New Horizons: Mission to Pluto and the Kuiper Belt. New Horizons. Launched directly into an Earth-and-solar-escape trajectory with an Earth-relative velocity of about 16.26 km/s (58,536 km/h; 36,373 mph) it set the record for the highest velocity of a human-made object from Earth.
Using a combination of monopropellant and gravity assist, it flew by the orbit of Mars on 7 April 2006, Jupiter on 28 February 2007, the orbit of Saturn on 8 June 2008; and the orbit of Uranus on 18 March 2011. Its secondary mission is to fly by one or more other Kuiper belt objects (should a suitable target be available), and then the heliosphere. New Horizons Web Site.