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RETRACTED: Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize

RETRACTED: Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize
This article has been retracted: please see Elsevier Policy on Article Withdrawal ( The journal Food and Chemical Toxicology retracts the article “Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize,” which was published in this journal in November 2012. This retraction comes after a thorough and time-consuming analysis of the published article and the data it reports, along with an investigation into the peer-review behind the article. The Editor in-Chief deferred making any public statements regarding this article until this investigation was complete, and the authors were notified of the findings. Very shortly after the publication of this article, the journal received Letters to the Editor expressing concerns about the validity of the findings it described, the proper use of animals, and even allegations of fraud. Many of these letters called upon the editors of the journal to retract the paper.

http://www.sciencedirect.com/science/article/pii/S0278691512005637

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SCIENTIFIC REPORTS 03/09/18 Comments on two recent publications on GM maize and Roundup Two studies recently published in Scientific Reports1,2 contain a number of questionable issues related to the experimental design and the interpretation of the obtained data. We here point these out and discuss why caution about the far-reaching conclusions presented in the two studies is necessary. The first study (here called the “GM maize report”) claims that genetic transformation process caused metabolic disturbances in genetically modified (GM) NK603 Roundup-tolerant maize, questioning the compositional similarity of this cultivar to a non-GM control cultivar1. The second study (here called the “Roundup report”) reports that exposure of rats to an ultra-low dose of the glyphosate-based herbicide Roundup were found to cause significant metabolome and proteome changes allegedly indicative of liver dysfunction2. Both reports are based on samples collected from an earlier two-year study3,4.

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