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Psychopharmacology

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Salvia divinorum - Drugs Forum. Australia Australia was the first country to prohibit Salvia divinorum and salvinorin A. The committee responsible for the ban has admitted that there is "no evidence of a major public health hazard. " The ban went into effect June 1, 2002. Belgium On October 18, 2004 the Belgian government added salvinorin A to their list of controlled substances and took effect November 18, 2004. Brazil In 2005, Brazilian Customs began enforcing a regulation that prohibits importation of plant products without a permit. Canada In a December 2005 report the Marketed Health Products Directorate, an arm of Health Canada, recommended that Salvia divinorum be placed under the Controlled Drugs and Substances Act. Chile On August 8, 2007, the Chilean government issued a decree making the trafficking of Salvia divinorum and salvinorin A illegal.

Croatia On April 4, 2008, Salvia divinorum was added to Croatia’s list of controlled substances. Denmark Estonia Finland France Germany Iceland Italy Japan Latvia Lithuania Norway Poland. A Comprehensive Guide to Cooking Meth on ‘Breaking Bad’ Frank Ockenfels/AMC. Disclaimer: Cooking and/or selling methamphetamine and other controlled substances is illegal unless you are working under the aegis of a pharmaceutical company. As a chemist and someone interested in psychoactive drugs, I’m frequently asked if I watch the AMC series Breaking Bad and if the show accurately portrays clandestine chemistry. I am a huge fan of the show and frequently watch it while working in the lab late at night. Although the clandestine chemistry always appeared accurate at first glance, I desired a more detailed critique of Walter White’s syntheses.

But season after season my thirst for technical analysis was left unquenched; I found a few articles that touched on the clandestine chemistry, but none were comprehensive. After dedicating the last seven years of my life to organic chemistry, it felt like a natural departure from writing my dissertation to examine this matter more closely.

Nagai Nagayoshi(1844-1929) Pseudoephedrine. Methylamine. Sources. The Big & Dandy HBWR/MGS/LSA Thread - Second Iteration - Page 2. Interview with Alexander Shulgin. By DENNIS ROMERO LAFAYETTE, Calif. -- Perhaps it was a sign of things to come when a seven-story Monterrey Pine came crashing down on the property of old Alexander T. Shulgin--Sasha, they call him--missing his musty cobweb-entangled drug lab by inches. It could have been a good sign because the cantankerous 70-year-old wasn't around the back-yard workshop conducting one of his legendary experiments, which have been known to involve him downing any number of the new psychedelic drugs he invents in the name of science.

Imagine losing your mind on some unknown compound with unknown powers (some of this stuff makes LSD look like Vitamin D)--and a tree the length of three buses rocks your world to Richter proportions. The aliens have arrived! Maybe, though, it was a sign of nefarious things to come. To tell the truth, Sasha Shulgin doesn't much care anymore what the government thinks. He's tippy-toed around the law and the lawmen for long enough--30 years now. A Conversation with Terence Mckenna and Alexander (Sasha) Shulgin 1993. How do you smoke DMT? A Mushroom That Speaks. How to grow magic mushrooms. How Magic Mushrooms Alter Your Brain | disinformationdisinformation. Groundbreaking Geniuses And The Drugs They Say Inspired Them.

The Ibogaine Story. "I have seen the best minds of my genertion, starving, hysterical, naked, Dragging themselves through negro streets at dawn, looking for an angry fix... " --Allen Ginsberg, the opening lines, HOWL; 1954 "What we're looking for is something wecan spray over theSoviet trenches, and they'll march out whistling 'Yankee Doodle Dandy'.

" -- Ascribed to a CIA advisor, Defense Department, Pharmaco-Warfare Division "Thus Spake Zarathrustra: 'Praise Be to Haoma! '" -- Yasna #3 The Ibogaine Story:Report on the STATEN ISLAND PROJECT Table of Contents Exhibits: HOWL Introduction (above) Introduction, NAKED LUNCH SOHO NEWS Heroin Poster Isbell letter (page one) ~ (page two) CIA Funding of Isbell's Research, 1953-61. I. II. III. Search The Text of The Book For Key Words From the Introduction, NAKED LUNCH DEPOSITION: TESTIMONY CONCERNING A SICKNESS The Sickness is drug addiction and I was an addict for fifteen years. I have seen the exact manner in which the junk virus operates through fifteen years of addiction. BBC Horizon: Psychedelic Science - (DMT, LSD, Ibogaine) Ayahuasca. Ayahuasca (UK: /ˌaɪ(j)əˈwæskə/, US: /-ˈwɑːskə/) or ayaguasca[1] (in Hispanicized spellings) from Quechua Ayawaska[2] (aya: soul, waska: vine), or yagé (/jɑːˈheɪ, jæ-/), is an entheogenic brew made out of Banisteriopsis caapi vine and other ingredients.[3] The brew is used as a traditional spiritual medicine in ceremonies among the indigenous peoples of the Amazon basin and is known by a number of different names (see below).[4] B. caapi contains several alkaloids that act as monoamine oxidase inhibitors (MAOIs).

Another common ingredient in ayahuasca is the shrub Psychotria viridis which contains the primary psychoactive, dimethyltryptamine (DMT). MAOIs are required for DMT to be orally active.[5] Nomenclature[edit] Ayahuasca is known by many names throughout Northern South America and Brazil. Ayahuasca is the hispanicized spelling of a word in the Quechua languages, which are spoken in the Andean states of Ecuador, Bolivia, Peru, and Colombia. History[edit] Preparation[edit] DMT admixtures: The Ayahuasca Experience. Ibogaine. Ibogaine is a naturally occurring psychoactive substance found in plants in the Apocynaceae family such as Tabernanthe iboga, Voacanga africana and Tabernaemontana undulata.

A psychedelic with dissociative properties, the substance is banned in some countries; in other countries it is used by proponents of psychedelic therapy to treat addiction to methadone, heroin, alcohol, cocaine, methamphetamine, anabolic steroids, and other drugs. Ibogaine is also used to treat depression and post traumatic stress disorder.

Derivatives of ibogaine that lack the substance's psychedelic properties are under development.[1] Ibogaine-containing preparations are used for medicinal and ritual purposes within African spiritual traditions of the Bwiti, who claim to have learned it from the Pygmy peoples. Although it was first commonly advertised as having anti-addictive properties in 1962 by Howard Lotsof, its western use predates that by at least a century. History[edit] Synthesis[edit] Psychotherapy[edit] Manual for Ibogaine Therapy. "Regarding the manual I would disagree with some of the exclusion criteria," says one author. "By excluding patients that are depressed or bipolar you exclude a sizable portion of the addict population.

Because ibogaine's metabolites have been shown to have an antidepressant effect it would probably help these patients. Proper treatment for psychiatric conditions can be administered afterward. You will find below some of the experience we have had with patients taking antidepressants prior to ibogaine and since many patients have psychiatric conditions, we don't consider it prudent or necessary to suspend psychotropics for longer than 24 hours before treatment. Below are presented three examples of such patients. All of these patients suspended their medications 24 hours prior to treatment and apparently had no different responses to ibogaine or any unexpected side effects. " "Since most patients are depressed, a fast acting antidepressant can help in the days after ibogaine. 1. 2. 3. By. Scopolamine: Powerful drug growing in the forests of Colombia that ELIMINATES free will. Scopolamine often blown into faces of victims or added to drinksWithin minutes, victims are like 'zombies' - coherent, but with no free willSome victims report emptying bank accounts to robbers or helping them pillage own houseDrug is made from borrachero tree, which is common in Colombia By Beth Stebner Published: 22:44 GMT, 12 May 2012 | Updated: 13:43 GMT, 13 May 2012 A hazardous drug that eliminates free will and can wipe the memory of its victims is currently being dealt on the streets of Colombia.

The drug is called scopolamine, but is colloquially known as ‘The Devil’s Breath,' and is derived from a particular type of tree common to South America. Stories surrounding the drug are the stuff of urban legends, with some telling horror stories of how people were raped, forced to empty their bank accounts, and even coerced into giving up an organ. Scroll down for video Danger: 'The Devil's Breath' is such a powerful drug that it can remove the capacity for free will. A Brief History of the San Pedro Cactus. The Book That Can't Be Read.

New signs of language surface in mystery Voynich text - physics-math - 21 June 2013. Read full article Continue reading page |1|2 A mysterious and beautiful 15th-century text that some researchers have recently deemed to be gibberish may not be a hoax after all. A new study suggests the text shares quantifiable features with genuine language, and so may contain a coded message.

That verdict emerges from a statistical technique that puts a figure on the information content of elements in a text or code, even if their meaning is unknown. The Voynich manuscript has baffled and captivated researchers since book dealer Wilfred Voynich found it in an Italian monastery in 1912. Although the patterns of word lengths and symbol combinations in the text are similar to those in real languages, several recent studies have suggested that the book was a clever 15th-century hoax designed to dupe Renaissance book collectors, and that the words have no meaning. Word entropy Their results support the idea that Voynich text really does contain a secret message. Relatedness score Word clusters. The Mush Room | About Us. The-mush-room.co.uk is a one stop shop for mushroom enthusiasts and ethnobotanical plant lovers. Ethnobotany (from "ethnology" - study of culture and "botany" - study of plants) is the scientific study of the relationships that exist between people and plants.

We stock active mushroom spores and edible and novelty live cultures. You will also find psycoactive plants and seeds from all around the world. All our plants are grown organically, most from our own seed, here in the Cornish sunshine. We are always adding new and interesting products, therefore our stock list is constantly being updated. If you are looking for a specific plant, seed or strain that we do not carry, please contact us and we will find it for you! We also run a 'Trading post'.

Live salvia plants. Erowid. Psychopharmacology. Czechkyle. Psychopharmacology. An arrangement of psychoactive drugs The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain. Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as "drug action", and the widespread changes in physiological or psychological function is referred to as "drug effect".

These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory. Historical overview[edit] Early psychopharmacology[edit] The common muscimol-bearing mushroom Amanita muscaria, also known as the "Fly Agaric" Modern psychopharmacology[edit] Chemical signaling[edit] Neurotransmitters[edit] Hormones[edit] Psychopharmacological substances[edit] Alexander Shulgin. Alexander "Sasha" Theodore Shulgin[2] (born June 17, 1925) is an American medicinal chemist, biochemist, pharmacologist, psychopharmacologist, and author. Shulgin is credited with introducing MDMA ("ecstasy") to psychologists in the late 1970s for psychopharmaceutical use.

He discovered, synthesized, and personally bioassayed over 230 psychoactive compounds, and evaluated them for their psychedelic and/or entactogenic potential. Due in part to Shulgin's extensive work in the field of psychedelic research and the rational drug design of psychedelic drugs, he has since been dubbed the "godfather of psychedelics".[3] Life and career[edit] Shulgin was born in Berkeley, California to Theodore Stevens Shulgin (1893–1978)[4] and Henrietta D. (née Aten) Shulgin (1888–1960).[5][6] His father was born in Russia, while his mother was born in Illinois. Shulgin began studying organic chemistry as a Harvard University scholarship student at the age of 16. He lives in Lafayette, California. Books[edit] Dimethyltryptamine.

History[edit] Another historical milestone is the discovery of DMT in plants frequently used by Amazonian natives as additive to the vine Banisteriopsis caapi to make ayahuasca decoctions. Biosynthesis[edit] Biosynthetic pathway for N,N-dimethyltryptamine This transmethylation mechanism has been repeatedly and consistently proven by radiolabeling of SAM methyl group with carbon-14 (14C-CH3)SAM).[22][20][24][25][26] Evidence in mammals[edit] In 2013, researchers first reported DMT in the pineal gland microdialysate of rodents.[28] A study published in 2014 reported the biosynthesis of N,N-dimethyltryptamine (DMT) in the human melanoma cell line SK-Mel-147 including details on its metabolism by peroxidases. [29] In a 2014 paper, a group first demonstrated the immunomodulatory potential of DMT and 5-MeO-DMT through the Sigma-1_receptor of human immune cells. INMT[edit] Endogenous DMT[edit] The first claimed detection of mammalian endogenous DMT was published in June 1965: German researchers F.

Psilocybin. Psilocybin[nb 1] (/ˌsɪləˈsaɪbɪn/ SIL-ə-SY-bin) is a naturally occurring psychedelic compound produced by more than 200 species of mushrooms, collectively known as psilocybin mushrooms. The most potent are members of the genus Psilocybe, such as P. azurescens, P. semilanceata, and P. cyanescens, but psilocybin has also been isolated from about a dozen other genera. As a prodrug, psilocybin is quickly converted by the body to psilocin, which has mind-altering effects similar (in some aspects) to those of LSD, mescaline, and DMT. In general, the effects include euphoria, visual and mental hallucinations, changes in perception, a distorted sense of time, and spiritual experiences, and can include possible adverse reactions such as nausea and panic attacks. History[edit] Early[edit] Modern[edit] Albert Hofmann (shown here in 1993) purified psilocybin and psilocin from Psilocybe mexicana in the late 1950s. Occurrence[edit] Mescaline.

Mescaline or 3,4,5-trimethoxyphenethylamine is a naturally occurring psychedelic alkaloid of the phenethylamine class, known for its hallucinogenic effects similar to those of LSD and psilocybin. It shares strong structural similarities with the catecholamine dopamine. It occurs naturally in the peyote cactus (Lophophora williamsii),[1] the San Pedro cactus[2] (Echinopsis pachanoi) and in the Peruvian torch (Echinopsis peruviana), and as well in a number of other members of the Cactaceae plant family.

It is also found in small amounts in certain members of the Fabaceae (bean) family, including Acacia berlandieri.[3] Naturally derived mescaline powder extract. History and usage[edit] Peyote has been used for at least 5700 years by Native Americans in Mexico.[4] Europeans noted use of peyote in Native American religious ceremonies upon early contact, notably by the Huichols in Mexico. Potential medical usage[edit] Notable users[edit] Biosynthesis of mescaline[edit] Synthetic Mescaline[edit]

Sacred Peyote. Peyote: I Wish We All Could Be Members of the Native American Church. St John's wort. High As A Kite. Drugs.