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Home of the Center for RNA Biology Ohio State University has a large concentration of research labs with interests in RNA research . These laboratories constitute an interdisciplinary group focused on the biochemistry, molecular biology, structure and function of RNA.
Most people I talk to haven’t taken a biology class since high school – but try to reach back into the shadowy depths of your inner-high school student and remember the “Central Dogma” of molecular biology - this dogma is what biology is built on, this is geneticist’s and molecular biologist’s bread and butter: DNA encodes bases (ATCG’s) that will be transcribed into messenger RNA (mRNA), this mRNA will be the template that will be translated into proteins. Today a paper in Science challenges this theory – and who better to challenge the stable ground that biologists walk on than RNA. Sticking to the high school theme, RNA is molecular biology’s “bad boy”, the sexy boundary-pushing bad boy that breaks all the rules in all of the right ways.
12 new RNA-Seq experiments have been loaded. Check out E-GEOD-24283 (Deep transcriptional sequencing analysis of human prostate adenocarcinoma and reference samples) for example. Non-differentially expressed genes are back. Try selecting the up/down/non-d.e. option when searching anywhere in the Atlas.
September 15, 2010 – (BRONX, NY) – By constructing a microscope apparatus that achieves resolution never before possible in living cells, researchers at Albert Einstein College of Medicine of Yeshiva University have illuminated the molecular interactions that occur during one of the most important “trips” in all of biology: the journey of individual messenger Ribonucleic acid (RNA) molecules from the nucleus into the cytoplasm (the area between the nucleus and cell membrane) so that proteins can be made. The results, published in the September 15 online edition of Nature , mark a major advance in the use of microscopes for scientific investigation (microscopy). The findings could lead to treatments for disorders such as myotonic dystrophy in which messenger RNA gets stuck inside the nucleus of cells.
Welcome to EteRNA where you help scientists understand life at the cellular level. You play by designing RNAs, tiny molecules at the heart of every cell. If you win the weekly competition, your RNA is synthesized and scored by how well if folds.