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http://www.biomedcentral.com/1471-2105/9/248/ Requirements for an accurate null model An optimal null model preserves all the features of the original data with the exception of the signal under question that needs to be removed efficiently. In our case, the data are multiple alignments of homologous sequences and the signal of interest is an evolved RNA secondary structure.

BMC Bioinformatics | Full text | Dinucleotide controlled null models for comparative RNA Gene Prediction

11 June 2012 Researchers at the Babraham Institute have identified a molecule that regulates the growth of the placenta during pregnancy. The findings, published this week in ‘Nature Cell Biology’, have important implications for understanding a healthy pregnancy.

New research provides insight into placental growth and healthy pregnancy

http://www.wellcome.ac.uk/News/2012/News/WTVM055430.htm