FACES OF FIBRO Milnacipran Milnacipran (Ixel, Savella, Dalcipran, Toledomin) is a serotonin–norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia. It is not approved for the clinical treatment of major depressive disorder in the USA, but it is in other countries. Medical uses[edit] Depression[edit] In a pooled analysis of 7 comparative trials with imipramine,[1] milnacipran and imipramine were shown to have comparable efficacy while milnacipran was significantly better tolerated. Fibromyalgia[edit] During its development for fibromyalgia, milnacipran was evaluated utilizing a composite responder approach. Side effects[edit] The most frequently occurring adverse reactions (≥ 5% and greater than placebo) were nausea, headache, constipation, dizziness, insomnia, hot flush, hyperhidrosis, vomiting, palpitations, heart rate increase, dry mouth, and hypertension [FDA Savella prescribing information]. Interactions[edit] Contraindications[edit] Pharmacology[edit] Pharmacokinetics[edit]
Ashwagandha: What You Need to Know about the Powerful Anti-Stress, High Energy Plant (Also Known as Indian Ginseng) Do you feel stressed out, anxious, or need some rejuvenation? Then you should consider supplementing with Ashwagandha! Do you want to feel more relaxed, have more energy, and enjoy a vibrant relationship? Then you should try Ashwagandha. Ashwagandha, also known as Indian Ginseng, comes from a shrub that grows in India, Pakistan and Sri Lanka. The plant's roots, leaves and berries have been used for years in Ayurvedic treatments, and legend has it that the Romans even added it to their wine for its beneficial effects. Now, scientific studies are showing that this special herb has amazing medicinal properties too! Ashwagandha has been shown to be effective in these cases: Reduces anxietyActs as an antioxidantImproves brain functionHas antibacterial propertiesLowers cortisol levelsBoosts sexual vitality Antidote for the Modern Lifestyle Ashwagandha certainly has medical value, and it may be the cure for what ails us. But Ashwagandha has none of the side of effects of prescription antidepressants!
National Institutes of Health (NIH) - Home Page Ashwagandha Ashwagandha, one of the most vital herbs in Ayurvedic healing, has been used since ancient times for a wide variety of conditions, but is most well known for its restorative benefits. In Sanskrit ashwagandha means “the smell of a horse,” indicating that the herb imparts the vigor and strength of a stallion, and it has traditionally been prescribed to help people strengthen their immune system after an illness. In fact, it’s frequently referred to as “Indian ginseng” because of its rejuvenating properties (although botanically, ginseng and ashwagandha are unrelated). Belonging to the same family as the tomato, ashwagandha (or Withania somnifera in Latin) is a plump shrub with oval leaves and yellow flowers. Scientific Research Ashwagandha contains many useful medicinal chemicals, including withanolides, (steroidal lactones), alkaloids, choline, fatty acids, amino acids, and a variety of sugars. Practical Uses and Precautions The usual recommended dose is 600 to 1000 mg, twice daily.
Effect of Indian Ayurvedic Medicine Ashwagandha on Measurement of Serum Digoxin and 11 Commonly Monitored Drugs Using Immunoassays: Study of Protein Binding and Interaction With Digibind | Archives of Pathology & Laboratory Medicine | Find Articles at In Search of..... - TV.com www.tv.com/shows/in-search-of Narrarated by Leonard Nimoy, In search of was a 30 minute syndicated show that covered a wide range of paranormal topics. It pioneered a lot of the methodology that ... Search Engine - Download.com download.cnet.com/s/search-engine search engine free download - GSA Search Engine Ranker, Nomao - The personalized search engine, Zoom Search Engine, and many more programs Google Search - Download.com download.cnet.com/s/google-search google search free download - Google Search, Google Toolbar for Internet Explorer, Google Search, and many more programs Star Search - Episode Guide - TV.com www.tv.com/shows/star-search-2003/episodes Star Search episode guides on TV.com.
Fibromyalgia: A Disorder of the Brain? – Source: Neuroscientist, Feb 12, 2008 This article presents evidence that Fibromyalgia patients have alterations in CNS [central nervous system] anatomy, physiology, and chemistry that potentially contribute to the symptoms experienced by these patients. n There is substantial psychophysical evidence that Fibromyalgia patients perceive pain and other noxious stimuli differently than healthy individuals and that normal pain modulatory systems, such as diffuse noxious inhibitory control mechanisms, are compromised in Fibromyalgia. n Furthermore, functional brain imaging studies revealing enhanced pain-related activations corroborate the patients' reports of increased pain. n Neurotransmitter studies show that Fibromyalgia patients have abnormalities in dopaminergic, opioidergic, and serotoninergic systems. n Finally, studies of brain anatomy show structural differences between the brains of Fibromyalgia patients and healthy individuals.
Herbs for Depression, Weight Loss, Menopause, Diabetes, Insomnia, PMS, Anxiety... Print Friendly Ashwagandha, an exotic Indian herb, has remarkable stress-relieving properties comparable to those of powerful drugs used to treat depression and anxiety. In addition to its excellent protective effects on the nervous system, ashwagandha may be a promising alternative treatment for a variety of degenerative diseases such as Alzheimer’s and Parkinson’s. Ashwagandha has powerful antioxidant properties that seek and destroy the free radicals that have been implicated in aging and numerous disease states. Even more remarkable, emerging evidence suggests that ashwagandha has anti-cancer benefits as well. Powerful Protective Effects on the Nervous System Stress, environmental toxins, and poor nutrition all have a detrimental impact on our nervous systems. Scientific studies support ashwagandha’s ability not only to relieve stress, but also to protect brain cells against the deleterious effects of our modern lifestyles. Other studies of chronic stress support these findings. Conclusion
Drugs.com | Prescription Drug Information, Side Effects & Interactions Ashwagandha Fruits Withania somnifera, known commonly as ashwagandha,[2] Indian ginseng,[3] poison gooseberry,[3] or winter cherry,[2] is a plant in the Solanaceae or nightshade family. Several other species in the genus Withania are morphologically similar.[4] It is used as an herb in Ayurvedic medicine. Description[edit] This species is a short shrub growing 35 to 75 centimeters tall. Tomentose branches extend radially from a central stem. Etymology[edit] The species name somnifera means "sleep-inducing" in Latin.[5] Cultivation[edit] Withania somnifera is cultivated in many of the drier regions of India, such as Mandsaur District of Madhya Pradesh, Punjab, Sindh, Gujarat,and Rajasthan.[6] It is also found in Nepal.[7] Pathology[edit] Withania somnifera is prone to several pests and diseases. Culinary use[edit] The berries can be used as a substitute for rennet in cheesemaking.[6] Biochemistry[edit] The main chemical constituents are alkaloids and steroidal lactones. Traditional medicinal uses[edit]
Amruta Herbals Pvt. Ltd. Author: Dr. Ajay Padmawar A small or middle-sized under shrub, erect, greyish or hoary, branching, perennial about 30 cm to 1.5 m in height. Stem and branches covered with minute star-shaped hairs. * Rasa:: tikta, kashaya * Vipaka:: katu * Virya:: ushna * Karma:: Vatapittahara, Kaphakopa, balyam, vajikarana, tonic, adaptogen, relaxing nervine, post-partum tonic, immunomodulant, astringent, galactagogue, diuretic, thermogenic The principle constituents of its roots Compounds known as withanolides are believed to account for the multiple medicinal applications of ashwagandha.These molecules are steroidal lactones(highly oxygenated C-28 steroid derivatives) with erggostane, which (include withanone, withaferin, withanolides, withasomidienone, withanolide C and alkanoids about 0.2 %) and bear a resemblance, both in their action and appearance, to the active constituents of Asian ginseng (Panax ginseng) known as ginsenosides. None reported (Aphale et al 1998). .