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For the past two months or so, I’ve been slowly migrating my scientific workflow (that’s a fancy way of saying “my chaotic data hacking”) from Matlab ((R) (TM) (C)) to Python . The results are overwhelmingly positive, so I’d like to rant about it a bit. First, some background. My work typically involves the analysis of tons of remote sensing observations contained in files of various formats ( netCDF if I’m very lucky, HDF if I’m lucky, some weird non-standard binary thing if I’m not); all these files span terabytes and terabytes of hard drive space stored in racks in a big temperature-controlled room somewhere high in the sky. I ssh to a central server on which all these drives are mounted; I then usually run there code in whatever language is the most convenient to analyze the data.