Febit. Fluidigm Corporation. FlexGen. LC Sciences. Recent major advances in DNA sequencing technologies have resulted in next-gen sequencing platforms capable of generating massive amounts of reads very quickly and relatively inexpensively. The new technologies are being effectively utilized for systematic study of genetic variation in certain targeted regions (subsets) of complex genomes[1]. By targeting specific regions, one can take better advantage of next-gen sequencing capability; essentially, more coverage is achieved by focusing reads on your area of interest.
LC Sciences’ µParaflo® technology is particularly well suited to provide sequence capture oligonucleotides through massively parallel synthesis of high quality DNA on biochips. Thousands of customer specified oligonucleotide sequences are in situ synthesized on a programmable high density microfluidics chip. LC Sciences has been synthesizing oligonucleotide libraries for use in capture applications since 2004[2].
Next-Gen Sequencing Applications Proven Technology. MYcroarray. MYbaits target enrichment kits are fully customizable sequence capture probe libraries that enable targeted sequencing (i.e., targeted Next Generation Sequencing, or targeted NGS). MYbaits target enrichment is based on the efficient in-solution hybridization capture of target DNA using biotinylated RNA baits that are complementary to target sequences. Target enrichment with sequence capture kits, such as the MYbaits target capture kit, is commonly used to perform gene enrichment, loci enrichment, or exon enrichment (gene capture, loci capture, or exon capture) for applications such as whole exome sequencing.
For such applications, we offer cancer exome capture kits and whole exome capture kits. We offer personalized customer service and competitive pricing for custom sequence capture probe libraries (bait libraries). Our design team has more than a decade of experience designing molecular probes and will work with you directly to design the sequence capture kit that meets your needs. Olink Genomics. Population Genetics Technologies. Qiagen.
RainDance Technologies. Roche NimbleGen. SeqCap EZ Library is a solution-based capture method that enables enrichment of the whole exome or customer regions of interest in a single test tube. Built upon an optimized design algorithm, SeqCap EZ Library sets a new standard for a simple single-step enrichment method. SeqCap EZ Exome Libraries enable enrichment of the whole exome. Based on the latest database builds and offering a 64Mb sequence capture, SeqCap EZ Exome Library v3.0 enables the discovery of more coding variants. SeqCap EZ Exome Library v2.0 sets a new standard for exome sequencing by giving you the power to capture and sequence the exome on a single lane. SeqCap EZ Exome +UTR Library offers a 96 Mb design to capture the exome and untranslated regions (UTRs). SeqCap EZ Developer Libraries enable enrichment of customer regions of interest in non-human genomes.
SeqCap EZ Designs offer maximum performance for focused research areas, developed in collaboration with researchers like you. SeqCap EZ Designs.