Gene Designer Software and Demos - DNA2.0 The DNA design tool for today’s molecular biologists Capture your entire gene design process in one efficient application, using a range of design tools purposely built for the task: Intelligent, fast, and easy-to-use algorithms for in silico cloning, codon optimization, back translation and primer design. Gene Designer Sequence View enables easy manipulation of sequence elements, codon choices, and oligonucleotide positions. You Dream It. Assembling genetic building blocks using Gene Designer 2.0 enables you to design, clone and validate in powerful new ways. Codon optimize for recombinant protein expression in any organism using multiple codon-optimization algorithms. Gene Designer clones with drag-and-drop convenience. PLEASE NOTE: The gene design algorithm described in PLoS ONE 4(9):e7002 (Welch et al.,) is not incorporated into the Gene Designer software. The DNA design tool for tomorrow’s scientists Examples of Gene Designer 2.0 in Curricula and Student Projects: Ongoing Support
www.estagiar.pt | Informações sobre estágios EBI Tools: ClustalW Multiple Sequence Alignment (MSA) is generally the alignment of three or more biological sequences (protein or nucleic acid) of similar length. From the output, homology can be inferred and the evolutionary relationships between the sequences studied. By contrast, Pairwise Sequence Alignment tools are used to identify regions of similarity that may indicate functional, structural and/or evolutionary relationships between two biological sequences. Clustal Omega New MSA tool that uses seeded guide trees and HMM profile-profile techniques to generate alignments. Launch Clustal Omega Kalign Very fast MSA tool that concentrates on local regions. Launch Kalign MSA tool that uses Fast Fourier Transforms. Launch MAFFT Accurate MSA tool, especially good with proteins. Launch MUSCLE MView Transform a Sequence Similarity Search result into a Multiple Sequence Alignment or reformat a Multiple Sequence Alignment using the MView program. Launch MView T-Coffee Launch T-Coffee WebPRANK
DNAWorks at Helix Systems DNAWorks (v3.2.2) The availability of sequences of entire genomes has dramatically increased the number of protein targets, many of which will need to be overexpressed in cells other than the original source of DNA. Gene synthesis often provides a fast and economically efficient approach. The synthetic gene can be optimized for expression and constructed for easy mutational manipulation without regard to the parent genome. Yet design and construction of synthetic genes, especially those coding for large proteins, can be a slow, difficult and confusing process. DNAWorks automates the design of oligonucleotides for gene synthesis by PCR-based methods. A description of the original DNAWorks can be found in our publication (Hoover, D. and Lubkowski, J., 2002). For further improvements in the performance of DNAWorks, feedback on the success or failure of gene synthesis using DNAWorks is very important.
e-escola | Instituto Superior Técnico Sci-Ed Software - Products Clone Manager Basic acts as an expert system to help with cloning simulation, enzyme operations and graphic map drawing. You can also use Clone Manager as a quick and easy way to view or edit sequence files, find open reading frames, translate genes, or find genes or text in files. Use Enzymes, Simulate Cloning Find enzyme sites, view enzyme info Do restriction enzyme analysis Updated enzyme list display Cut, ligate DNA, modify molecule ends Plan Cloning, Gateway, Topo Cloning Wizards Draw Graphic Maps Prepare high-resolution graphic maps Print, copy to clipboard, export to file Enhanced Views of graphic map Other Features Integrated sequence editor and file handler Extensive sequence formatting options Updated, built-in DataBook database Analysis Functions Open Reading Frame analysis DNA, protein analysis functions Mutagenesis Profile module More information: New in Clone Manager Basic 9 Detailed Program Description (pdf) Ordering information License Type information Faxable Order Form
Natural Sciences Repository AMAbiotics The company AMAbiotics is a research and service company focused on the link between microbial metabolism, nutrition and health. Using cutting-edge techniques in genomics and modelling, AMAbiotics develops for its own account or with partners a portfolio of know-how, patents and applications. In brief Living beings make communities where each has its own place, from indifference to collaboration, competition and even agression. Collaborations AMAbiotics is hosted at the Genopole Ile de France and it collaborates with the University of Evry. BioResearch Online:Sourcing for BioPharm Manufacturing, BioResearch Production, Contract Manufacturing