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The Science Behind Foldit

The Science Behind Foldit
Foldit is a revolutionary new computer game enabling you to contribute to important scientific research. This page describes the science behind Foldit and how your playing can help. What is a protein? What are amino acids? What shape will a protein fold into? Why is shape important? What do proteins do? Amylase starts the process of breaking down starch from food into forms the body can use.Alcohol dehydrogenase transforms alcohol from beer/wine/liquor into a non-toxic form that the body uses for food.Hemoglobin carries oxygen in our blood.Fibrin forms a scab to protect cuts as they heal.Collagen gives structure and support to our skin, tendons, and even bones.Actin is one of the major proteins in our muscles.Growth hormone helps regulate the growth of children into adults.Potassium channels help send signals through the brain and other nerve cells.Insulin regulates the amount of sugar in the blood and is used to treat diabetes. What big problems is this game tackling? Related:  Learning GamesGames Theorize

Galaxy Zoo Gamers succeed where scientists fail Public release date: 18-Sep-2011 [ Print | E-mail Share ] [ Close Window ] Contact: Leila Grayleilag@u.washington.edu 206-685-0381University of Washington Gamers have solved the structure of a retrovirus enzyme whose configuration had stumped scientists for more than a decade. The gamers achieved their discovery by playing Foldit, an online game that allows players to collaborate and compete in predicting the structure of protein molecules. After scientists repeatedly failed to piece together the structure of a protein-cutting enzyme from an AIDS-like virus, they called in the Foldit players. This class of enzymes, called retroviral proteases, has a critical role in how the AIDS virus matures and proliferates. "We wanted to see if human intuition could succeed where automated methods had failed," said Dr. Remarkably, the gamers generated models good enough for the researchers to refine and, within a few days, determine the enzyme's structure. Players come from all walks of life. Dr.

Homeschooled children have higher graduation rates, more social prowess (NaturalNews) Homeschooling, once steeped in negativity and subject to eyebrow-raising naysayers, is fast-sweeping the nation as an alternative educational method that comes with higher graduation rates than traditional schooling.(1) In fact, there are approximately 2.2 million students in the United States who receive home education, and experts note that its popularity has continued, rather than waned, through the years. These students have been found to score up to 30 percentile points above public-school students on standardized academic achievement tests.(2) With homeschooling, children are taught under the direction of family members who maintain that learning at home allows youngsters to obtain customized instruction that public schools do not regularly provide, while simultaneously strengthening family relationships in a safe environment.(2) Higher graduation rates, test scores among homeschooled children Homeschooled children more prepared socially for real-world scenarios

Gamers beat algorithms at finding protein structures Today's issue of Nature contains a paper with a rather unusual author list. Read past the standard collection of academics, and the final author credited is... an online gaming community. Scientists have turned to games for a variety of reasons, having studied virtual epidemics and tracked online communities and behavior, or simply used games to drum up excitement for the science. But this may be the first time that the gamers played an active role in producing the results, having solved problems in protein structure through the Foldit game. According to a news feature on Foldit, the project arose from an earlier distributed computing effort called Rosetta@home. That project used what has become the standard approach for home-based scientific work: a screensaver that provided a graphical frontend to a program that uses spare processor time to solve weighty scientific problems. This is typically an energy minimization problem. Starting with algorithms, ending with brains

Socialization: Tackling Homeschooling's "S" Word . Education . PBS Parents The mainstream perception of homeschool students is that they are an antisocial bunch, toiling away lonely hours at a kitchen table with only their parents for friends. But homeschoolers themselves will tell you that socialization—the “S-word,” as some call it—is really a nonissue. “Socialization is always the hot topic,” says Kate Fridkis, an adult who was unschooled until she was college age. Fridkis, who blogs about homeschooling at skipping-school.com, says that when she tells people she was homeschooled, they often respond by asking if she had any friends. “People seem to translate the term [homeschooling] literally into ‘school in the home,'” she says. “But you’re actually socializing so much more than your average kid who’s sitting in class all day.” For Fridkis, homeschooling gave her the freedom to immerse herself in her community—and to develop relationships with people who were outside of her age group. National Home Education Research Institute president Brian Ray agrees.

Right on queue As the queues formed down the street outside branches of Northern Rock this week, it was obvious enough to a game theorist what was going on: people had decided to hunt rabbits. Bear with me – this will make sense in a moment. Game theory is the study (by economists, mathematicians, biologists and others) of situations where what you do may affect what I choose to do, and what I do may affect what you choose to do. The theory is big on catchy stories with memorable names, but ultimately it is all about mathematical representations of interactive decisions, called “games”. The most famous game of all is the “prisoners’ dilemma”, in which two prisoners must each decide whether to plea-bargain by giving evidence against the other. But another game, the “stag hunt”, languishes in relative and undeserved obscurity. There are two rational outcomes to the stag hunt: either both hunters hunt the stag as a team, or each hunts rabbits by himself.

Research Facts on Homeschooling | Research Brian D. Ray, Ph.D.January 6, 2015 Download/Print PDF Version General Facts and Trends · Homeschooling – that is, parent-led home-based education – is an age-old traditional educational practice that a decade ago appeared to be cutting-edge and “alternative” but is now bordering on “mainstream” in the United States. · There are about 2.2 million home-educated students in the United States. · Families engaged in home-based education are not dependent on public, tax-funded resources for their children’s education. · Homeschooling is quickly growing in popularity among minorities. · A demographically wide variety of people homeschool – these are atheists, Christians, and Mormons; conservatives, libertarians, and liberals; low-, middle-, and high-income families; black, Hispanic, and white; parents with Ph.D.s, GEDs, and no high-school diplomas. Reasons for Home Educating Most parents and youth decide to homeschool for more than one reason. · accomplish more academically than in schools, Sources

Seas Labs SEAS is the Synthetic Environment for Analysis and Simulations engine that enables researchers and organizations to try out their models or techniques in a publicly known, realistically detailed environment, but without the logistical problems associated with actually installing the system in a real firm. SEAS provides valuable interaction among researchers, between researchers and industrial users, and allows students to practice what is learned through a safe, controlled synthetic environment. This synthetic environment addresses the rapidly changing technology and academic culture - which makes it difficult for researchers to gain direct experience with the realities of an enterprise - and the isolation from the details of the real world of research in business decision-making - making it difficult for researchers to compare the effectiveness of different approaches.

Origami Instructions - Instructions on How to Make Origami Parrondo's paradox Parrondo's paradox, a paradox in game theory, has been described as: A combination of losing strategies becomes a winning strategy. It is named after its creator, Juan Parrondo, who discovered the paradox in 1996. A more explanatory description is: There exist pairs of games, each with a higher probability of losing than winning, for which it is possible to construct a winning strategy by playing the games alternately. Parrondo devised the paradox in connection with his analysis of the Brownian ratchet, a thought experiment about a machine that can purportedly extract energy from random heat motions popularized by physicist Richard Feynman. However, the paradox disappears when rigorously analyzed.[1] Illustrative examples[edit] The saw-tooth example[edit] Figure 1 Consider an example in which there are two points A and B having the same altitude, as shown in Figure 1. Figure 2 It easily follows that eventually we will have marbles at point A, but none at point B. and The role of Name[edit]

amazon The Emerging Revolution in Game Theory The world of game theory is currently on fire. In May, Freeman Dyson at Princeton University and William Press at the University of Texas announced that they had discovered a previously unknown strategy for the game of prisoner’s dilemma which guarantees one player a better outcome than the other. That’s a monumental surprise. The game is this: imagine Alice and Bob have committed a crime and are arrested. What should Alice and Bob do? If they co-operate, they both spend only one month in jail. However, the game gets more interesting when played in repeated rounds because players who have been betrayed in one round have the chance to get their own back in the next iteration. Until now, everyone thought the best strategy in iterative prisoner’s dilemma was to copy your opponents behaviour in the previous round. That conclusion was based on decades of computer simulations and a certain blind faith in the symmetry of the solution. Game theorists call this the Ultimatum Game.

ORILAND - What Origami Can Be! Game Theory – Prisoners Dilemma to Inspection Game to Metagame | econfix Home > Behavioural Economics, Sport > Game Theory – Prisoners Dilemma to Inspection Game to Metagame Drug-taking in professional sport has long been a major concern and there is no better example than seven times Tour de France winner Lance Armstrong who admitted to doping. Furthermore in the period from 1997 until 2002 among 64 world class 100 metre sprinters 25% have been convicted of doping and this doesn’t include two American sprinters who tested positive this year. Prisoners Dilemma to Inspection Game to Metagame Game theory deals with differences of opinion between groups who know each other’s inclination but not their genuine objective or choice. Athletes – Dope or Clean (D C) Organisers – Test or No Test (T N) Customer – Stay or Leave (S L) In the figure below organisers decide on the testing the athletes whether there was doping or not. The assumptions are as follows: Athletes D-N-S > C-N-S = athletes prefer to dope if not tested. econoMAX Like this: Like Loading...

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