DNA

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Welcome to the DNA branch of our Pearltree! DNA is the molecule responsible for life. In this branch, you will find resources describing what DNA looks like, where it is found, how it is made, and how we can use it to study the past as well as help our future. You will also find a virtual lab and a link to a museum with a DNA exhibit. Happy Learning! Feb 22

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A Scientific Breakthrough The sentence "This structure has novel features which are of considerable biological interest" may be one of science's most famous understatements. It appeared in April 1953 in the scientific paper where James Watson and Francis Crick presented the structure of the DNA-helix, the molecule that carries genetic information from one generation to the other. Nine years later, in 1962, they shared the Nobel Prize in Physiology or Medicine with Maurice Wilkins, for solving one of the most important of all biological riddles. Half a century later, important new implications of this contribution to science are still coming to light. What is DNA?

How DNA Was Discovered

http://www.nobelprize.org/educational/medicine/dna_double_helix/readmore.html
It’s remarkable what can happen when James Watson isn’t in the room. The Nobel laureate, known for his brilliance as well as his large ego and small superego, was expected to participate in a panel discussion Tuesday night about the play " Photograph 51 ," which focuses on Rosalind Franklin and her x-ray diffraction work in the early 1950s at King’s College London that contributed to discoveries of the molecular structure of DNA, first published in 1953. Watson, Francis Crick and Maurice Wilkins received the Nobel Prize in medicine or physiology in 1962 for this work, four years after Franklin’s death of ovarian cancer, possibly induced by her work with x-rays. Nobels are only awarded to living scholars but a handful of researchers and advocates in the past few decades have argued that Franklin deserves more credit than she got for the DNA discovery. http://blogs.scientificamerican.com/observations/2010/11/03/rosalind-franklin-and-dna-how-wronged-was-she/

Was Rosalind Franklin Robbed?

Cracking the Code of Life PBS Airdate: April 17, 2001 ROBERT KRULWICH: When I look at this—and these are the three billion chemical letters, instructions for a human being—my eyes glaze over. But when scientist Eric Lander looks at this he sees stories. ERIC LANDER (Whitehead Institute/MIT) : The genome is a storybook that's been edited for a couple billion years.

Cracking the Code of Life Video

http://www.pbs.org/wgbh/nova/body/cracking-the-code-of-life.html
http://www.pbs.org/wgbh/nova/body/sequence-DNA-for-yourself.html Good Parents, Troubled Teens Miles O'Brien, producer of "Mind of a Rampage Killer," describes what it's like to meet the parents of troubled teens. How Do We Perceive Risk? Why mass murders and other tragedies that kill scores of people make us most fearful.

Sequence DNA Virtual Lab

http://www.genome.gov/12011238 An Overview of the Human Genome Project What was the Human Genome Project? The Human Genome Project (HGP) was the international, collaborative research program whose goal was the complete mapping and understanding of all the genes of human beings. All our genes together are known as our "genome." The HGP was the natural culmination of the history of genetics research.

An Overview of the Human Genome Project

Summary DNA structure: click on the image to see it rotate In this activity, students “discover” the structure of DNA by playing with puzzle pieces representing the component pieces of the DNA molecule: the sugar deoxyribose, phosphate groups, and the 4 nucleic acids (adenine, thymine, cytosine and guanine). The process the students go through in putting the puzzle together resembles the way James Watson and Francis Crick deduced the molecular structure of DNA by manipulating molecular models of the component pieces (and a heavy reliance on the prior experimental work of Rosalind Franklin, Maurice Wilkins, and Erwin Chargaff). The model created by the students makes a lovely classroom decoration and reference for discussing DNA replication, transcription and translation.

Building DNA Lab

http://www.mysciencebox.org/DNAmodels
http://www.pbs.org/wgbh/nova/body/journey-into-human-dna.html

NOVA | Journey Into Human DNA

Good Parents, Troubled Teens Miles O'Brien, producer of "Mind of a Rampage Killer," describes what it's like to meet the parents of troubled teens. How Do We Perceive Risk? Why mass murders and other tragedies that kill scores of people make us most fearful. Food Science: Expert Q&A Michael Brenner, who teaches a class on the science of cooking, talks about egg whites, ethylene, protein, and more.

DNA Testing Completes Picture of king Tut

http://www.goupstate.com/article/20100216/ARTICLES/100219723 Two years of DNA testing and CT scans on Tut's 3,300-year-old mummy and 15 others are helping end many of the myths surrounding the boy king. While a comparatively minor ruler, he has captivated the public since the 1922 discovery of his tomb, which was filled with a stunning array of jewels and artifacts, including a golden funeral mask. The study, which will be published Wednesday in the Journal of the American Medical Association, provides the firmest family tree yet for Tut. The tests pointed to Pharaoh Akhenaten, who tried to revolutionize ancient Egyptian religion to worship one god, as Tut's father. His mother was one of Akhenaten's sisters, it said.

King Tut Unwrapped : Videos

Although there is an annoying ad at the beginning, the video is excellent and full of information about the teasting of King Tut's DNA and the results. by lauradember Feb 17