The Control of the Cell Cycle. Scientists create human stem cells through cloning. Stem-cells-mouse-regenerative-medicine_n_3907965. By Kate Kelland LONDON (Reuters) - Scientists have succeeded in generating new stem cells in living mice and say their success opens up possibilities for the regeneration of damaged tissue in people with conditions ranging from heart failure to spinal cord injury. The researchers used the same "recipe" of growth-boosting ingredients normally used for making stem cells in a petri dish, but introduced them instead into living laboratory mice and found they were able to create so-called reprogrammed induced pluripotent stem cells (iPS cells).
"This opens up new possibilities in regenerative medicine," said Manuel Serrano, who led the study at the Spanish National Cancer Research Centre in Madrid. Stem cell experts who were not directly involved in the study said its success was exciting, but noted that the technique as it stands could not be used in humans since the reprogrammed cells also lead to tumors forming in the mice.
(Reporting by Kate Kelland, editing by Ralph Boulton) Team reportedly grows 'better quality' stem cells in live mice. Researchers have reprogrammed cells inside living mice -- and have discovered that the pluripotent stem cells created in the process are even more flexible than those derived from embryos or grown in laboratory dishes. Someday the achievement might help scientists devise ways to treat human disease by directly regenerating tissues within human patients, said Manuel Serrano, an investigator at the Spanish National Cancer Research Center in Madrid and senior author of a study (abstract here) detailing the research, published online Wednesday by the journal Nature.
But that won't happen immediately, he added during a call with reporters Tuesday. The pluripotent stem cells are highly flexible and have the potential to develop into nearly any cell type in the body. Interest in stem cells pushed scientists first to figure out ways to isolate them from embryos and then to rewind mature cells into a more flexible state. That, in itself, was new. "That would be a major surprise," they said.
Human Stem Cell Banks in the US Market Research. Scientists create human liver from stem cells. UPDATE 1-Scientists grow mini human brains from stem cells. Artificial blood vessels grown from stem cells. World's First £250,000 Stem Cell Burger to be Served in London Next Week. Next week, someone at a yet undisclosed location in London will get to eat the most expensive burger ever made – which cost a whopping £250,000! We’re talking about the world’s first lab-grown burger, which is made from 20,000 strips of cultured meat grown from cow’s stem cells. Combined with lab-grown fat, the burger is said to look and taste like the real thing – except no cows had to die to make it. Image via Shutterstock Funded in part by the Dutch government and an anonymous $396,000 donation, Mark Post’s research at the University of Maastricht in the Netherlands is aimed at developing solutions to a burgeoning demand for meat.
The World Health Organization has warned that in the next four decades, meat demand will double, but current production methods are not only unsustainable environmentally, given the amount of methane released by cows, but also involve serious animal welfare violations. “The whole presentation next week will be a proof of concept,” Post said. Via KDVR. German cardiologist’s stem-cell papers attacked. The copious publications of high-profile German cardiologist Bodo-Eckehard Strauer — who has long claimed that stem cells derived from bone-marrow cells can repair damage in diseased hearts — have come under new attack. Strauer, who retired from the University of Düsseldorf in 2009, has been a controversial figure in Germany since he first claimed clinical success with the approach in 2001. Many stem-cell scientists have been openly sceptical of his claims, which have been reported enthusiastically in the media. An article published this week in the International Journal of Cardiology dissects 48 of the papers from his group and exposes a series of problems, including arithmetic errors in the presentation of statistics and identical results in papers presenting different numbers of patients.
The authors also searched systematically in all of the papers for discrepant information — pairs of statements that could not both be true. They document hundreds of errors.