes patients to talk about how to take better care of this disease that you have in common.Your group leaders will be registered nurses and registered dietitians who are Certified Diabetes Educators and have worked with diabetes patients for many years.

Here are some of the things that you might talk about in one of our diabetes classes: What is type 1 or type 2 diabetes? What to Bring. Take the JDRF T1D for a Day Text Challenge! Step into the shoes of someone living with type 1 diabetes (T1D) for one day in an eye-opening text campaign made possible through the generous support of Lilly Diabetes. In just a single day, you’ll gain a deeper understanding of the challenges people with T1D face. Sign up today, or any day in November, and you’ll receive multiple text messages over 24 hours from professional snowboarder Sean Busby. Sean has lived with T1D for nine years and has backcountry snowboarded on six continents (including Antarctica!).

Each of his messages will show you what it’s like to manage the blood glucose testing, insulin injections, and dietary choices that T1D requires every day. Hear what Sean has to say about T1D for a Day: Text T1D4ADAY to 63566. . • If you sign up before November 1, your T1D for a Day challenge will begin the morning of November 1. • If you sign up from November 1 through November 30, your T1D for a Day challenge will begin within an hour of registration. Needlogin?type=login&redirecturl=http%3A%2F%2Fwww.tennessean. Tennessean. Researchers identify novel biomarker for diabetes risk. By Kathy Whitney | Posted on Tuesday, Sep. 17, 2013 — 8:22 AM Researchers at the Vanderbilt Heart and Vascular Institute and Massachusetts General Hospital have identified a biomarker that can predict diabetes risk up to 10 years before onset of the disease.

Thomas J. Wang, M.D., director of the Division of Cardiology at Vanderbilt, along with colleagues at Massachusetts General Hospital and Boston University, report their findings in the October issue of The Journal of Clinical Investigation. Thomas J. The researchers conducted a study of 188 individuals who developed type 2 diabetes mellitus and 188 individuals without diabetes who were followed for 12 years as participants in the Framingham Heart Study. “From the baseline blood samples, we identified a novel biomarker, 2-aminoadipic acid (2-AAA), that was higher in people who went on to develop diabetes than in those who did not,” Wang said.

. “2-AAA appears to be more than a passive marker. General News / VU tracking drug’s ability to prevent type 1 diabetes. Vanderbilt’s Eskind Diabetes Clinic has been selected to examine the ability of the drug abatacept to prevent type 1 diabetes (T1D). As part of the TrialNet consortium, Vanderbilt will be one of 14 North American sites observing the effects of the drug in people at high risk to develop T1D. T1D, formerly called juvenile diabetes, is an autoimmune disease that is predominant in the younger population and has a strong genetic component. The study is seeking participants between the ages of 6 and 45 whose antibody screening results indicate they have a strong likelihood of developing T1D. “People often think that screening for type 1 diabetes risk factors is unimportant because there is currently nothing that can be done to mitigate their risk level for type 1 diabetes,” said William Russell, M.D., Cornelius Vanderbilt Professor of Pediatrics, director of Pediatric Endocrinology and Diabetes at Monroe Carell Jr.

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/^((29([-\/.]?) /^((02([-\/.]?) /^(((\d{2}([13579][26]|[2468][048]|04|08)|(1600|2[048]00))([-\/.]?) /^[-+]? /^[a-z]+$/i. Antipsychotic drug use in children for mood/behavior disorders increases type 2 diabetes risk | Research News @ Vanderbilt. By Carole Bartoo | Posted on Thursday, Aug. 22, 2013 — 1:00 PM Prescribing of “atypical” antipsychotic medications to children and young adults with behavioral problems or mood disorders may put them at unnecessary risk for type 2 diabetes, a Vanderbilt University Medical Center study shows. Young people using medications like risperidone, quetiapine, aripiprazol and olanzapine led to a threefold increased risk of developing type 2 diabetes within the first year of taking the drug, according to the study published Aug. 21 in the journal JAMA Psychiatry. While other studies have shown an increased risk for type 2 diabetes associated with the use atypical antipsychotic medications, this is the first large, well-designed study to look at the risk in children, said Wayne A.

Ray, Ph.D., professor of Preventive Medicine, and senior author of the study. State-provided, de-identified medical records were examined for TennCare youths ages 6-24 from 1996 through 2007. New service helps patients keep glucose levels on track. By Carole Bartoo | Posted on Thursday, Jul. 11, 2013 — 9:24 AM Ann Hackett, MSN, right, talks with patient Gwendolyn English about managing her blood sugar levels while English’s husband, Allen, and daughter, Monique Roberts, look on.

(photo by Susan Urmy) Following her successful heart valve surgery at Vanderbilt, Gwendolyn English and her family faced a long journey home to Florida. Her family was concerned about the trip, because English has diabetes and her blood sugar levels had been fluctuating erratically. “We were really worried about the drive home. Ann Hackett, MSN, an adult nurse practitioner, provided specialized diabetes care to English.

“We are well equipped to handle all levels of care, from patients with insulin pumps to those on dialysis or intravenous insulin. Increasingly at Vanderbilt, experienced advanced practice nurses are being hired to provide intensive attention to inpatients with multiple, complex health conditions. Type 1 diabetes vaccine shows promise in early study: researchers. Type 1 Diabetes TrialNet at Vanderbilt - FAQs. Diabetes costs nation $245 billion annually, study says. Discovery Lecture explores brain’s sensitivity to insulin. Harvard’s Kahn set for Discovery Lecture. Needlogin?type=login&redirecturl=http%3A%2F%2Fwww.tennessean.

Needlogin?type=login&redirecturl=http%3A%2F%2Fwww.tennessean. Does Santa Check My Blood Sugars? Study seeks new ways to help teens manage type 1 diabetes. Commonly prescribed oral diabetes drug offers cardiac benefits. Diabetes Notification System to Improve Perioperative Outcomes - Beans Could Help Control Blood Pressure, Reduce Heart Risks For Diabetes Patients: Study. Researchers find that diabetes drug could be effective in treating addiction. Needlogin?type=login&redirecturl=http%3A%2F%2Fwww.tennessean.com%2Fapps%2Fpbcs. Psoriasis Linked to Diabetes. News and Events / General News / Diabetes can’t hold back Little League champion. My Health Chat: Advances in Diabetes Research. Vanderbilt University Medical Center. Family members can often sabotage diabetes care: study (06/14. For Patients - My Health Chat. Diabetes research at VU bolstered by federal grant (04/5. To Combat Diabetes, Weight Loss Surgery Works Better Than Medicine, Studies Find.

University Medical Center - Vanderbilt researchers find blame game doesn’t help obese patients. Early study hints at fat as potential diabetes treatment (03/1. Twins key to juvenile diabetes study at VU. Nashville woman loses 10 dress sizes, diabetes. Large Drop In Leg And Foot Amputations Among Adult Diabetics, CDC. Aliquots — research highlights from VUMC laboratories (01/19. Did Paula Deen's diet cause her diabetes? Diabetes trial sets bar high for retaining research subjects (01/6. Families await artificial pancreas until cure for Type 1 diabetes found. Initiative to help ‘translate’ diabetes research advances (10/20. VUCast: Future Diabetes Vaccine? Impact of diabetes, obesity on glioma patients studied (09/8. New IOM study probes long-term impact of vaccines (08/25. Gestational diabetes program goal is healthy babies, moms (08/25.

Clinical trial seeks to halt type 1 diabetes in its tracks (08/11. VUMCdiabetes. Tackling Diabetes | Hope. Tight blood-sugar control studied to prevent progression of diabetes (06/9. Weight loss surgery cures diabetes in some cases. Victoria's Story. NBC Nightly News with Brian Williams: News and videos from the evening broadcast.