Comparative Mammalian Brain Collections - StumbleUpon NeLM - National electronic Library for Medicines Careplans.com: Developed by nurses for nurses for care planning Cranial Nerves - StumbleUpon Can't remember the names of the cranial nerves? Here is a handy-dandy mnemonic for you: On Old Olympus Towering Top AFamous Vocal German Viewed Some Hops. The bold letters stand for: olfactory, optic, oculomotor, trochlear, trigeminal, abducens, facial, vestibulocochlear, glossopharyngeal, vagus, spinal accessory, hypoglossal. Still can't remember the cranial nerves? Master Muscle List Home Page Drugs.com | Prescription Drug Information, Interactions & Side Effects Khan Academy Tay-Sachs Disease Information Page: National Institute of Neurological Disorders and Stroke (NINDS) What is Tay-Sachs Disease? Tay-Sachs disease is a fatal genetic lipid storage disorder in which harmful quantities of a fatty substance called ganglioside GM2 build up in tissues and nerve cells in the brain. The condition is caused by insufficient activity of an enzyme called beta-hexosaminidase A that catalyzes the biodegradation of acidic fatty materials known as gangliosides. Gangliosides are made and biodegraded rapidly in early life as the brain develops. Infants with Tay-Sachs disease appear to develop normally for the first few months of life. Then, as nerve cells become distended with fatty material, a relentless deterioration of mental and physical abilities occurs. Is there any treatment? Presently there is no treatment for Tay-Sachs disease. What is the prognosis? Even with the best of care, children with Tay-Sachs disease usually die by age 4, from recurring infection. What research is being done? All NINDS-prepared information is in the public domain and may be freely copied.