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CERTIFICATE OF MEDICAL NECESSITY ADDENDUM FOR PROVIGIL (MODAFINI To: Re: Treatment: Reference is made to the Certificate of Medical Necessity. Please be advised the patient has been prescribed modafinil. Modafinil is the first medication in a new class of medications with a unique mechanism of action, categorized as tuberomammillary activators. Narcolepsy is a chronic neurological disorder characterized by excessive daytime sleepiness. Current approaches to the management of narcolepsy combine pharmacological and behavioral therapies. PROVIGIL is the first non-amphetamine drug in 40 years to improve wakefulness in patients with excessive daytime sleepiness associated with narcolepsy. Idiopathic hypersomnia is a diagnosis applied to patients who are excessively sleepy and sleep for long periods of time without feeling refreshed. [1] It is also referred to as non-REM narcolepsy or CNS hypersomnia. [3] The etiology of EDS is patients with IH is unknown. [3] Rationale for Recommending PROVIGIL Therapy 1. : Diagnostic aspects of narcolepsy. 2. 3. 4. 5. 6. 7.

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