Journal of Mathematical Psychology | Vol 56, Iss 5, Pgs 287-394, (October, 2012) Opiate Receptor: Demonstration in Nervous Tissue. Cerebral protein synthesis in a genetic mouse model of phenylketonuria. Author Affiliations Communicated by Louis Sokoloff, National Institutes of Health, Bethesda, MD (received for review April 6, 2000) Abstract Local rates of cerebral protein synthesis (lCPSleu) were measured with the quantitative autoradiographic [1-14C]leucine method in a genetic mouse model (Pahenu2) of phenylketonuria. As in the human disease, Pahenu2 mice have a mutation in the gene for phenylalanine hydroxylase. We compared adult homozygous (HMZ) and heterozygous (HTZ) Pahenu2 mice with the background strain (BTBR). Arterial plasma concentrations of phenylalanine (Phe) were elevated in both HMZ and HTZ mutants by 21 times and 38%, respectively. In the total acid-soluble pool in brain concentrations of Phe were higher and other neutral amino acids lower in HMZ mice compared with either HTZ or BTBR mice indicating a partial saturation of the l-amino acid carrier at the blood brain barrier by the elevated plasma Phe concentrations.
Materials and Methods Chemicals. Animals. Genotyping. Human Behavior, Learning, and the Developing Brain: Typical Development - Donna Coch, Kurt W. Fischer, Geraldine Dawson. Pathguide: the pathway resource list. APA Reference Style - 6th edition 2010. General Development of the Nervous System - Basic Neurochemistry - NCBI Bookshelf. Basic Neurochemistry: Principles of Molecular, Cellular, and Medical ... - George J. Siegel, Scott Brady. Fulltext.pdf (application/pdf Object) 1-s2.0-S0959438809000567-main.pdf (application/pdf Object) Serials Solutions 360 Link. Web of Knowledge [v.5.5] - Web of Science. Web of Knowledge [v.5.5] - Web of Science Full Record.
History of Neuroscience. The History of Neuroscience reveals the field's evolution to present day. The work of neuroscience pioneers has produced vital knowledge about the brain and nervous system that is advancing today’s science and improving health outcomes. As with any scientific endeavor, more knowledge has produced new mysteries. For that reason, The History of Neuroscience not only informs understanding of the past and honors progress, but also becomes part of a living story of scientific inquiry and sets a course for future discovery and progress.
SfN maintains this historical material as a resource for neuroscientists and the public. While not comprehensive, the documents chronicle the struggles and accomplishments of a still-young field and highlight major achievements and advances. Most of all, this information conveys the rigor and passion with which neuroscientists pursue scientific discovery. Learn about the history of SfN. Gale Power Search - Document. Cognition, Brain, and Consciousness: Introduction to Cognitive Neuroscience - Bernard J. Baars, Nicole M. Gage. Depression: Concepts, Controversies, and Some New Facts - Eugene E. Levitt, Keith E. Nelson, Bernard Lubin, James M. Brooks. 53-1955.pdf (application/pdf Object) Without Miracles: Brain Evolution and Development: The Selection of Neurons and Synapses. Without Miracles 5 Brain Evolution and Development: The Selection of Neurons and Synapses Instruction versus Selection The 10,000 or so synapses per cortical neuron are not established immediately.
--Jean-Pierre Changeux[1] The most complex object yet discovered anywhere in the universe is the organ that fills the space between our ears. Although there are many different types of neurons, almost all of them share certain common features as portrayed in figure 5.1. The ways in which neurons are specialized to carry out their communicative function is made evident by closer examination of the appendages they sport, that is, their dendrites and axons. For one neuron to influence another, the two must be connected, and this is accomplished by junctions called synapses (figure 5.2). How this unfathomably complex organization allows us to perceive, behave, think, feel, and control our environment presents us with what may be the most striking puzzle of fit we have yet encountered. ZERO TO THREE: ScienceDirect.com - Biochemical Education - Neurochemistry: Edited by I P Ashmarin and P V Stoukalov. pp 469. [In Russian]. Institute of Biomedical Chemistry, Moscow. 1996.
Gale Power Search - Document. Serials Solutions 360 Link. Gale Power Search - Document. Gale Power Search - Document. Epigenetic regulation of self-renewal and fate determination in neural stem cells - Mohamed Ariff - 2011 - Journal of Neuroscience Research - Wiley Online Library. The limits of brain determinacy. Academic OneFile - PDF View.