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Dolan DNA Learning Center

Dolan DNA Learning Center
Animations can be viewed within your web browser or downloaded for play from your computer. In some genes the protein-coding sections of the DNA ("exons") are interrupted by non-coding regions ("introns"). RNA splicing removes the introns from pre mRNA to produce the final set of instructions for the protein. Transcript: As DNA is transcribed into RNA it needs to be edited to remove non-coding regions, or introns, shown in green. RNA splicing begins with assembly of helper proteins at the intron/exon borders. This process is repeated for every intron in the RNA.

No known hominin is common ancestor of Neanderthals and modern humans, study suggests -- ScienceDaily The search for a common ancestor linking modern humans with the Neanderthals who lived in Europe thousands of years ago has been a compelling subject for research. But a new study suggests the quest isn't nearly complete. The researchers, using quantitative methods focused on the shape of dental fossils, find that none of the usual suspects fits the expected profile of an ancestor of Neanderthals and modern humans. The study, which will be published online this week by the Proceedings of the National Academy of Sciences, was carried out by an international team of scholars from The George Washington University, Konrad Lorenz Institute for Evolution and Cognition Research in Austria, Indiana University and Atapuerca Research Team in Spain. P. The researchers use techniques of morphometric analysis and phylogenetic statistics to reconstruct the dental morphology of the last common ancestor of Neanderthals and modern humans. What comes next?

Making a Genealogy Map Using the Google Maps API Introduction I wanted to try out using the Google Maps API for a project, so I decided I’d try to use it in conjunction with some genealogy data to see what I could come up with. The result is a family tree which is mapped out spatially rather than chronologically; once rendered, the following visual data is revealed: Migration paths - see where particular people suddenly moved a large distance Geographical density/immobility - see which areas the most family members were from Most popular places - see which villages or cities successive generations lived in Example Click on the image below to view a live example of the project (using real data from my family tree) and then read on for an explanation of how the program works: Features Google Maps features: Pan and zoom around the map using AJAX technology Switch to vector mapping, satellite mapping or hybrid maps Program features: By way of compromise, it is possible to adjust the zoom level via a variable at the top of the program though. Code

Mendelian Genetics An important question to answer in any genetic experiment is how can we decide if our data fits any of the Mendelian ratios we have discussed. A statistical test that can test out ratios is the Chi-Square or Goodness of Fit test. Chi-Square Formula Degrees of freedom (df) = n-1 where n is the number of classes Let's test the following data to determine if it fits a 9:3:3:1 ratio. Number of classes (n) = 4 df = n-1 + 4-1 = 3 Chi-square value = 0.47 Enter the Chi-Square table at df = 3 and we see the probability of our chi-square value is greater than 0.90. A Chi-Square Table Copyright © 2000.

European Neanderthals were on the verge of extinction even before the arrival of modern humans New findings from an international team of researchers show that most Neanderthals in Europe died off around 50,000 years ago. The previously held view of a Europe populated by a stable Neanderthal population for hundreds of thousands of years up until modern humans arrived must therefore be revised. This new perspective on the Neanderthals comes from a study of ancient DNA published February 25 in Molecular Biology and Evolution. The results indicate that most Neanderthals in Europe died off as early as 50,000 years ago. After that, a small group of Neanderthals recolonised central and western Europe, where they survived for another 10,000 years before modern humans entered the picture. The study is the result of an international project led by Swedish and Spanish researchers in Uppsala, Stockholm and Madrid. The results presented in the study are based entirely on severely degraded DNA, and the analyses have therefore required both advanced laboratory and computational methods.

The Animal Files The PCR Method - a DNA Copying Machine Lists of Nobel Prizes and Laureates The PCR Method - a DNA Copying Machine Play the Eye of the Donkey Game About the game PCR is a method by which a few fragments of DNA can be duplicated into millions in a couple of hours. This makes PCR a very useful method in, amongst other fields, forensic science. The Nobel Prize The 1993 Nobel Prize in Chemistry was awarded for the invention of PCR, a method that made it possible to copy a large numbers of DNA fragments in only a few hours. Share this: Share on facebook Share on google_plusone_share Share on twitter More Sharing Services Share on email To cite this pageMLA style: "The PCR Method - a DNA Copying Machine". Recommended: The Legacy of Alfred Nobel On 27 November 1895 Alfred Nobel signed his last will in Paris. Play the Blood Typing Game Try to save some patients and learn about human blood types! Unlocking the Secrets of Our Cells Discover the 2012 awarded research on stem cells and cell signalling. Contact E-mail us Press Sitemap A-Z Index Terms

Neanderthals died out earlier than previously thought, new evidence suggests Direct dating of a fossil of a Neanderthal infant suggests that Neanderthals probably died out earlier than previously thought. Researchers have dated a Neanderthal fossil discovered in a significant cave site in Russia in the northern Caucasus, and found it to be 10,000 years older than previous research had suggested. This new evidence throws into doubt the theory that Neanderthals and modern humans interacted for thousands of years. Instead, the researchers believe any co-existence between Neanderthals and modern humans is likely to have been much more restricted, perhaps a few hundred years. The research, directed by the University of Oxford and University College Cork in collaboration with the Laboratory of Prehistory at St Petersburg, Russia, and funded by Science Foundation Ireland was recently published in PNAS Online Early Edition. The new dating evidence throws new light on when the Neanderthals became extinct and why.

Genetics Course|Biology Course Summary This course is based on 7.03 Genetics, Fall 2004 made available by Massachusetts Institute of Technology: MIT OpenCourseWare under the Creative Commons BY-NC-SA license. This course discusses the principles of genetics with application to the study of biological function at the level of molecules, cells, and multicellular organisms, including humans. Reading Material 1. Course Material Not available. Other Resources 1. Software

Bunnies implicated in the demise of Neanderthals - 27 February 2013 BLAME it on the bunnies. The debate over what Neanderthals ate, and how it may have led to their demise, has turned to rabbits. Which, it is now claimed, they did not feast on. Signs that our extinct cousins hunted dolphins and seals were presented in 2008 as evidence of their sophistication. Now, John Fa of the Durrell Wildlife Conservation Trust in Trinity, Jersey, says the remains in caves around Europe became dominated by rabbits rather than large game around the time Neanderthals went extinct (Journal of Human Evolution, doi.org/kkn). It's not clear why they would have had more trouble changing prey, says Fa.

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