Les développements de l’immunologie Qui n’a pas constaté cette augmentation des phénomènes allergiques tels que l’eczéma, les rhinites, l’asthme et plus encore le développement des maladies auto-immunes dans lesquels bizarrement des agents destructeurs se tournent contre les propres cellules de l’individu et produisent des maladies comme : le lupus, la sclérose en plaques ou encore le diabète. Comprendre ces mécanismes intimes c’est l’enjeu du professeur David Klatzmann , professeur d’immunologie, qui démontre l’importance des cellules comme les lymphocytes dont l’équilibre ou le déséquilibre peut entraîner une bascule. Autre thématique : les fausses couches à répétition qui montre une diminution de la tolérance immunitaire classique et souhaitable au cours de la grossesse puisqu’elle permet de ne pas rejeter un hôte cellulaire pourtant étranger puisqu’il provient toujours d’un humain masculin.
MIT SENSEable City Lab Libre Accès à l'info scientifique et technique Publié le 26 avril 2017, par Thérèse HAMEAU Différents répertoires et moteurs sont à la disposition des internautes pour trouver des informations à propos du Libre Accès ou rechercher des documents librement accessibles. Ils sont classés selon quatre thématiques : politiques ou mandats des agences de financement ou des organismes de recherche / universités ; politiques des éditeurs ; revues en libre accès - voie dorée ; archives ouvertes - voie verte . 1. Quatre sites mettent à disposition un répertoire des politiques : 2. Plusieurs sites répertorient la politique des éditeurs vis-à-vis du dépôt, sur le web ou dans des archives ouvertes, des articles publiés dans leurs revues. Sherpa/Romeo (éditeurs internationaux, allemands, britanniques, canadiens, espagnols, hongrois, néerlandais, norvégiens, portugais) ; Héloïse (éditeurs français) ; Dulcinea (éditeurs espagnols) ; OAKList Database (éditeurs australiens) ; Diadorim (éditeurs brésiliens). 3. Répertoires de revues Le site HowOpenIsIt ? 4.
Scientists engineer animals with ancient genes to test causes of evolution – Science Life Kristi Montooth at the University of Nebraska holds a bottle with fruit flies, the subject of a new study on the genetic basis of adaptation and evolution. (Photo: University of Nebraska) Scientists at the University of Chicago have created the first genetically modified animals containing reconstructed ancient genes, which they used to test the evolutionary effects of genetic changes that happened in the deep past on the animals’ biology and fitness. The research, published early online in Nature Ecology & Evolution on Jan. 13, is a major step forward for efforts to study the genetic basis of adaptation and evolution. “We realized we could overcome this problem by combining two recently developed methods—statistical reconstruction of ancient gene sequences and engineering of transgenic animals,” he said. Kristi Montooth, from the University of Nebraska, and Mohammad Siddiq, from UChicago (Photo: University of Nebraska) Joe Thornton, PhD Like this: Like Loading... Related In "cell biology"
Coronavirus mutations and vaccines – worse than murder hornets I am skeptical of the wild claims about getting a COVID-19 vaccine in 12-18 months, and now there is powerful research about coronavirus mutations that makes me very concerned about getting an effective vaccine. And you thought murder hornets were bad? These coronavirus mutations could mean a disaster for current vaccine research – if we’re developing vaccines for a previous strain of COVID-19, rather than more current (and apparently, more virulent) coronavirus vaccines. This makes the murder hornets look like a ladybug. A recent paper looks at a particularly dangerous strain of coronavirus mutations that should make us reassess any optimism about getting a new COVID-19 vaccine. Coronavirus mutations study Because of the urgency to get coronavirus research out for researchers, many papers are being published online as “preprints,” while they are being peer-reviewed by major journals. Dr. Dr. What this means for vaccines And remember, this is just the first mutation. Notes Citations Related
Bioproduction de protéines thérapeutiques - Revue et perspectives Med Sci (Paris) 2009 ; 25 : 18–26 Bioproduction de protéines thérapeutiques Revue et perspectives Bioproduction of pharmaceutical proteins: review and perspectives Joëlle Dumas* et Bénédicte Robert* Genopole Campus 1, 5, rue Henri Desbruères, 91030 Évry Cedex, France * benedicte.robert@genopole.fr* joelle.dumas@genopole.fr Résumé La montée en puissance du marché biopharma- ceutique génère des besoins énormes en production de molécules thérapeutiques. Abstract The increase in importance of the biopharmaceutical market generates enormous needs in production of therapeutic molecules. © 2009 médecine/sciences - Inserm / SRMS Le contexte biopharmaceutique mondial Avec un marché biopharmaceutique en forte croissance, les besoins de production de molécules thérapeutiques sont grandissants. « Un pays développé doit pouvoir faire bénéficier sa population de ces nouvelles voies de traitement. La production de protéines thérapeutiques Tableau I. Applications médicales des protéines thérapeutiques. Tableau II.
Astrophysics Source Code Library Table of contents Oldest --> newest addition Making Access to Astronomical Software More EfficientAstronomical Software Wants To Be Free: A ManifestoPublish your computer code: it is good enoughTalking Amongst Ourselves - Communication in the Astronomical Software CommunityComputational science: ...Error …why scientific programming does not compute A Journal for the Astronomical Computing Community? The case for open computer programsAstroinformatics: A 21st Century Approach to AstronomyPublish or be damned? Shining Light into Black BoxesA Quick Guide to Software Licensing for the Scientist-ProgrammerTroubling Trends in Scientific Software UseOptimizing Peer Review of Software CodeCollaboration gets the most out of software The future of journal submissions (added 3/25/14)Reproducible Research in Computational Science (added 4/5/14)Science Code Manifesto (added 6/20/14)Reproducible research is still a challenge (added 6/21/14)Data Citation and Sharing: What’s in it for me? Authors: P.
MIT Press : Free Texts : Download & Streaming Includes bibliographical references Topics: Industries, Tools, Outils, Industrie, Civilization, Industries, Tools On The Definition of Word develops a consistent and coherent approach to central questions about morphology and its relation to syntax. In sorting out the various senses in which the word word is used, it asserts that three concepts which have often been identified with each other are in fact distinct and not coextensive: listemes (linguistic objects permanently stored by the speaker); morphological objects (objects whose shape can be characterized in morphological terms of affixation and... Topics: Word (Linguistics), Mot (Linguistique), Word (Linguistics), Woorden, Morfologie (taalkunde),... The Brooklyn Bridge and the Erie Canal are well-known feats of American civil engineering. "Includes 88 sound examples that are discussed in Current directions in computer music research edited by Max V. Daisy Books for the Print Disabled texts eye favorite 0 comment 0 W. favorite 1 MIT Press
Rýrnun jökla veldur aflögun þyngdarsviðs jarðar | Háskóli Íslands Ný rannsókn Dönsku geimferðastofnunarinnar (DTU-Space) í samvinnu við Jarðvísindastofnun Háskólans og Veðurstofu Íslands sýnir að unnt er að mæla rýrnun íslenskra jökla síðustu ár með gervihnöttum. Hefðbundnar afkomumælingar sýna að íslenskir jöklar hafa hopað og þynnst jafnt og þétt frá árinu 1995 sem nemur um 10 rúmkílómetrum af ís á ári að meðaltali. Þessi rýrnun jöklanna veldur aflögun þyngdarsviðs jarðar nærri Íslandi. Alexander Jarosch, fræðimaður í jöklafræði við Jarðvísindastofnun Háskólans, segir að niðurstaða rannsóknanna sé í samræmi við fyrirliggjandi afkomumælingar sem sýni að íslensku jöklarnir hafi samtals rýrnað um meira en 200 rúmkílómetra frá árinu 1995. Hlýnandi loftslag hefur haft mikil áhrif á stærstu jökla jarðar „Sökum þess að nýju mælingarnar sýna með beinum hætti breytingar á massa jöklanna má segja að íslensku jöklarnir hafi verið vigtaðir úr geimnum með þessum mælingum,“ segir Alexander.