Joe Rogan and Duncan Trussell on the Importance of Psychedelics in 2012
Ketamine Overview : Ketamine is a dissociative anesthetic for human and veterinary use. Its hydrochloride salt is sold as Ketanest, Ketaset, and Ketalar, or on the street as Special K. Pharmacologically, ketamine is classified as an NMDA receptor antagonist, and like other drugs of this class such as tiletamine, memantine, and phencyclidine ( PCP ), induces a state referred to as "dissociative anesthesia."
Ketamine INTENSITY: 10 - Infinity MATERIAL: Ketamine is a general anesthetic manufactured by Parke Davis and marketed as Ketalar. It is also distributed by several smaller pharmaceutical companies. The Parke Davis Ketamine comes in a multi-use sealed vial, generally containing 500 mg.
Stylised depiction of an activated NMDAR. Glutamate is in the glutamate-binding site and glycine is in the glycine-binding site. Allosteric sites that would cause inhibition of the receptor are not occupied. NMDA receptor
LSD History Comic
History of LSD The psychedelic drug (or entheogen) lysergic acid diethylamide (LSD) was first synthesized by the Swiss chemist Albert Hofmann in the Sandoz (now Novartis) laboratories in Basel, Switzerland on November 16, 1938. It was not until five years later on April 16, 1943, that the psychedelic properties were found. Discovery Albert Hofmann, born in Baden, Switzerland, joined the pharmaceutical-chemical department of Sandoz Laboratories, located in Basel as a co-worker with professor Arthur Stoll, founder and director of the pharmaceutical department. He began studying the medicinal plant squill and the fungus ergot as part of a program to purify and synthesize active constituents for use as pharmaceuticals.
Declassified MKUltra documents The scope of Project MKUltra was broad, with research undertaken at 80 institutions, including 44 colleges and universities, as well as hospitals, prisons and pharmaceutical companies. The CIA operated through these institutions using front organizations, although sometimes top officials at these institutions were aware of the CIA's involvement. As the Supreme Court later noted, MKULTRA was: concerned with "the research and development of chemical, biological, and radiological materials capable of employment in clandestine operations to control human behavior." The program consisted of some 149 subprojects which the Agency contracted out to various universities, research foundations, and similar institutions. At least 80 institutions and 185 private researchers participated. Because the Agency funded MKULTRA indirectly, many of the participating individuals were unaware that they were dealing with the Agency.
Erika Dyck* * Department of History and Classics/Division of Studies for Medical Education, 2–2 Tory Building, University of Alberta, Edmonton, Alberta, T6G 2H4, Canada. E-mail: Erika.firstname.lastname@example.org In the 1950s, researchers in the Canadian province of Saskatchewan began treating alcoholics with d-lysergic acid diethylamide (LSD) and achieved significant rates of recovery. Psychiatrists, including Humphry Osmond who coined the term ‘psychedelic’ while working in Saskatchewan, believed that the successful treatment of alcoholism with biochemical means would scientifically prove that the condition was a disease and not the result of a weak or immoral character. LSD Treatment for Alcoholism
Peyote is Schedule I in the United States. This means it is illegal to manufacture, buy, possess, or distribute without a DEA license, unless it is being used as part of “bonafide religious ceremonies” as per 42 USC §1996a. Addictive Potential: None Emergency Room Visits Yearly: Unknown Peyote (Mescaline)
Mescaline (3,4,5-trimethoxyphenethylamine) is a Schedule I in the United States. This means that it is illegal to manufacture, buy, possess, or distribute without a DEA license. Addictive Potential: None Emergency Room Visits Yearly: Unknown Mescaline
INTENSITY: 3 to 8 for most experiences. MATERIAL: Mescaline is a naturally occurring psychedelic found in several cactus species, most notably, Peyote(Lophophora williamsii) and San Pedro (Trichocereus pachanoi). Several other members of the trichocereus family also contain mescaline. Mescaline belongs to a family of compounds known as phenethylamines, making it quite distinct from the other major psychedelics which belong to the indole family. LSD, psilocybin, harmaline, and DMT are all indoles. Mescaline
The Plant with the Answer I am a male (vintage hippy) who has had a fair share of psychadelic experiences in my time. None, however could equal up to the life-changing trip I experienced after ingesting 'the divine catus'. It was saturday in El Paso,Texas. I was out of the house by 6 o'clock looking for my well known friend, lysergic acid diethylamide. Now up until this point I had never had a problem finding acid.
Psilocybin is Schedule I in the United States. This means it is illegal to manufacture, buy, possess, or distribute without a DEA license. Not available by prescription. Fresh and dried psilocybin mushrooms are considered containers of Psilocybin, making them illegal to possess as well. Addictive Potential: None Psilocybin
Psilocybin Mushrooms The Extraterrestrial Inflitration of Earth? INTENSITY: 3 to 7 for most experiences. MATERIAL: There are dozens of species of mushrooms which contain the psychoactive alkaloids psilocybin/psilocin in active amounts. 99% of the psilocybin mushrooms I've seen sold on the underground market are the variety known as Psilocybe cubensis (also called Stropharia cubensis), and dosage levels discussed below pertain to this variety. Some species of psilocybin mushrooms contain up to 10 times as much psilocybin by weight as cubensis, producing an equivalent experience at a much lower dose. HISTORY: The use of psilocybin mushrooms can be traced back thousands of years.
Psilocybin and the Concept of Natural Intelligence
Seeking the Magic Mushroom
MDMA Vault : In the Name of Science: Prior Exposure to MDMA May Block High-Dose Neurotoxicity
MDMA Main Page
Alexander Shulgin on MDMA
Brain on Ecstasy
Study: Ecstacy (MDMA) Does NOT Cause Drain Bamage!
Breaking Convention: MDMA Debate
5-HTP before Ecstasy
Health - 5-HTP & ecstasy
Experience Vaults: Ecstasy & 5-HTP - 5-HTP can ruin Ecstasy - 607
Nice Things to do On E
Terence McKenna on Entheogens
2C-B (2CB) Vault
Psychedelic Research of the 1950's and 1960's
Working with Difficult Psychedelic Experiences
Avoid Bad Trips