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Structurally and functionally accurate bioprinted human tissue models

Structurally and functionally accurate bioprinted human tissue models

http://www.organovo.com/homepage

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3D-Printed Rocket Parts Excel in NASA Tests Key rocket parts built using 3D-printing technology have passed another round of NASA firing tests, inspiring further confidence among space agency officials in this emerging manufacturing technique. Two rocket engine injectors made with a 3D printer performed as well as traditionally constructed parts during recent hot-fire tests, which exposed them to temperatures approaching 6,000 degrees Fahrenheit (3,316 degrees Celsius) and extreme pressures, NASA officials announced Wednesday (July 24). The recent tests, performed at NASA's Marshall Space Flight Center in Huntsville, Ala., followed closely on the heels of other successful hot-fire trials of 3D-printed engine injectors conducted at the agency's Glenn Research Center in Ohio. [See video of the Marshall hot-fire tests]

TED 2013: 4D printed objects 'make themselves' 28 February 2013Last updated at 05:39 ET By Jane Wakefield Technology reporter Video of cube self-folding strand courtesy Self-Assembly Lab, MIT/Stratasys Many are only just getting their heads around the idea of 3D printing but scientists at MIT are already working on an upgrade: 4D printing. Tech Biz Chinese Scientists Are 3D Printing Ears and Livers – With Living Tissue Specially modified 3D printers use live cells that could theoretically be transplanted. Researchers in China have been able to successfully print human organs using specialized 3D printers that use living cells instead of plastic. Researchers at Hangzhou Dianzi University actually went as far as inventing their own 3D printer for the complex task, dubbed the “Regenovo.” “Xu Mingen, Regenovo's developer, said that it takes the printer under an hour to produce either a mini liver sample or a four to five inch ear cartilage sample. Xu also predicted that fully functional printed organs may be possible within the next ten to twenty years,” stated 3D Printer World. According to Xu, the Regenovo can print in a sterilized environment with temperatures ranging between 23 and 500 degrees Fahrenheit.

Welcome to the Forgacslab Website Engineering biological structures of prescribed shape using self-assembling multicellular systems, Proc. Natl. Acad. Sci. USA 101,2864-2869(2004) Bioprinting - WFIRM - Wake Forest Baptist Medical Center Living tissues are composed of many cell types that are all arranged in a very specific order in three-dimensional space. Maintaining this order is essential to ensure engineered tissues and organs maintain the same functionality that original body parts have. Researchers at the Wake Forest Institute for Regenerative Medicine are using modified ink-jet technology to build a variety of tissue and organ prototypes. This technology allows multiple cell types and other tissue components to be arranged in pre-determined locations with high precision. In an early form of the technology, various cell types were placed in the wells of an actual ink cartridge and a printer was programmed to arrange the cells in a pre-determined order. Watch this early "bioprinting" technology in action below:

Bill to Ban Undetectable 3D Printed Guns Is Coming Back Since Congressman Steve Israel first called for legislation that would ban 3-D printed guns, those plastic-printed firearms have evolved from a few simple components to a full one-shot pistol to rifles and multi-shot revolvers, with more advances on the horizon. Israel’s bill, meanwhile, has gone nowhere, leaving a widening gap between DIY weapons and the law. But the representative from New York says he hasn’t given up: In the next few months, Israel’s office tells WIRED he plans to reintroduce legislation that would ban 3-D printed guns or any other fully-plastic firearm. University Biofabrication Lab Biofabrication uses cells or biologics as basic building blocks in which biological models, systems, devices and products are manufactured. Biofabrication techniques encompass a broad range of physical, chemical, biological, and/or engineering process, with various applications in tissue science and engineering, regenerative medicine, disease pathogeneses and drug testing studies, biochips and biosensors, cell printing, patterning and assembly, and organ printing. The Program for Biofabrication at Drexel integrates computer-aided tissue engineering, modern design and manufacturing, biomaterials and biology in modeling, design, and biofabrication of tissue scaffolds, tissue constructs, micro-organ, tissue models. The on-going research focuses on: bio-tissue modeling, bio-blueprint modeling, scaffold informatics modeling, biomimetic design of tissue scaffold, additive manufacturing of tissue scaffolds, cell printing and organ printing. 6) MTS universal testing system

Breakthrough: 3D printer creates artificial human tissue April 4, 2013 Oxford University scientists have developed a custom-built programmable 3D printer that can create materials with several of the properties of living tissues. The new type of material consists of thousands of connected water droplets that are encapsulated within lipid films, which can perform some of the functions of the cells inside our bodies. Scientists say these printed 'droplet networks' could be the building blocks of a new kind of technology for delivering drugs to places where they are needed, or potentially one day replacing or interfacing with damaged human tissues. "We aren't trying to make materials that faithfully resemble tissues but rather structures that can carry out the functions of tissues," said Professor Hagan Bayley of Oxford University's Department of Chemistry, who led the research. "We've shown that it is possible to create networks of tens of thousands connected droplets.

Hardware Designs Should Be Free. Here's How to Do It We must design free hardware. But the question remains: how? First, we must understand why we can’t make hardware free the same way we make software free. Hardware and software are fundamentally different. A program, even in compiled executable form, is a collection of data which can be interpreted as instruction for a computer. Wohlers Associates - Terry Wohlers Terry WohlersShort Biography Industry consultant, analyst, author, and speaker Terry Wohlers is president of Wohlers Associates, Inc., an independent consulting firm he founded 27 years ago. The company provides technical and strategic consulting on the new developments and trends in rapid product development, additive manufacturing, and 3D printing. Through this company, Wohlers has provided consulting assistance to more than 240 organizations in 24 countries. Also, he has provided advice to 150+ companies in the investment community, most being institutional investors that represent mutual funds, hedge funds, and private equity valued at billions of dollars.

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