Joe Rogan and Duncan Trussell on the Importance of Psychedelics in 2012. Ketamine. Ketamine. Overview : Ketamine is a dissociative anesthetic for human and veterinary use.
Its hydrochloride salt is sold as Ketanest, Ketaset, and Ketalar, or on the street as Special K. Pharmacologically, ketamine is classified as an NMDA receptor antagonist, and like other drugs of this class such as tiletamine, memantine, and phencyclidine ( PCP ), induces a state referred to as "dissociative anesthesia. " Ketamine. INTENSITY: 10 - Infinity MATERIAL: Ketamine is a general anesthetic manufactured by Parke Davis and marketed as Ketalar.
It is also distributed by several smaller pharmaceutical companies. The Parke Davis Ketamine comes in a multi-use sealed vial, generally containing 500 mg. NMDA receptor. Stylised depiction of an activated NMDAR.
Glutamate is in the glutamate-binding site and glycine is in the glycine-binding site. Allosteric sites that would cause inhibition of the receptor are not occupied. LSD (Acid) LSD History Comic. History of LSD. The psychedelic drug (or entheogen) lysergic acid diethylamide (LSD) was first synthesized by the Swiss chemist Albert Hofmann in the Sandoz (now Novartis) laboratories in Basel, Switzerland on November 16, 1938. It was not until five years later on April 16, 1943, that the psychedelic properties were found. Discovery Albert Hofmann, born in Baden, Switzerland, joined the pharmaceutical-chemical department of Sandoz Laboratories, located in Basel as a co-worker with professor Arthur Stoll, founder and director of the pharmaceutical department. He began studying the medicinal plant squill and the fungus ergot as part of a program to purify and synthesize active constituents for use as pharmaceuticals.
Project MKULTRA. Declassified MKUltra documents The scope of Project MKUltra was broad, with research undertaken at 80 institutions, including 44 colleges and universities, as well as hospitals, prisons and pharmaceutical companies. The CIA operated through these institutions using front organizations, although sometimes top officials at these institutions were aware of the CIA's involvement. As the Supreme Court later noted, MKULTRA was: concerned with "the research and development of chemical, biological, and radiological materials capable of employment in clandestine operations to control human behavior.
" The program consisted of some 149 subprojects which the Agency contracted out to various universities, research foundations, and similar institutions. At least 80 institutions and 185 private researchers participated. Because the Agency funded MKULTRA indirectly, many of the participating individuals were unaware that they were dealing with the Agency. Welcome to the DMT-Nexus. LSD Treatment for Alcoholism. Erika Dyck* * Department of History and Classics/Division of Studies for Medical Education, 2–2 Tory Building, University of Alberta, Edmonton, Alberta, T6G 2H4, Canada.
E-mail: Erika.firstname.lastname@example.org In the 1950s, researchers in the Canadian province of Saskatchewan began treating alcoholics with d-lysergic acid diethylamide (LSD) and achieved significant rates of recovery. Psychiatrists, including Humphry Osmond who coined the term ‘psychedelic’ while working in Saskatchewan, believed that the successful treatment of alcoholism with biochemical means would scientifically prove that the condition was a disease and not the result of a weak or immoral character. Peyote (Mescaline) Peyote (Mescaline) Peyote is Schedule I in the United States.
This means it is illegal to manufacture, buy, possess, or distribute without a DEA license, unless it is being used as part of “bonafide religious ceremonies” as per 42 USC §1996a. Addictive Potential: None Emergency Room Visits Yearly: Unknown. Mescaline. Mescaline (3,4,5-trimethoxyphenethylamine) is a Schedule I in the United States.
This means that it is illegal to manufacture, buy, possess, or distribute without a DEA license. Addictive Potential: None Emergency Room Visits Yearly: Unknown. Mescaline. INTENSITY: 3 to 8 for most experiences.
MATERIAL: Mescaline is a naturally occurring psychedelic found in several cactus species, most notably, Peyote(Lophophora williamsii) and San Pedro (Trichocereus pachanoi). Several other members of the trichocereus family also contain mescaline. Mescaline belongs to a family of compounds known as phenethylamines, making it quite distinct from the other major psychedelics which belong to the indole family. LSD, psilocybin, harmaline, and DMT are all indoles. The Plant with the Answer. I am a male (vintage hippy) who has had a fair share of psychadelic experiences in my time.
None, however could equal up to the life-changing trip I experienced after ingesting 'the divine catus'. It was saturday in El Paso,Texas. I was out of the house by 6 o'clock looking for my well known friend, lysergic acid diethylamide. Now up until this point I had never had a problem finding acid. Psilocybin (Magic Mushrooms) Psilocybin. Psilocybin is Schedule I in the United States. This means it is illegal to manufacture, buy, possess, or distribute without a DEA license. Not available by prescription. Fresh and dried psilocybin mushrooms are considered containers of Psilocybin, making them illegal to possess as well. Addictive Potential: None. Psilocybin Mushrooms The Extraterrestrial Inflitration of Earth?
INTENSITY: 3 to 7 for most experiences. MATERIAL: There are dozens of species of mushrooms which contain the psychoactive alkaloids psilocybin/psilocin in active amounts. 99% of the psilocybin mushrooms I've seen sold on the underground market are the variety known as Psilocybe cubensis (also called Stropharia cubensis), and dosage levels discussed below pertain to this variety. Some species of psilocybin mushrooms contain up to 10 times as much psilocybin by weight as cubensis, producing an equivalent experience at a much lower dose. HISTORY: The use of psilocybin mushrooms can be traced back thousands of years. Shroomery.
Psilocybin and the Concept of Natural Intelligence. In this article, I examine some of the new modes of thinking catalysed by a traditionally esteemed shamanic agent, namely the psilocybin mushroom. I will argue that psilocybin can potentiate an eco-psychological experience in which an intelligent aspect to Nature can be directly ascertained. I will further argue that such an experience, such an insight into the intelligence inherent within Nature, has a significant curative role to play in our currently beleaguered relationship with the biosphere.
An Ivy Trail Leads the Way. Seeking the Magic Mushroom. On the night of June 29-30, 1955, in a Mexican Indian village so remote from the world that most of the people still speak no Spanish, my friend Allan Richardson and I shared with a family of Indian friends a celebration of "holy communion" where "divine" mushrooms where first adored and then consumed. The Indians mingled Christian and pre-Christian elements in their religious practices in a way disconcerting for Christians but natural for them. The rite was led by two women, mother and daughter, both of them curanderas, or shamans. The proceedings went on in the Mixeteco language. MDMA (Ecstasy) Ecstasy; E; X; XTC; Rolls; Beans; Adam; Molly Euphoric Empathogen; Stimulant; Phenethylamine 3,4-methylenedioxymethamphetamine MDMA is one of the most popular recreational psychoactives, most commonly sold in the form of "ecstasy" tablets.
It is known for its empathogenic, euphoric, and stimulant effects, and has also been used in psychotherapy. Ecstasy tablets are notoriously impure, often containing chemicals other than MDMA. MDMA Vault : In the Name of Science: Prior Exposure to MDMA May Block High-Dose Neurotoxicity. Ecstasy. MDMA Main Page. Alexander Shulgin on MDMA. Brain on Ecstasy. Study: Ecstacy (MDMA) Does NOT Cause Drain Bamage! Breaking Convention: MDMA Debate. MDMA Preloading/Postloading Regimin. 5-HTP before Ecstasy. Health - 5-HTP & ecstasy. Ecstasy & 5-HTP - 5-HTP can ruin Ecstasy - 607.
Nice Things to do On E. DMT. Nuerosoup: DMT. DMT ~ Water Spirit. DMT Candy for the Mind. Terence McKenna on Entheogens. 2C-B (2CB) Vault. 2C-B. Harmala Alkaloids. Nuerosoup: 2C-B. 2C-B. Brief History. Psychedelic Research of the 1950's and 1960's. Psychedelic Reality. Further Explorations. Psychedelic Safety. Working with Difficult Psychedelic Experiences. Trip Guide. Avoid Bad Trips. Combinations.