About This page includes information about the aims and scope of BMC Bioinformatics, editorial policies, open access and article-processing charges, the peer review process and other information. For details of how to prepare and submit a manuscript through the online submission system, please see the instructions for authors. Scope BMC Bioinformatics is an open access, peer-reviewed journal that considers articles on all aspects of the development, testing and novel application of computational and statistical methods for the modeling and analysis of all kinds of biological data, as well as other areas of computational biology. BMC Bioinformatics is part of the BMC series which publishes subject-specific journals focused on the needs of individual research communities across all areas of biology and medicine. BMC series - open, inclusive and trusted. Editorial team Executive Editor Irene Pala Editorial Board Manager Paul Lambert Senior Managing Editor Diana Marshall Open access Indexing services e.g.
www.zo.utexas.edu/faculty/antisense/tree.pdf The Science of Dreams and Why We Have Nightmares by Maria Popova The psychology of our built-in nocturnal therapy. “The interpretation of dreams is the royal road to a knowledge of the unconscious activities of the mind,” Freud argued in his influential treatise The Interpretation of Dreams in 1900. In Dreamland: Adventures in the Strange Science of Sleep (public library) — best science books of 2012, exploring what happens while you sleep and how it affects your every waking moment, which also gave us this fascinating reads on sleep and the teenage brain — David K. Freud’s theories — premised on the idea that the symbolism of dreams encoded the dreamer’s subconscious desires and concerns, often of a sexual nature — were systematically challenged and dismissed over the course of the 20th century, but without much of a viable alternative theory. By the time [Hall] died in 1985, Hall had synopses of more than fifty thousand dreams from people of all age groups and nationalities. And yet theories continue to differ. Donating = Loving
Why some memories last and others fade We are more likely to form lasting memories when there is coordinated activity between two specific brain regions, MRI scans show. “When memories are supported by greater coordination between different parts of the brain, it’s a sign that they are going to last longer,” says Lila Davachi, an associate professor in the Department of Psychology and Center for Neural Science at New York University. It is commonly understood that the key to memory consolidation—the cementing of an experience or information in our brain—is signaling from the brain’s hippocampus across different cortical areas. Moreover, it has been hypothesized, but never proven, that the greater the distribution of signaling, the stronger the memory takes hold in our brain. To determine if there was scientific support for this theory, Davachi and a colleague examined how memories are formed at their earliest stages through a series of experiments over a three-day period. Source: NYU
Brain's Dumped DNA May Lead to Stress, Depression Humans and other mammals react to stressful situations through a series of well-orchestrated evolutionary adaptations. When faced with a predator looking for its next meal, or with worry of losing a job, our bodies release a cascade of stress hormones. Our heart rate spikes, breath quickens, muscles tense up and beads of sweat appear. This so-called “fight-or-flight” response served our ancestors well, but its continual activation in our modern-day lives comes with a cost. Each of our cells contains hundreds of small bean-shaped mitochondria — subcellular structures, or organelles, that provide the energy needed for normal functioning. But our fight-or-flight response places extreme demands on the mitochondria. The genetic cast-offs are not just inert cellular waste. To demonstrate psychological stress can cause mitochondrial DNA to be released by cells, Picard and his team devised a quick stress test. But how was this inflammation triggered by mitochondrial DNA leaking out of cells?
9 Key Components of the Shift to Higher Consciousness This article originally appeared in WakingTimes.com. Facing considerable political, economic, social and ecological crises, the human race is desperate for a transformation and a new direction. Business as usual ensures that we are doomed to run a course of half-conscious self-destruction, as man-made catastrophes multiply and stress mounts in every aspect of life. We must overthrow our ignorance, as it has become a fearful master, goading us into war, pollution, waste and exploitation. The social problems and entrenched patterns at the source of global issues are too vast and complex to be solved at the personal level, yet, paradoxically, the personal transformation of the individual offers a lonesome opportunity to avert the catastrophes we are engineering for ourselves. The shift. Personal evolution is both the great duty and the great joy of all human beings and is a process of divine significance, frequently unfolding in overlapping stages and related developments. 1. 2. 3. 4. 5.
DIY Skylights From Used Water Bottles Replace 50-Watt Bulbs Image via YouTube video An ingenious invention by an engineer in Brazil has made an enormous difference in his town. Simply placing a bottle of water in a hole in the ceiling can light up a room with the same brightness as a 50-watt light bulb! >> WATCH SLIDESHOW: 13 Really Cool Lighting Ideas (Slideshow) I think the part that made it most convincing was the bucket comparison -- when they took the buckets off the bottles to show what a difference they make in lighting the room, my jaw dropped open. While it's obvious that these only work for certain types of structures, and only provide extra light when the sun is out, it shows that you don't have to construct a complex skylight in your roof to get some daylight into your home. And to hear that the bottles are lasting years without needing any maintenance at all is exciting. What a great bottle-reuse-zero-electricity idea! UPDATE: The project is being called Liter of Light.
Why Time Slows Down When We’re Afraid, Speeds Up as We Age, and Gets Warped on Vacation by Maria Popova “Time perception matters because it is the experience of time that roots us in our mental reality.” Given my soft spot for famous diaries, it should come as no surprise that I keep one myself. Perhaps the greatest gift of the practice has been the daily habit of reading what I had written on that day a year earlier; not only is it a remarkable tool of introspection and self-awareness, but it also illustrates that our memory “is never a precise duplicate of the original [but] a continuing act of creation” and how flawed our perception of time is — almost everything that occurred a year ago appears as having taken place either significantly further in the past (“a different lifetime,” I’d often marvel at this time-illusion) or significantly more recently (“this feels like just last month!”). Discus chronologicus, a depiction of time by German engraver Christoph Weigel, published in the early 1720s; from Cartographies of Time. So what makes us date events more accurately?
Possibility of selectively erasing unwanted memories The human brain is exquisitely adept at linking seemingly random details into a cohesive memory that can trigger myriad associations -- some good, some not so good. For recovering addicts and individuals suffering from post-traumatic stress disorder (PTSD), unwanted memories can be devastating. Former meth addicts, for instance, report intense drug cravings triggered by associations with cigarettes, money, even gum (used to relieve dry mouth), pushing them back into the addiction they so desperately want to leave. Now, for the first time, scientists from the Florida campus of The Scripps Research Institute (TSRI) have been able to erase dangerous drug-associated memories in mice and rats without affecting other more benign memories. The surprising discovery, published this week online ahead of print by the journal Biological Psychiatry, points to a clear and workable method to disrupt unwanted memories while leaving the rest intact. Changing the Structure of Memory
Panic Attack Symptoms + 10 Unexpected Panic Attack Triggers Have you ever experienced panic attack symptoms? If you have, then you know that the sensations are so intense it feels like you could be having a heart attack or other serious health issue. Panic attacks are characterized by a fear of losing control or surviving a disaster, even though there is no real danger in that moment. There are many possible panic attack triggers, from bacterial infections to low blood sugar levels. If you aren’t familiar with the most common panic attack symptoms and some possible panic attack causes, a panic attack will certainly take you by surprise and feel like a life-threatening occurrence. Deconstructing a Panic Attack + Panic Attack Symptoms A panic attack is an intense and sudden development of fear or anxiety. Panic Attack vs Anxiety Attack: How Are They Different? Ever wonder, “What is an anxiety attack?” Signs of an anxiety attack vs. panic attack are important to differentiate. FatigueHypervigilanceRestlessnessIrritability What is a panic attack? Yes.
The Reptilian Aliens and the Council of the 13 'Royal' Families Excerpts from Blue Blood, True Blood: Conflict & Creation The leader of the Earth's Illuminati is called the "Pindar". ... Excerpts from Blue Blood, True Blood: Conflict & Creation The leader of the Earth's Illuminati is called the "Pindar". The Pindar is a member of one of the 13 ruling Illuminati families, and is always male. The title, Pindar, is an abbreviated term for "Pinnacle of the Draco". Symbolically, this represents the top of power, control, creation, penetration, expansion, invasion, and fear. The holder of this rank reports to the purebred Reptilian leader in the inner Earth. Recently, there are reports that the Marquis de Libeaux is the Pindar, but this is disinformation. He is based in Germany near Frankfurt. Interestingly, there is a winery on the east end of Long Island, not far from Montauk Point, called Pindar Vineyards. This fits nicely into the plan, as this area will be a part of the capital district of the Earth/United Nations in the Empire State! Publicly, Mr.
Interesting High-speed Video Clips Smithsonian X 3D Drugs That May Cause Memory Loss Side Effect How they can cause memory loss: Benzodiazepines dampen activity in key parts of the brain, including those involved in the transfer of events from short-term to long-term memory. Indeed, benzodiazepines are used in anesthesia for this very reason. When they're added to the anesthesiologist's cocktail of meds, patients rarely remember any unpleasantness from a procedure. Alternatives: Benzodiazepines should be prescribed only rarely in older adults, in my judgment, and then only for short periods of time. If you take one of these meds for insomnia, mild anxiety or agitation, talk with your doctor or other health care professional about treating your condition with other types of drugs or nondrug treatments. Be sure to consult your health care professional before stopping or reducing the dosage of any benzodiazepine.