Experience Vaults: Psychedelics information. Drug Music - Stereodose Radio. Medications That Increase Serotonin Levels. Serotonin functions as a chemical messenger in the brain. It regulates mood, sleep, appetite and the emotional perception of pain. Medications that increase serotonin levels are used primarily to alleviate the symptoms associated with moderate to severe depression, including low affect and loss of pleasure in previously enjoyed activities.
Newer antidepressants, known as selective serotonin reuptake inhibitors (SSRIs), elevate serotonin by blocking the chemical's recycling and inactivation. However, cells in the brain will also synthesize more serotonin under conditions where they have abundant access to the amino acid L-tryptophan and to 5-hydroxytryptophan. SSRIs, developed by pharmaceutical companies such as Eli Lilly (Prozac, fluoxetine), Pfizer (Zoloft, sertraline) and GlaxoSmithKline (Paxil, paroxetine), effectively manage depressive episodes in the majority of outpatients. Disregard Everything I Say - The Potential Negative Effects of MDMA and How to Counteract Them.
I recently added a comprehensive health effects, potential addiction, and tolerance as well as a legal issues section to everyone of my specific substance guides. I wanted to add this article to specifically include with the MDMA health section; since there was so much information and preventative tips, it was necessary to make it an article on its own.
This was so all the information was in one simple place, so people no longer have to trawl through random forum posts. Once again, this article is not written by me, but the same friend of mine who wrote the previous article on “An Explanation of the Effect of Hallucinogens upon the Nervous System”. Negative Effects on HealthSerotonin syndrome occurs when there is an excess of serotonergic activity in the central nervous system (CNS). Serotonin syndrome can often be overcome by resting in a cooler environment. Autonomic Neuromotor Twitching, restlessness, tremor, in-coordination rigidity, teeth chattering, reduced opening of jaw, seizures. Erowid. DanceSafe.Org: Drug Information and Harm Reduction Resources | DanceSafe.Org. How do u make MDMA.
It's not simple, even though it is considered "simple" from an organic chemical synthesis point of view. Nor is the information in any way secret or illegal to know or understand. Of course, it's completely illegal to actually do, and likely to get you arrested, plus full of ways you could horribly injure yourself with thermal burns, chemical burns, explosions, and poisonous fumes. So, in the interest of scientific freedom, here's a simple overview. If you want to actually understand it, go take some organic chemistry classes! You start with a cool mixture of 30% hydrogen peroxide in water and 80% formic acid in water. Dissolve the residue in methanol treated with 15% sulfuric acid, heat for three hours in a steam bath, refluxing the methanol.
Extract the result three times using standard polar/nonpolar solvent extraction techinques. You may want to do a distillation to purify this. Add the purified 3,4-methylenedioxyphenylacetone to about twice the mass of N-methylformamide. Bright Star's MDMA Synthesis for the First Time Chemist - [www.rhodium.ws] Introduction Thanks to Strike, Rhodium, Ritter, Osmium, r2d3, Semtex Enigma, Spiceboy, ChemHack, Labrat, Eleusis, Ketone/LabGrrrl, and a personal hero, Dr. Shulgin. And to the object that made this possible - the Internet. Disclaimer: This is for theoretical argument only. IF someone chooses to follow this synthesis, note that the product has been 'Scheduled 1' by the United States Government, and offenders can be prosecuted.
In no way do I condone this activity. This is a hypothetical synthesis for: 3,4-methylenedioxy-N-methylamphetamine. Overview: Distillation: of Natural Oil to obtain pure SafroleRxn: Formaldehyde + Ammonium Chloride -> MethylAmine.HCl (MeAm.HCl)Rxn: Safrole -(Wacker Oxidation(PdCl2+Benzoquinone))-> MDP2PDistillation: of Reaction contents to yield pure MDP2PRxn: MDP2P -(Al/Hg Amalgam (MeAm.HCl) -> MDMA oilCrystallization: (MDMA oil + HCl in IPA/Xylene) (anhydrous conditions) What you need: This list is the basics.
Apparatus and Glass: Chemicals: Step 1. (4 hours) 1. 2. 3.