http://www.youtube.com/watch?v=2pp17E4E-O8
Detecting Duchenne Muscular Dystrophy Name:___________________________________________Date:_____ The situation you will be dealing with is the following: Mary and John Smith have three children: Daniel, age 5; Alice, age 4; and Michael, age 1. Mary is two months pregnant. Recently Mary and John noticed that Daniel was having trouble climbing the stairs. Scientists Seek Ban on Method of Editing the Human Genome Photo A group of leading biologists on Thursday called for a worldwide moratorium on use of a new genome-editing technique that would alter human DNA in a way that can be inherited. The biologists fear that the new technique is so effective and easy to use that some physicians may push ahead before its safety can be assessed.
CRISPR-Cas9: des ciseaux génétiques pour le cerveau A l'occasion du prix Nobel de chimie attribué à Emmanuelle Charpentier et Jennifer Doudna, relisez notre article sur les ciseaux génétiques CRISPR-Cas9. En permettant d’intervenir sur l’ADN de manière chirurgicale, ceux-ci ne font pas que révolutionner les techniques d’édition du génome, ils ouvrent aussi des opportunités enthousiasmantes pour l’étude du cerveau. CRISPR-Cas9… Derrière cet acronyme barbare se cache une innovation révolutionnaire : remplacer un gène par un autre ou le modifier. La méthode paraît presque trop simple, et pourtant elle est le fruit de près de trente ans de recherche. CRISPR-Cas9 (prononcez « crispère ») fonctionne comme des ciseaux génétiques : il cible une zone spécifique de l’ADN, la coupe et y insère la séquence que l’on souhaite.
Using Karyotypes To Diagnose Genetic Disorders Sometimes chromosomes are incorrectly distributed into the egg or sperm cells during meiosis. When this happens, one cell may get two copies of a chromosome, while another cell gets none. Incorrect distribution of chromosomes is called nondisjunction. Human Embryo Editing Sparks Epic Ethical Debate In a world first, Chinese scientists have reported that they have used powerful gene-editing techniques to modify human embryos. Their paper, published in the Beijing-based journal Protein & Cell on April 18, came as no surprise to the scientific community, but it has ignited a wide-ranging debate about what types of gene-editing research are ethical. The publication also raises questions about the appropriate way to publish such work.
Does Sunscreen Protect my DNA? In this laboratory experiment students explore how effectively different sunscreens protect yeast cells from damage caused by ultraviolet (UV) radiation. DNA contains the instructions for proper cell function; changes to DNA can cause cancer; skin cancer can be caused by exposure to UV radiation, which comes from the sun; and the meaning of SPF ratings on sunscreens. Class Time: Two 45 minute class times Prep Time: 1-2 hours Does Sunscreen Protect my DNA?
New Discovery Moves Gene Editing Closer to Use in Humans A tweak to a technique that edits DNA with pinpoint precision has boosted its ability to correct defective genes in people. Called CRISPR, the method is already used in the lab to insert and remove genome defects in animal embryos. But the genetic instructions for the machinery on which CRISPR relies—a gene-editing enzyme called Cas9 and RNA molecules that guide it to its target—are simply too large to be efficiently ferried into most of the human body’s cells. This week, researchers report a possible way around that obstacle: a Cas9 enzyme that is encoded by a gene about three-quarters the size of the one currently used. The finding, published on 1 April in Nature, could open the door to new treatments for a host of genetic maladies (F. A.
Genetics Practice Problems Genetics Practice Problems You may type in your own answers, then check to see if you were right. If you’re totally stumped, you can tell the computer to show you the answer to a particular question. Monohybrid Cross: Apparently This Matters: New baby zonkey New baby zonkey Telegraph hangs out with his zebra mom at the Taigan zoo park in southern Crimea. Strange. No sign of his deadbeat donkey dad. What an ass. Telegraph's identity crisis will ultimately result in years of therapy. "Are you looking at my mom's butt? FDA urged to approve 'three-parent embryos' The United States should permit scientists to implant embryos with DNA from three genetic parents into women with certain diseases who otherwise wouldn’t be able to conceive a healthy child, an expert panel said Wednesday. The technique could open a new frontier in reproductive medicine and upend the fundamental truth of sexual reproduction, which merges DNA from one father and one mother to create a baby. The new procedure, which federal regulators are reviewing, would create an embryo with genetic material from two women and one man. It’s still in the experimental phase and will not be available in fertility clinics for some time.