Literature & Protocols
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Several thousand human genes, amounting to aboutone-third of the whole genome, are potential targetsfor regulation by the several hundred microRNAs(miRNAs) encoded in the genome. The regulationoccurs posttranscriptionally and involves the ~21-nucleotide miRNAinteracting with a target site in themRNAthat generally has imperfect complementarityto the miRNA. The target sites are almost invariablyin the 3′-untranslated region of the messenger RNA(mRNA), often in multiple copies.
micro RNA and qRT-PCR
Welcome to the online edition of the Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics . Edited by Lynn Jorde , Peter Little , Mike Dunn and Shankar Subramaniam , this is a fantastic resource that brings together for the first time all four fields of genetics, genomics, proteomics and bioinformatics in an online format for faster delivery of content to meet your dynamic research requirements. The Browse by Contents button above takes you to the full table of contents. The articles are also classified by type, as Introductory Reviews for people new to a subject, Specialist Reviews that provide in-depth coverage for those with more experience, Short Specialist reviews that address cutting-edge topics in current research, and Basic Techniques essays or Tutorials.