background preloader

Retraction Watch - Tracking retractions as a window into the scientific process at Retraction Watch

Retraction Watch - Tracking retractions as a window into the scientific process at Retraction Watch
Wrong cell line leads to retraction of kidney cancer study A group of authors in China has retracted their December 2013 paper in PLoS ONE after realizing that they’d been studying the wrong cells. The paper, “Up-Regulation of pVHL along with Down-Regulation of HIF-1α by NDRG2 Expression Attenuates Proliferation and Invasion in Renal Cancer Cells,” came from Lei Gao, of the Fourth Military Medical University, in Xi’an, and colleagues. It purported to find that: Read the rest of this entry » Retractions appear in case of former Kansas water scientist rebuked for misconduct

http://retractionwatch.com/

Related:  Publications scientifiquesCitizen ScientistReproducibilidad de la cienciaMedical Research & EBMBad docs bad drugs

Falsification, Fabrication, and Plagiarism: The Unholy Trinity of Scientific Writing Article Outline One of the greatest, and sadly all too common, challenges facing a contemporary medical journal editor is the adjudication of ethical integrity issues. I had originally presumed that this would be just an occasional role, but it transpires that these problems are quite widespread, ranging from unconscious and unwitting naiveté to the conscious and willful betrayal of scientific trust. As a journal, we have no significant powers of investigation, and determining, often years after publication, what is truth and what is fiction can be impossibly hard. The International Journal of Radiation Oncology · Biology · Physics (the Red Journal) editorial board wishes to lay down an unambiguous, bright line that distinguishes the acceptable from the unacceptable so that no author can, in retrospect, say they were not warned. In medical research, we hold great responsibility and trust, and thus aspire to a conduct of unassailable honesty and integrity in its execution.

5 Popular Medications You Won't Believe Mess With Your Brain If you want to terrify yourself, go into your medicine cabinet and read all of the really weird side effects at the bottom of the label. Beyond the normal "headache" or "upset stomach," you get weird shit that reads like ironic punishments from a vengeful genie. Sure, most users won't see this kind of black magic side effects, but that just means you're all the more surprised when you run into ... #5. The Flu Medication That Can Cause Psychosis Hemera Technologies/AbleStock.com Origin of polar auroras revealed Researchers from UCL, University of Southampton and Cambridge University together with ESA and NASA have uncovered the origin of a colourful display in the night sky called ‘theta aurora’, explaining for the first time how auroras at high-latitudes form. Auroras are the most visible manifestation of the sun’s effect on Earth, but many aspects of these spectacular displays are still poorly understood. The team’s findings published in Science today show the role hot plasma, which comprises electrically charged atomic particles, plays in producing the unusual theta aurora. Theta aurora is so named because when seen from above it looks like the Greek letter theta – an oval with a line crossing through the centre.

Map: explore the human disease network. Dataset, interactive map and printable poster of gene-disease relationships. Curious about the Diseasome map? Here are some answers to the most common questions asked: I. Drawing the map The Diseasome map is composed of 516 diseases and 903 genes - using the data of Marc Vidal, Albert-Laszlo Barabasi and Michael Cusick. The diseases are divided into twenty-two different categories: 5 Common Medical Procedures (That Secretly Aren't Worth It) A thousand years ago, consulting a doctor about abdominal pains would have earned you a week in bed, covered with leeches, while a shaman sprayed chicken blood all over your torso. These days it seems to most of us that medical science has advanced a little since then. Well, we hate to break it to you, but many of the common procedures in use today are about as useful, if not more dangerous, than that bucket of leeches from ages past. CT scans are what doctors describe to stupid people as "super X-rays."

Group blogs: BMJ The BMJ Today: If you hear hoof beats in Texas think of horses, not zebras As Saurabh Jha writes, “The likelihood that someone with cerebral aneurysm hit by a bat develops subarachnoid hemorrhage (near certainty) is not the same as the likelihood that someone who develops subarachnoid hemorrhage after high impact trauma has an aneurysm, hitherto undisclosed (very low).” But would you order tests so you could absolutely rule it out? Would you perhaps order further tests to rule out bleeding brain metastases from lung cancer? Jha asks us to stop “hunting for zebras in Texas” and put an end the “rule-out” culture that pervades medicine. more… Desmond O’Neill: Combatting rigidity in medicine

This surreal timelapse shows what earth looks like from the International Space Station During his six-month stay on the International Space Station, German astronaut Alexander Gerst took more than 12,500 photos — of the Milky Way, the aurora borealis, the illumination produced by cities at night, and all other sorts of beautiful sights that we can't see well living down here on earth. Today, as spotted by the Washington Post's Rachel Feltman, the European Space Agency released a video that knits together some of these photos into a series of astounding time lapses. The video is so surreal that at times, it looks like you're watching a computer rendering, rather than actual footage.

Why Most Published Research Findings Are False Summary There is increasing concern that most current published research findings are false. The probability that a research claim is true may depend on study power and bias, the number of other studies on the same question, and, importantly, the ratio of true to no relationships among the relationships probed in each scientific field. In this framework, a research finding is less likely to be true when the studies conducted in a field are smaller; when effect sizes are smaller; when there is a greater number and lesser preselection of tested relationships; where there is greater flexibility in designs, definitions, outcomes, and analytical modes; when there is greater financial and other interest and prejudice; and when more teams are involved in a scientific field in chase of statistical significance.

5 Terrifying Things Nobody Tells You About Health Care If you're reading this, congratulations! You're probably not currently unconscious in an intensive care unit, surrounded by a gaggle of improbably sexy doctors who use your humorously gained pelvic injuries as a metaphor for their relationship issues. However, as a Cracked reader, there's a pretty good chance that someday you will be (we know our audience). Still, there is no need to go unprepared! Here is a handy manual for the unexpected shocks and nasty surprises you are likely to encounter during your time on the health care carousel. #5.

Data Diving TIP OF THE ICEBERG: Independent reviewers of clinical trial data have access to just a minuscule percentage of the actual information.Pushart TIP OF THE ICEBERG: Independent reviewers of clinical trial data have access to just a minuscule percentage of the actual information. PUSHART A few weeks before Christmas 2009, the world was in the grip of a flu pandemic. Sun Sizzles in High-Energy X-Rays [image-50] For the first time, a mission designed to set its eyes on black holes and other objects far from our solar system has turned its gaze back closer to home, capturing images of our sun. NASA's Nuclear Spectroscopic Telescope Array, or NuSTAR, has taken its first picture of the sun, producing the most sensitive solar portrait ever taken in high-energy X-rays. The image is available at: "NuSTAR will give us a unique look at the sun, from the deepest to the highest parts of its atmosphere," said David Smith, a solar physicist and member of the NuSTAR team at University of California, Santa Cruz. Solar scientists first thought of using NuSTAR to study the sun about seven years ago, after the space telescope's design and construction was already underway (the telescope launched into space in 2012).

6 Bullshit Facts About Psychology That Everyone Believes Psychology is one of those subjects that everybody likes to think they know something about. We love to go around diagnosing our friends and co-workers, both to make sense of the world and to make ourselves feel like we're smarter than they are. But like any science that makes its way into the pop culture, a lot of the "common sense" statements we hear every day are so wrong that they border on raving idiocy. Such as... "If You Let Your Anger Out, You'll Feel Better!" You always hear people talk about how "cathartic" an experience was and how much better they feel, or you'll hear them say things like, "If you keep your anger bottled up, one day you'll just snap!"

Designing conference posters » Colin Purrington A large-format poster is a big piece of paper or wall-mounted monitor featuring a short title, an introduction to your burning question, an overview of your novel experimental approach, your amazing results in graphical form, some insightful discussion of aforementioned results, a listing of previously published articles that are important to your research, and some brief acknowledgement of the tremendous assistance and financial support conned from others — if all text is kept to a minimum (less than a 1000 words), a person could fully read your poster in 5-10 minutes. Section content • DOs and DON’Ts • Adding pieces of flair • Presenting • Motivational advice • Software • Templates • Printing • Useful literature • Organizing a poster session What to put in each section Below, I’ve provided rough tips on how many words each of these sections might have, but those guesses are assuming you have a horizontal poster that is approximately 3×4′.

Why we need to listen to the real experts in science If we want to use scientific thinking to solve problems, we need people to appreciate evidence and heed expert advice. But the Australian suspicion of authority extends to experts, and this public cynicism can be manipulated to shift the tone and direction of debates. We have seen this happen in arguments about climate change.

Related: