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IMMUNE-MEDIATED THROMBOCYTOPENIA in dogs - Chinaroad Lowchens of Australia. A platelet is a cloud-shaped blood cell, neither related to the red blood cell line nor the white blood cell line.

IMMUNE-MEDIATED THROMBOCYTOPENIA in dogs - Chinaroad Lowchens of Australia

Platelets act in the clotting of blood in that they home to damaged areas of blood vessels, and “aggregate” there, meaning that they pile onto each other and bind, forming a small plug to seal the hole in the leaking blood vessel. Of course, large tears are too big for platelets to seal and there are other blood clotting mechanisms besides platelet aggregation but when it comes to small bleeds and normal blood vessel wear and tear, platelets are the star of the show. There is a saying that “platelets are vascular integrity and vascular integrity is platelets.” A small bleed unstaunched by a platelet aggregation quickly becomes a large bruise. Spontaneous bruising (in other words visible bruising from the normal wear and tear of one’s body) is a sign of reduced platelet numbers or poor platelet function. The usual patient is a middle-aged dog. Marvista Vet. Platelet Disorders: Hemostatic Disorders: Merck Veterinary Manual.

Disorders of platelets can be divided into acquired or congenital thrombocytopenias and acquired or congenital functional disorders (thrombocytopathias), with acquired thrombocytopenia being the most common.

Platelet Disorders: Hemostatic Disorders: Merck Veterinary Manual

Congenital Thrombocytopenia Hereditary Macrothrombocytopenia in Cavalier King Charles Spaniels This benign, inherited giant platelet disorder affects ~50% of dogs in the breed. It is characterized by thrombocytopenia with macrothrombocytes in 30% of cases and variable platelet aggregation in response to adenosine diphosphate, depending on the platelet count.

No correlation has been found between macrothrombocytopenia and age, gender, neuter status, coat color, weight, or heart murmur status. Cyclic Hematopoiesis in Gray Collie Dogs This autosomal recessive disorder is characterized by 12-day cycles of cytopenia. Platelet Disorders: Hemostatic Disorders: Merck Veterinary Manual. Disorders of platelets can be divided into acquired or congenital thrombocytopenias and acquired or congenital functional disorders (thrombocytopathias), with acquired thrombocytopenia being the most common.

Platelet Disorders: Hemostatic Disorders: Merck Veterinary Manual

Congenital Thrombocytopenia Hereditary Macrothrombocytopenia in Cavalier King Charles Spaniels This benign, inherited giant platelet disorder affects ~50% of dogs in the breed. It is characterized by thrombocytopenia with macrothrombocytes in 30% of cases and variable platelet aggregation in response to adenosine diphosphate, depending on the platelet count. No correlation has been found between macrothrombocytopenia and age, gender, neuter status, coat color, weight, or heart murmur status. Hematology: platelet count. Thrombocyte Dr Kathleen P Freeman Vetlexicon Canis ISSN: 1757-8256 This article is available in full to registered subscribers Sign up nowfor a 30 day trialor log in Overview Uses Alone.

Hematology: platelet count

Clotting Disorders of the Platelets in Dogs. Thrombocytopathies are defined as disorders of the blood platelet and abnormal functioning of the platelets.

Clotting Disorders of the Platelets in Dogs

Thrombocytopathic animals are those which typically have normal platelet counts on examination, but have spontaneous or excessive bleeding due to a failure of the platelets to bind to each other, or clot normally. Bleeding from the mucous membranes – nose, mouth ears, anus – is the most common sign. Thrombocytopathies may first become apparent in young animals when excessive bleeding occurs with the loss of baby teeth.

Thrombocytopathies can be acquired or hereditary; they affect the main functions of platelets: activation, adhesion and aggregation. That is, they lack the ability to group together and adhere to each other, an important function for sealing wounds. Symptoms and Types Causes. High Platelets in Blood Count, what does it mean? - Questions & Answers. Why Are My Dog Or Cat's Blood Platelet Counts Abnormal. Ron Hines DVM PhD Lots of my articles are plagiarized and altered on the web to market products and services.

Why Are My Dog Or Cat's Blood Platelet Counts Abnormal

There are never ads running or anything for sale with my real articles - other than my time. Try to stay with the ones with in the URL box or find all my articles at ACC.htm. Help! High platelets count - what steps to take? - Pet Forums Community. One of my cats, Lucky (2 years old, female, spayed, indoor, 3.25kg), was recently treated for a stomach bug which left her not eating or drinking, she was on a drip for a few days and finally started eating and drinking again, thank goodness!

Help! High platelets count - what steps to take? - Pet Forums Community

While she was sick she had a blood test done, which found a high platelet count (847 K/uL - normal range 175-600) with platelet aggregates detected and abnormal distribution. Vet at that point thought it could be at least partly down to dehydration. Anyway, now she's fully recovered from her stomach bug, I took her back to the vets for another blood test to see if everything had returned to normal. This time, the results said that her platelets count was "over 593", with again platelet aggregates detected and abnormal distribution. The vet said the aggregates were somehow interfering with the platelets count test and that's why there wasn't an exact figure, just "more than 593". The only other out-of-range result was a slightly low neutrophil count. Platelet count. Thrombocytopenia - Cat. Feline blood smear.

Thrombocytopenia - Cat

The small anucleated discoid-shaped cells with purple granules are normal cat platelets. Wright's stained; 100 x objective. Feline blood smear. There is a large macroplatelet present in the left center of the field. These can be seen in thrombocytopenic animals with active thrombopoiesis. Feline blood smear. Thrombocytopenia, a reduction in circulating thrombocytes (<300,000 platelets per microlitre), is a rare primary blood disorder of cats. Its opposite disorder, thrombocytosis also occurs in cats.